Cutaneous lymphoblastic lymphoma of putative plasmacytoid denbritic cell-precursor origin; 2 cases

التفاصيل البيبلوغرافية
العنوان: Cutaneous lymphoblastic lymphoma of putative plasmacytoid denbritic cell-precursor origin; 2 cases
المؤلفون: Momoi, Akihito, Toba, Ken, Kawai, Kazuhiro, Tsuchiyama, Junjiro, Suzuki, Noriatsu, Yano, Toshio, Uesugi, Yumiko, Takahashi, Masuhiro, Aizawa, Yoshifusa
بيانات النشر: Elsevier
سنة النشر: 2002
المجموعة: Niigata University Academic Repository (NUAR) / 新潟大学学術リポジトリ
مصطلحات موضوعية: lymphoblastic lymphoma, plasmacytoid dendritic cell, cutaneous lymphoma, gene rearrangement, chromosome translocation, leukemic transformation
الوصف: Although the neoplasm of relatively mature type pDC was recently reported, that of pDC-precursor has not yet been defined. We experienced 2 elderly male Japanese patients with reddish skin tumors. The histology of the tumors in both patients showed TdT-positive LBL. The pathological cells did not express T-, B- or NK-markers, and no rearranged bands were shown for Ig-JH, TCR-Cβ, Jγ, Jδ1, and c-myc. In addition, no EBV-derived DNA was detected in either case. The cells were CD45, CD43, CD74, CD10 and HLA-DR positive in both cases, and one of the cases showed CD4, CD36, CD54, CD58 and CD86-positive plasmacytoid lymphoblasts, which appeared to be compatible with intermediate cells between human bone marrow lymphoid precursors and mature lymphoid dendritic cells. The cutaneous LBL in the 2 cases may, therefore, have been of pDC-precursor origin. ; journal article
نوع الوثيقة: other/unknown material
وصف الملف: application/pdf
اللغة: English
تدمد: 0145-2126
العلاقة: http://doi.org/10.1016/s0145-2126Test(01)00198-9; Leukemia Research; 26; 693; 698; AA00716755; https://niigata-u.repo.nii.ac.jp/record/2155/files/24_0017.pdfTest
الإتاحة: https://doi.org/10.1016/s0145-2126Test(01)00198-9
https://niigata-u.repo.nii.ac.jp/record/2155/files/24_0017.pdfTest
حقوق: Elsevier Ltd
رقم الانضمام: edsbas.797405D
قاعدة البيانات: BASE