دورية أكاديمية
Effectiveness of adding alarms to flash glucose monitoring in adults with type 1 diabetes under routine care
| العنوان: | Effectiveness of adding alarms to flash glucose monitoring in adults with type 1 diabetes under routine care |
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| المؤلفون: | Boscari F., Ferretto S., Cavallin F., Fadini G. P., Avogaro A., Bruttomesso D. |
| المساهمون: | Boscari, F., Ferretto, S., Cavallin, F., Fadini, G. P., Avogaro, A., Bruttomesso, D. |
| بيانات النشر: | Springer-Verlag Italia s.r.l. |
| سنة النشر: | 2022 |
| المجموعة: | Padua Research Archive (IRIS - Università degli Studi di Padova) |
| مصطلحات موضوعية: | Flash glucose monitoring-Free Style Libre 1 and 2, Glucose control, Psychological aspect, Time in range, Type 1 diabete, Adult, Blood Glucose, Blood Glucose Self-Monitoring, Human, Hypoglycemic Agent, Insulin, Diabetes Mellitus, Type 1, Hyperglycemia, Hypoglycemia |
| الوصف: | Aim: Whether glucose sensor alarms improve metabolic control and are accepted by individuals with diabetes is unclear. Here, we investigated whether switching from a standard flash glucose monitoring system (FGM1)to a systemequipped with hypo- and hyperglycemia alarms (FGM2) improves glycemic control and psychological outcomes in adults with type 1 diabetes (T1D). Methods: Subjects with T1D and > 4% of time in hypoglycemia or > 40% of time in hyperglycemia were studied while wearing FGM1 (4weeks) and after switching to FGM2 for 8weeks. The primary endpoint wasthe change in time in range (TIR 70–180mg/dl [3.9–10.0mmol/L])after4 weeks of FGM2 use. Time below range (TBR), time above range (TAR), mean glucose, coefficient of variation (CV), sensor scans, treatment satisfaction, and hypoglycemia fear were secondary outcomes. Results: We included 38 subjects aged 33.7 ± 12.6year. During 4weeks of FGM2 use, TIR increased from 52.8 to 57.0% (p = 0.001), TBR decreased from 6.2 to 3.4% (p < 0.0001) as did time < 54mg/dl (from 1.4 to 0.3%, p < 0.0001) and CV (from 39.6% to 36.1%, p < 0.0001). These changes were confirmed after 8weeks of FGM2 use. Treatment satisfaction improved and fear of hypoglycemia decreased. Subjects who had > 4% of time in hypoglycemia at baseline showed the greatest improvements in glucose control and treatment satisfaction. Conclusion: Switching from FGM1 to FGM2 improved TIR and treatment satisfaction and reduced fear of hypoglycemia. Participants who benefited most from switching from FGM1 to FGM2 were those prone to hypoglycemia. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35416537; info:eu-repo/semantics/altIdentifier/wos/WOS:000782324300001; volume:59; issue:7; firstpage:921; lastpage:928; numberofpages:8; journal:ACTA DIABETOLOGICA; http://hdl.handle.net/11577/3451486Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85128176279 |
| DOI: | 10.1007/s00592-022-01884-1 |
| الإتاحة: | https://doi.org/10.1007/s00592-022-01884-1Test http://hdl.handle.net/11577/3451486Test |
| رقم الانضمام: | edsbas.CE6D945D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00592-022-01884-1 |
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