يعرض 1 - 10 نتائج من 36 نتيجة بحث عن '"cadherin"', وقت الاستعلام: 0.68s تنقيح النتائج
  1. 1
    دورية أكاديمية

    المؤلفون: 王培任, Wang, Pei-Jen

    المساهمون: 李士傑, 臺灣大學:漁業科學研究所

    وصف الملف: 998574 bytes; application/pdf

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Batista, T., de, S.G., Suput, J.S., Rahmani, R., and Suput, D., 2003. Microcystin-LR causes the collapse of actin filaments in primary human hepatocytes. Aquat. Toxicol. 65, 85-91. Becker, K.A. and Hart, N.H., 1996. The cortical actin cytoskeleton of unactivated zebrafish eggs: spatial organization and distribution of filamentous actin, nonfilamentous actin, and myosin-II. Mol. Reprod. Dev. 43, 536-547. Best, J.H., Pflugmacher, S., Wiegand, C., Eddy, F.B., Metcalf, J.S., and Codd, G.A., 2002. Effects of enteric bacterial and cyanobacterial lipopolysaccharides, and of microcystin-LR, on glutathione S-transferase activities in zebra fish (Danio rerio). Aquat. Toxicol. 60, 223-231. Botha, N., Gehringer, M.M., Downing, T.G., van, d., V, and Shephard, E.G., 2004a. The role of microcystin-LR in the induction of apoptosis and oxidative stress in CaCo2 cells. Toxicon 43, 85-92. Botha, N., van, d., V, Downing, T.G., Shephard, E.G., and Gehringer, M.M., 2004b. The effect of intraperitoneally administered microcystin-LR on the gastrointestinal tract of Balb/c mice. Toxicon 43, 251-254. Brautigan, D.L., 1994. Protein phosphatases. Recent Prog. Horm. Res. 49, 197-214. Brautigan, D.L., 1995. Flicking the switches: phosphorylation of serine/threonine protein phosphatases. Semin. Cancer Biol. 6, 211-217. Carmichael, W.W., 1992. Cyanobacteria secondary metabolites--the cyanotoxins. J. Appl. Bacteriol. 72, 445-459. Carmichael, W.W., 1994. The toxins of cyanobacteria. Sci. Am. 270, 78-86. Chong, M.W., Gu, K.D., Lam, P.K., Yang, M., and Fong, W.F., 2000. Study on the cytotoxicity of microcystin-LR on cultured cells. Chemosphere 41, 143-147. Chua, K.L. and Lim, T.M., 2000. Type I and type II cytokeratin cDNAs from the zebrafish (Danio rerio) and expression patterns during early development. Differentiation 66, 31-41. Cohen, P., 1989. The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58, 453-508. Conrad, M., Lemb, K., Schubert, T., and Markl, J., 1998. Biochemical identification and tissue-specific expression patterns of keratins in the zebrafish Danio rerio. Cell Tissue Res. 293, 195-205. Contin, M.A., Purro, S.A., Bisig, C.G., Barra, H.S., and Arce, C.A., 2003. Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules. Eur. J. Biochem. 270, 4921-4929. Daggett, D.F., Boyd, C.A., Gautier, P., Bryson-Richardson, R.J., Thisse, C., Thisse, B., Amacher, S.L., and Currie, P.D., 2004. Developmentally Restricted Actin-Regulatory Molecules Control Morphogenetic Cell Movements in the Zebrafish Gastrula. Curr. Biol. 14, 1632-1638. Dawson, R.M., 1998. The toxicology of microcystins. Toxicon 36, 953-962. de Figueiredo, D.R., Azeiteiro, U.M., Esteves, S.M., Goncalves, F.J., and Pereira, M.J., 2004. Microcystin-producing blooms--a serious global public health issue. Ecotoxicol. Environ. Saf 59, 151-163. Ding, W.X., Shen, H.M., Shen, Y., Zhu, H.G., and Ong, C.N., 1998a. Microcystic cyanobacteria causes mitochondrial membrane potential alteration and reactive oxygen species formation in primary cultured rat hepatocytes. Environ. Health Perspect. 106, 409-413. Ding, W.X., Shen, H.M., Zhu, H.G., and Ong, C.N., 1998b. Studies on oxidative damage induced by cyanobacteria extract in primary cultured rat hepatocytes. Environ. Res. 78, 12-18. Ding, W.X., Shen, H.M., and Ong, C.N., 2000. Microcystic cyanobacteria extract induces cytoskeletal disruption and intracellular glutathione alteration in hepatocytes. Environ. Health Perspect. 108, 605-609. Ding, W.X., Shen, H.M., and Ong, C.N., 2001. Critical role of reactive oxygen species formation in microcystin-induced cytoskeleton disruption in primary cultured hepatocytes. J. Toxicol. Environ. Health A 64, 507-519. Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C., 1996. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123, 37-46. Falconer, I.R. and Yeung, D.S., 1992. Cytoskeletal changes in hepatocytes induced by Microcystis toxins and their relation to hyperphosphorylation of cell proteins. Chem. Biol. Interact. 81, 181-196. Falconer, I.R., 1999. An overview of problems caused by toxic blue-green algae (cyanobacteria) in drinking and recreational water. Environ. Toxicol. 14, 5-12. Fischer, W.J. and Dietrich, D.R., 2000. Pathological and Biochemical Characterization of Microcystin-Induced Hepatopancreas and Kidney Damage in Carp (Cyprinus carpio). Toxicol. Appl. Pharmacol. 164, 73-81. Frangez, R., Zuzek, M.C., Mrkun, J., Suput, D., Sedmak, B., and Kosec, M., 2003. Microcystin-LR affects cytoskeleton and morphology of rabbit primary whole embryo cultured cells in vitro. Toxicon 41, 999-1005. Garcia, A., Cayla, X., Guergnon, J., Dessauge, F., Hospital, V., Rebollo, M.P., Fleischer, A., and Rebollo, A., 2003. Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis. Biochimie 85, 721-726. Gehringer, M.M., 2004. Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response. FEBS Letters 557, 1-8. Gotz, J., Probst, A., Mistl, C., Nitsch, R.M., and Ehler, E., 2000. Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development. Mech. Dev. 93, 83-93. Gumbiner, B.M., 1995. Signal transduction of beta-catenin. Curr. Opin. Cell Biol. 7, 634-640. Guzman, R.E., Solter, P.F., and Runnegar, M.T., 2003. Inhibition of nuclear protein phosphatase activity in mouse hepatocytes by the cyanobacterial toxin microcystin-LR. Toxicon 41, 773-781. Honkanen, R.E., Zwiller, J., Moore, R.E., Daily, S.L., Khatra, B.S., Dukelow, M., and Boynton, A.L., 1990. Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J. Biol. Chem. 265, 19401-19404. Horsfield, J., Ramachandran, A., Reuter, K., LaVallie, E., Collins-Racie, L., Crosier, K., and Crosier, P., 2002. Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development. Mech. Dev. 115, 15-26. Humpage, A.R. and Falconer, I.R., 1999. Microcystin-LR and liver tumor promotion: Effects on cytokinesis, ploidy, and apoptosis in cultured hepatocytes. Environ. Toxicol. 14, 61-75. Hunter, T., 1995. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80, 225-236. Imanishi, S. and Harada, K.i., 2004. Proteomics approach on microcystin binding proteins in mouse liver for investigation of microcystin toxicity. Toxicon 43, 651-659. Imboden, M., Goblet, C., Korn, H., and Vriz, S., 1997. Cytokeratin 8 is a suitable epidermal marker during zebrafish development. Comptes Rendus de l'Academie des Sciences - Series III - Sciences de la Vie 320, 689-700. Ito, E., Kondo, F., Terao, K., and Harada, K., 1997. Neoplastic nodular formation in mouse liver induced by repeated intraperitoneal injections of microcystin-LR. Toxicon 35, 1453-1457. Ito, E., Kondo, F., and Harada, K.i., 2001. Intratracheal administration of microcystin-LR, and its distribution. Toxicon 39, 265-271. Jacquet, C., Thermes, V., Luze, A.d., Puiseux-Dao, S., Bernard, C., Joly, J.S., Bourrat, F., and Edery, M., 2004. Effects of microcystin-LR on development of medaka fish embryos (Oryzias latipes). Toxicon 43, 141-147. Keil, C., Forchert, A., Fastner, J., Szewzyk, U., Rotard, W., Chorus, I., and Kratke, R., 2002. Toxicity and microcystin content of extracts from a Planktothrix bloom and two laboratory strains. Water Res. 36, 2133-2139. Kimmel, C.B., Ballard, W.W., Kimmel, S.R., Ullmann, B., and Schilling, T.F., 1995. Stages of embryonic development of the zebrafish. Dev. Dyn. 203, 253-310. Ku, N.O., Michie, S.A., Soetikno, R.M., Resurreccion, E.Z., Broome, R.L., and Omary, M.B., 1998. Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J. Cell Biol. 143, 2023-2032. Lankoff, A. and Kolataj, A., 2000. Influence of microcystine-YR and nodularin on the activity of some glucosidases in mouse liver. Toxicology 146, 177-185. Lawton, L.A. and Edwards, C., 2001. Purification of microcystins. J. Chromatogr. A 912, 191-209. Lee, T.H., Chen, Y.M., and Chou, H.N., 1998. First report of microcystins in Taiwan. Toxicon 36, 247-255. Leung, C.F., Webb, S.E., and Miller, A.L., 2000. On the mechanism of ooplasmic segregation in single-cell zebrafish embryos. Dev. Growth Differ. 42, 29-40. Li, X., Liu, Y., and Song, L., 2001. Cytological alterations in isolated hepatocytes from common carp (Cyprinus carpio L.) exposed to microcystin-LR. Environ. Toxicol. 16, 517-522. Li, X., Liu, Y., Song, L., and Liu, J., 2003. Responses of antioxidant systems in the hepatocytes of common carp (Cyprinus carpio L.) to the toxicity of microcystin-LR. Toxicon 42, 85-89. Liu, Q., Babb, S.G., Novince, Z.M., Doedens, A.L., Marrs, J., and Raymond, P.A., 2001. Differential expression of cadherin-2 and cadherin-4 in the developing and adult zebrafish visual system. Vis. Neurosci. 18, 923-933. Liu, Y., Song, L., Li, X., and Liu, T., 2002. The toxic effects of microcystin-LR on embryo-larval and juvenile development of loach, Misguruns mizolepis Gunthe. Toxicon 40, 395-399. MacKintosh, R.W., Dalby, K.N., Campbell, D.G., Cohen, P.T.W., Cohen, P., and MacKintosh, C., 1995. The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1. FEBS Letters 371, 236-240. Magalhaes, V.F., Marinho, M.M., Domingos, P., Oliveira, A.C., Costa, S.M., Azevedo, L.O., and Azevedo, S.M.F.O., 2003. Microcystins (cyanobacteria hepatotoxins) bioaccumulation in fish and crustaceans from Sepetiba Bay (Brasil, RJ). Toxicon 42, 289-295. Malbrouck, C., Trausch, G., Devos, P., and Kestemont, P., 2003. Hepatic accumulation and effects of microcystin-LR on juvenile goldfish Carassius auratus L. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 135, 39-48. Malbrouck, C., Trausch, G., Devos, P., and Kestemont, P., 2004. Effect of microcystin-LR on protein phosphatase activity in fed and fasted juvenile goldfish Carassius auratus L. Toxicon 43, 295-301. McDermott, C.M., Nho, C.W., Howard, W., and Holton, B., 1998. The cyanobacterial toxin, microcystin-LR, can induce apoptosis in a variety of cell types. Toxicon 36, 1981-1996. Mikhailov, A., Harmala-Brasken, A.S., Hellman, J., Meriluoto, J., and Eriksson, J.E., 2003. Identification of ATP-synthase as a novel intracellular target for microcystin-LR. Chem. Biol. Interact. 142, 223-237. Nagafuchi, A. and Takeichi, M., 1989. Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regul. 1, 37-44. Nelson, W.J. and Nusse, R., 2004. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303, 1483-1487. Nishiwaki-Matsushima, R., Ohta, T., Nishiwaki, S., Suganuma, M., Kohyama, K., Ishikawa, T., Carmichael, W.W., and Fujiki, H., 1992. Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J. Cancer Res. Clin. Oncol. 118, 420-424. Oberemm, A., Fastner, J., and Steinberg, C.E.W., 1997. Effects of microcystin-LR and cyanobacterial crude extracts on embryo-larval development of zebrafish (Danio rerio). Water Research 31, 2918-2921. Oberemm, A., Becker, J., Codd, G.A., and Steinberg, C., 1999. Effects of cyanobacterial toxins and aqueous crude extracts of cyanobacteria on the development of fish and amphibians. Environ. Toxicol. 14, 77-88. Ohta, T., Nishiwaki, R., Yatsunami, J., Komori, A., Suganuma, M., and Fujiki, H., 1992. Hyperphosphorylation of cytokeratins 8 and 18 by microcystin-LR, a new liver tumor promoter, in primary cultured rat hepatocytes. Carcinogenesis 13, 2443-2447. Pflugmacher, S., Wiegand, C., Oberemm, A., Beattie, K.A., Krause, E., Codd, G.A., and Steinberg, C.E., 1998. Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication. Biochim. Biophys. Acta 1425, 527-533. Pietsch, C., Wiegand, C., Ame, M.V., Nicklisch, A., Wunderlin, D., and Pflugmacher, S., 2001. The effects of a cyanobacterial crude extract on different aquatic organisms: evidence for cyanobacterial toxin modulating factors. Environ. Toxicol. 