دورية أكاديمية
ニガウリ抽出物の血糖降下作用に関する文献的考察 ; Hypoglycemic activity of Momordica charantia (bitter melon)
| العنوان: | ニガウリ抽出物の血糖降下作用に関する文献的考察 ; Hypoglycemic activity of Momordica charantia (bitter melon) |
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| المؤلفون: | Mankura, Mitsumasa, Noda, Yasuko, Mori, Akitane |
| المصدر: | 岡山医学会雑誌 |
| بيانات النشر: | 岡山医学会 |
| سنة النشر: | 2016 |
| المجموعة: | Okayama University Scientific Achievement Repository / 岡山大学学術成果リポジトリ |
| مصطلحات موضوعية: | ニガウリ (bitter melon), Momordica charantia, 糖尿病 (diabetes mellitus), 酸化ストレス (oxidative stress) |
| الوصف: | Diabetes mellitus (DM) represents a global health and economical problem. Many patients with DM in Asia, South America, India and East Africa have traditionally used the water extract of unripe fruits of Momordica charantia (bitter melon) as some form of complementary and alternative medicine. Studies of laboratory animals have shown the beneficial blood-glucose lowering and anti-diabetic effects of this remedy. Some oral components that bring lower blood glucose level have been isolated : charantin (sterol glycosides), charantin (polypeptide) and cucurbine-type triterpenes. Part of their actions are related to AMP-activated kinase and repression of the oxidative stress that is increased in DM. Most clinical reports are not fully convincing due to the lack of randomized control studies. The present article reviews the pharmacological and clinical effects of bitter melon with special emphasis on the anti-diabetic effects, and some effects that would require caution in the context of human trials. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Japanese |
| تدمد: | 0030-1558 |
| العلاقة: | https://ousar.lib.okayama-u.ac.jp/files/public/4/48131/20160528093129245546/124_15.pdfTest; AN00032489; https://ousar.lib.okayama-u.ac.jp/48131Test |
| الإتاحة: | https://doi.org/10.4044/joma.124.15Test https://ousar.lib.okayama-u.ac.jp/files/public/4/48131/20160528093129245546/124_15.pdfTest https://ousar.lib.okayama-u.ac.jp/48131Test |
| حقوق: | Copyright (c) 2012 岡山医学会 |
| رقم الانضمام: | edsbas.746089B7 |
| قاعدة البيانات: | BASE |
| تدمد: | 00301558 |
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