التفاصيل البيبلوغرافية
| العنوان: |
Expression of the Spot 35/calbindin D 28k gene ; Spot 35/calbindin D 28k遺伝子の解析 |
| المؤلفون: |
桑野, 良三, 117904 |
| بيانات النشر: |
新潟医学会 |
| سنة النشر: |
1994 |
| المجموعة: |
Niigata University Academic Repository (NUAR) / 新潟大学学術リポジトリ |
| مصطلحات موضوعية: |
cerebellum, calcium binding protein, transcription, vitamin D response element, 小脳, カルシウム結合蛋白, 転写, ビタミンD応答配列 |
| الوصف: |
Spot 35 protein was first discovered from the cerebellum as a specific protein. Immunohistochemistry demonstrated wide distribution of this protein in the Purkinje cells, intestine, sensory organs and kidney. cDNA cloning and nucleotide sequence showed that Spot 35 protein is identical with calbindin D 28k, a vitamin D dependent calcium binding protein. Two vitamin D response elements (pDRE and dDRE) were found in the 5' upstream region of the Spot 35/Calbindin D 28k gene. Promoter activities were determined by using luciferase as a reporter gene in MDBK cells which produced endogenously Spot 35/Calbindin D 28k. Transcription of the chimeric gene containing the pDRE was enhanced by 1, 25 (OH)_2D_3 stimulation in an orientation-dependent fashion. ; departmental bulletin paper |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/pdf |
| اللغة: |
Japanese |
| تدمد: |
00290440 |
| العلاقة: |
新潟医学会雑誌; 11; 108; 798; 803; AN00182415; https://niigata-u.repo.nii.ac.jp/record/18891/files/108Test(11)_798-803.pdf |
| الإتاحة: |
https://niigata-u.repo.nii.ac.jp/record/18891/files/108Test(11)_798-803.pdf |
| رقم الانضمام: |
edsbas.F1433913 |
| قاعدة البيانات: |
BASE |
