دورية أكاديمية
Surgical Treatment of Spinal Meningiomas in the Elderly (≥75 Years): Which Factors Affect the Neurological Outcome? An International Multicentric Study of 72 Cases
| العنوان: | Surgical Treatment of Spinal Meningiomas in the Elderly (≥75 Years): Which Factors Affect the Neurological Outcome? An International Multicentric Study of 72 Cases |
|---|---|
| المؤلفون: | Capo G., Moiraghi A., Baro V., Tahhan N., Delaidelli A., Saladino A., Paun L., DiMeco F., Denaro L., Meling T. R., Tessitore E., Barrey C. Y. |
| المساهمون: | Capo, G., Moiraghi, A., Baro, V., Tahhan, N., Delaidelli, A., Saladino, A., Paun, L., Dimeco, F., Denaro, L., Meling, T. R., Tessitore, E., Barrey, C. Y. |
| بيانات النشر: | MDPI |
| سنة النشر: | 2022 |
| المجموعة: | Padua Research Archive (IRIS - Università degli Studi di Padova) |
| مصطلحات موضوعية: | elderly, functional disability, functional outcome, geriatric surgery, neurosurgery, quality of life, spinal cord, spinal meningiomas |
| الوصف: | (1) Background: With the increasing life expectancy in the Western world, an increasing number of old patients presents with spinal meningioma. Considering the benign nature of these tumors, the functional outcome remains of great importance, since more people reach old age in general conditions of well-being and satisfactory autonomy. (2) Methods: We conducted an international multicenter retrospective study to investigate demographic, clinical and radiological data in a population of elderly patients (≥75 years of age) undergoing surgery for SM from January 2000 to December 2020 in four European referral centers. The aim was to identify prognostic and predictive factors for a good postoperative functional outcome. (3) Results: 72 patients were included in the study. Complete tumor resection (Simpson I or II) was achieved in 67 (95.7%) cases. Intraoperative complications were reported in 7 (9.9%) patients while postoperative complications were found in 12 (16.7%). An excellent general postoperative status (McCormick I and II) was achieved in 65.3%. Overall, surgical resection had a good impact on patients’ functional outcome (86.1% either showing an improvement or maintaining a good preoperative status). Uni- and multivariate analyses found that both age and preoperative modified McCormick independently correlated with relative outcome (coeff = −0.058, p = 0.0251; coeff = 0.597, p < 0.0001) and with postoperative status (coeff = 0.058, p = 0.02507; coeff = 0.402, p = 0.00027), respectively. (4) Conclusions: Age and preoperative modified McCormick were found to be independent prognostic factors. Nevertheless, advanced age (≥75), per se, did not seem to contraindicate surgery, even in those with severe preoperative neurological deficits. The functional results sustain the need for surgical resection of SM in the elderly. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36230713; info:eu-repo/semantics/altIdentifier/wos/WOS:000866685000001; volume:14; issue:19; firstpage:4790; journal:CANCERS; https://hdl.handle.net/11577/3493303Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85139963186 |
| DOI: | 10.3390/cancers14194790 |
| الإتاحة: | https://doi.org/10.3390/cancers14194790Test https://hdl.handle.net/11577/3493303Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.1C68D9D5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/cancers14194790 |
|---|