دورية أكاديمية
Therapeutic approaches for portal biliopathy: A systematic review
| العنوان: | Therapeutic approaches for portal biliopathy: A systematic review |
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| المؤلفون: | FRANCESCHET, IRENE, ZANETTO, ALBERTO, FERRARESE, ALBERTO, BURRA, PATRIZIA, SENZOLO, MARCO |
| المساهمون: | Franceschet, Irene, Zanetto, Alberto, Ferrarese, Alberto, Burra, Patrizia, Senzolo, Marco |
| بيانات النشر: | Baishideng Publishing Group Co., Limited |
| سنة النشر: | 2016 |
| المجموعة: | Padua Research Archive (IRIS - Università degli Studi di Padova) |
| مصطلحات موضوعية: | Endoscopic retrograde cholangiopancreatography, Magnetic resonance cholangiopancreatography, Portal biliopathy, Portal cavernoma, Porto-systemic shunt, Gastroenterology |
| الوصف: | Portal biliopathy (PB) is defined as the presence of biliary abnormalities in patients with non-cirrhotic/non-neoplastic extrahepatic portal vein obstruction (EHPVO) and portal cavernoma (PC). The pathogenesis of PB is due to ab extrinseco compression of bile ducts by PC and/or to ischemic damage secondary to an altered biliary vascularization in EHPVO and PC. Although asymptomatic biliary abnormalities can be frequently seen by magnetic resonance cholangiopancreatography in patients with PC (77%-100%), only a part of these (5%-38%) are symptomatic. Clinical presentation includes jaundice, cholangitis, cholecystitis, abdominal pain, and cholelithiasis. In this subset of patients is required a specific treatment. Different therapeutic approaches aimed to diminish portal hypertension and treat biliary strictures are available. In order to decompress PC, surgical porto-systemic shunt or transjugular intrahepatic porto-systemic shunt can be performed, and treatment on the biliary stenosis includes endoscopic (Endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy, balloon dilation, stone extraction, stent placement) and surgical (bilioenteric anastomosis, cholecystectomy) approaches. Definitive treatment of PB often requires multiple and combined interventions both on vascular and biliary system. Liver transplantation can be considered in patients with secondary biliary cirrhosis, recurrent cholangitis or unsuccessful control of portal hypertension. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/28018098; info:eu-repo/semantics/altIdentifier/wos/WOS:000389848200004; volume:22; issue:45; firstpage:9909; lastpage:9920; numberofpages:12; journal:WORLD JOURNAL OF GASTROENTEROLOGY; http://hdl.handle.net/11577/3230426Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85002841004; http://www.wjgnet.com/1007-9327/journal/v22/i45/index.htm04Test |
| DOI: | 10.3748/wjg.v22.i45.9909 |
| الإتاحة: | https://doi.org/10.3748/wjg.v22.i45.9909Test http://hdl.handle.net/11577/3230426Test http://www.wjgnet.com/1007-9327/journal/v22/i45/index.htm04Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.D5270D0F |
| قاعدة البيانات: | BASE |
| DOI: | 10.3748/wjg.v22.i45.9909 |
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