دورية أكاديمية

Nutritional state and energy balance in cirrhotic patients with or without hypermetabolism multicentre prospective study by the 'Nutritional Problems in Gastroenterology' section of the Italian Society of Gastroenterology (SIGE)

التفاصيل البيبلوغرافية
العنوان: Nutritional state and energy balance in cirrhotic patients with or without hypermetabolism multicentre prospective study by the 'Nutritional Problems in Gastroenterology' section of the Italian Society of Gastroenterology (SIGE)
المؤلفون: GUGLIELMI FW, PANELLA C, BUDA A, BUDILLON G, CLERICI C, CONTE D, FEDERICO A, GASBARRINI G, GUGLIELMI A, LOGUERCIO C, LOSCO A, MAZZUOLI S, MERLI M, MINGRONE G, MORELLI A, NARDONE G, ZOLI G, FRANCAVILLA A., CAREGARO NEGRIN, LORENZA, MARTINES, DIEGO
المساهمون: Guglielmi, Fw, Panella, C, Buda, A, Budillon, G, CAREGARO NEGRIN, Lorenza, Clerici, C, Conte, D, Federico, A, Gasbarrini, G, Guglielmi, A, Loguercio, C, Losco, A, Martines, Diego, Mazzuoli, S, Merli, M, Mingrone, G, Morelli, A, Nardone, G, Zoli, G, Francavilla, A.
بيانات النشر: Editrice Gastroenterologica Italiana S.r.l.
سنة النشر: 2005
المجموعة: Padua Research Archive (IRIS - Università degli Studi di Padova)
مصطلحات موضوعية: Hypermetabolism, Liver cirrhosis, Nutrient intake, Nutritional state, Physical activity
الوصف: BACKGROUND AND AIMS: A total of 334 stable, compensated cirrhotic patients admitted to 10 Italian Gastroenterology Units were included in a prospective study to evaluate nutritional state and energy balance in liver cirrhosis. MATERIALS AND METHODS: Nutritional state and calorie intake were examined in the total population, while adequacy of calorie intake versus measured total energy expenditure was evaluated in a comparable subpopulation and in 40 matched controls, by computing the energy balance. RESULTS: Our data demonstrated that: (i) malnutrition was present in 25% of the total patients and significantly correlated with the Child's group (A=16%; B=25%; C=44%); (ii) the type of malnutrition is influenced by mBEE: normometabolic patients exhibit a significant (p<0.005) reduction of mid-arm fat area while both hypermetabolic and hypometabolic patients show a significant (p<0.005) decline in kg of free fat mass; (iii) normometabolic and hypometabolic patients have a negative energy balance, due to a high level of physical activity (127+/-14 kJ) in the first group and a reduced energy intake/kg body weight (102+/-12 kJ) in the second; (iv) hypermetabolic patients have a positive energy balance due to decreased daily physical activity/kg body weight (108+/-28 kJ); (v) malnourished and normometabolic patients eat a significantly (p<0.05) reduced percentage of protein whereas malnourished and hypermetabolic patients eat a significantly increased percentage of fat (p<0.05). CONCLUSION: Although multivariate regression analysis confirms that the Child-Pugh's score is a better independent predictor of malnutrition, the measure of REE, TEE, calorie intake and energy balance need to be routinely performed in cirrhotic patients, in order to recognise hypermetabolic and hypometabolic patients (approximately 30%) in whom the nutritional and metabolic parameters are indispensable as a basis for designing and prescribing personalised nutritional strategies that can treat muscle malnutrition and thus improve the ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: STAMPA
اللغة: unknown
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/15978878; info:eu-repo/semantics/altIdentifier/wos/WOS:000231965200008; volume:37; firstpage:681; lastpage:688; numberofpages:8; journal:DIGESTIVE AND LIVER DISEASE; http://hdl.handle.net/11577/2469928Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-33644821302; http://www.ncbi.nlm.nih.gov/pubmed/15978878Test; http://www.sciencedirect.com/science/article/pii/S159086580500188XTest
DOI: 10.1016/j.dld.2005.03.010
الإتاحة: https://doi.org/10.1016/j.dld.2005.03.010Test
http://hdl.handle.net/11577/2469928Test
http://www.ncbi.nlm.nih.gov/pubmed/15978878Test
http://www.sciencedirect.com/science/article/pii/S159086580500188XTest
رقم الانضمام: edsbas.FF819B08
قاعدة البيانات: BASE