دورية أكاديمية

The correlation between iodine nutrition and autoimmunity among hyperthyroid goiter patients in tertiary care hospital of Tamil Nadu

التفاصيل البيبلوغرافية
العنوان: The correlation between iodine nutrition and autoimmunity among hyperthyroid goiter patients in tertiary care hospital of Tamil Nadu
المؤلفون: Suresh Pichandi, Sivakumar J, Ganesh V, Janakiraman P, Ramadevi K
المصدر: Asian Journal of Medical Sciences; Vol. 13 No. 7 (2022); 82-86 ; 2091-0576 ; 2467-9100
بيانات النشر: Asian Journal of Medical Sciences Pokhara
سنة النشر: 2022
المجموعة: Nepal Journals Online (NepJOL)
مصطلحات موضوعية: Goiter, Iodine-induced hyperthyroidism, Thyroiditis, Thyrotoxicosis, Urinary iodine excretion
الوصف: Background: Iodine is a trace element that is essential for the formation of thyroid hormones. It is essential for the human life’s growth and development. The thyroid gland size and functions affected by deficient or excessive intake of iodine. Iodine excess intake was found to associating with iodine-induced hyperthyroidism (IIH) and autoimmune thyroiditis. Aims and Objectives: The present study was to find the hyperthyroid goiter patient nutritional status by urinary iodine excretion (UIE) measurement and correlate them with thyroid hormone and thyroid autoantibodies. Materials and Methods: In this study, 100 adult hyperthyroid goiter ssubjects and 100 apparently normal adult subjects were conveniently recruited in this study.Urinary iodine estimation and serum TSH, fT4, fT3, AMA, and ATG were estimated,which were estimated for case and control groups. Results: The hyperthyroid goiter patient mean UIE concentration was 278.98 μg/L and 68% of excess UIE which was found. There was significant difference in the UIE between the hyperthyroid goiter patient and control (P<0.001). The following types of goiter, based on palpation, were identified among the 100 hyperthyroid patients: Grade I – 4 %, Grade II – 63%, and Grade III – 33%. There were elevated serum AMA levelswith positive correlation of excess iodine for hyperthyroid goiter patient. Conclusion: In this study, there were excess UIEs among patients; hence, these associated complications, namely, benign goiter (14%), thyroiditis (43%), cancer of thyroid (4%), and thyrotoxicosis (39%) were observed.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: https://www.nepjol.info/index.php/AJMS/article/view/43645/34320Test; https://www.nepjol.info/index.php/AJMS/article/view/43645Test
الإتاحة: https://www.nepjol.info/index.php/AJMS/article/view/43645Test
حقوق: Copyright (c) 2022 Asian Journal of Medical Sciences ; https://creativecommons.org/licenses/by-nc/4.0Test
رقم الانضمام: edsbas.87C1FF5E
قاعدة البيانات: BASE