دورية أكاديمية
Rates of Endoscopic Recurrence In Postoperative Crohn’s Disease Based on Anastomotic Techniques: A Systematic Review And Meta-Analysis
| العنوان: | Rates of Endoscopic Recurrence In Postoperative Crohn’s Disease Based on Anastomotic Techniques: A Systematic Review And Meta-Analysis |
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| المؤلفون: | Nardone, Olga Maria, Calabrese, Giulio, Barberio, Brigida, Giglio, Mariano Cesare, Castiglione, Fabiana, Luglio, Gaetano, Savarino, Edoardo, Ghosh, Subrata, Iacucci, Marietta |
| المساهمون: | Nardone, Olga Maria, Calabrese, Giulio, Barberio, Brigida, Giglio, Mariano Cesare, Castiglione, Fabiana, Luglio, Gaetano, Savarino, Edoardo, Ghosh, Subrata, Iacucci, Marietta |
| بيانات النشر: | OXFORD UNIV PRESS INC |
| سنة النشر: | 2023 |
| المجموعة: | Padua Research Archive (IRIS - Università degli Studi di Padova) |
| مصطلحات موضوعية: | Crohn’s disease, Kono-S anastomosi, conventional anastomosi, endoscopic recurrence, postoperative recurrence |
| الوصف: | Background: Patients with Crohn's disease (CD) after ileocolic resection may develop an endoscopic postoperative recurrence (ePOR) that reaches 40% to 70% of incidence within 6 months. Recently, there has been growing interest in the potential effect of anastomotic configurations on ePOR. Kono-S anastomosis has been proposed for reducing the risk of clinical and ePOR. Most studies have assessed the association of ileocolonic anastomosis and ePOR individually, while there is currently limited data simultaneously comparing several types of anastomosis. Therefore, we performed a systematic review and meta-analysis to assess the impact of different ileocolonic anastomosis on ePOR in CD.Methods: We searched PubMed and Embase from inception to January 2023 for eligible studies reporting the types of anastomoses and, based on these, the rate of endoscopic recurrence at >= 6 months. Studies were grouped by conventional anastomosis, including side-to-side, end-to-end, and end-to-side vs Kono-S, and comparisons were made between these groups. Pooled incidence rates of ePOR were computed using random-effect modelling.Results: Seventeen studies, with 2087 patients who underwent ileocolic resection for CD were included. Among these patients, 369 (17,7%) Kono-S anastomoses were performed, while 1690 (81,0%) were conventional ileocolic anastomosis. Endoscopic postoperative recurrence at >= 6 months showed a pooled incidence of 37.2% (95% CI, 27.7-47.2) with significant heterogeneity among the studies (P < .0001). In detail, patients receiving a Kono-S anastomosis had a pooled incidence of ePOR of 24.7% (95% CI, 6.8%-49.4%), while patients receiving a conventional anastomosis had an ePOR of 42.6% (95% CI, 32.2%-53.4%).Conclusions: Kono-S ileocolic anastomosis was more likely to decrease the risk of ePOR at >= 6 months compared with conventional anastomosis. Our findings highlight the need to implement the use of Kono-S anastomosis, particularly for difficult to treat patients. However, results from larger randomized ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37931290; info:eu-repo/semantics/altIdentifier/wos/WOS:001099874200001; journal:INFLAMMATORY BOWEL DISEASES; https://hdl.handle.net/11577/3505910Test |
| DOI: | 10.1093/ibd/izad252 |
| الإتاحة: | https://doi.org/10.1093/ibd/izad252Test https://hdl.handle.net/11577/3505910Test |
| رقم الانضمام: | edsbas.72CAD2F0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ibd/izad252 |
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