16, 535-542. Runnegar, M., Berndt, N., Kong, S.M., Lee, E.Y.C., and Zhang, L.F., 1995. In Vivo and in Vitro Binding of Microcystin to Protein Phosphatase 1 and 2A. Biochem. Biophys. Res. Commun. 216, 162-169. Runnegar, M.T., Gerdes, R.G., and Falconer, I.R., 1991. The uptake of the cyanobacterial hepatotoxin microcystin by isolated rat hepatocytes. Toxicon 29, 43-51. Schaffeld, M., Knappe, M., Hunzinger, C., and Markl, J., 2003. cDNA sequences of the authentic keratins 8 and 18 in zebrafish. Differentiation 71, 73-82. Serres, M., Grangeasse, C., Haftek, M., Durocher, Y., Duclos, B., and Schmitt, D., 1997. Hyperphosphorylation of [beta]-Catenin on Serine-Threonine Residues and Loss of Cell-Cell Contacts Induced by Calyculin A and Okadaic Acid in Human Epidermal Cells. Exp. Cell Res. 231, 163-172. Shapiro, L., Fannon, A.M., Kwong, P.D., Thompson, A., Lehmann, M.S., Grubel, G., Legrand, J.F., ls-Nielsen, J., Colman, D.R., and Hendrickson, W.A., 1995. Structural basis of cell-cell adhesion by cadherins. Nature 374, 327-337. Solnica-Krezel, L., Stemple, D.L., Mountcastle-Shah, E., Rangini, Z., Neuhauss, S.C., Malicki, J., Schier, A.F., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., and Driever, W., 1996. Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development 123, 67-80. Suchy, F.J., 1993. Hepatocellular transport of bile acids. Semin. Liver Dis. 13, 235-247. Takeichi, M., 1995. Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol. 7, 619-627. Tamura, S., Hanada, M., Ohnishi, M., Katsura, K., Sasaki, M., and Kobayashi, T., 2002. Regulation of stress-activated protein kinase signaling pathways by protein phosphatases. Eur. J. Biochem. 269, 1060-1066. Teneva, I., Asparuhova, D., Dzhambazov, B., Mladenov, R., and Schirmer, K., 2003. The freshwater cyanobacterium Lyngbya aerugineo-coerulea produces compounds toxic to mice and to mammalian and fish cells. Environ. Toxicol. 18, 9-20. Theiss, W.C., Carmichael, W.W., Wyman, J., and Bruner, R., 1988. Blood pressure and hepatocellular effects of the cyclic heptapeptide toxin produced by the freshwater cyanobacterium (blue-green alga) Microcystis aeruginosa strain PCC-7820. Toxicon 26, 603-613. Toivola, D.M., Goldman, R.D., Garrod, D.R., and Eriksson, J.E., 1997. Protein phosphatases maintain the organization and structural interactions of hepatic keratin intermediate filaments. J. Cell Sci. 110 ( Pt 1), 23-33. Toivola, D.M., Omary, M.B., Ku, N.O., Peltola, O., Baribault, H., and Eriksson, J.E., 1998. Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity. Hepatology 28, 116-128. Toivola, D.M. and Eriksson, J.E., 1999. Toxins affecting cell signalling and alteration of cytoskeletal structure. Toxicol. In Vitro. 13, 521-530. Xie, L., Xie, P., Ozawa, K., Honma, T., Yokoyama, A., and Park, H.D., 2004. Dynamics of microcystins-LR and -RR in the phytoplanktivorous silver carp in a sub-chronic toxicity experiment. Environ. Pollut. 127, 431-439. Yamashita, K., Yasuda, H., Pines, J., Yasumoto, K., Nishitani, H., Ohtsubo, M., Hunter, T., Sugimura, T., and Nishimoto, T., 1990. Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J. 9, 4331-4338. Zalik, S.E., Lewandowski, E., Kam, Z., and Geiger, B., 1999. Cell adhesion and the actin cytoskeleton of the enveloping layer in the zebrafish embryo during epiboly. Biochem. Cell Biol. 77, 527-542. Zambrano, F. and Canelo, E., 1996. Effects of microcystin-lr on the partial reactions of the Na+---K+ pump of the gill of carp (Cyprinus carpio linneo). Toxicon 34, 451-458. Zegura, B., Lah, T.T., and Filipic, M., 2004. The role of reactive oxygen species in microcystin-LR-induced DNA damage. Toxicology 200, 59-68.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/59358Test; http://ntur.lib.ntu.edu.tw/bitstream/246246/59358/1/ntu-94-R91243014-1.pdfTest

  2. 2
    دورية أكاديمية
  3. 3
    دورية أكاديمية

    المؤلفون: 蔡沛勳, Tsai, Pei-Hsun

    المساهمون: 李明亭, 臺灣大學:生化科學研究所

    مصطلحات موضوعية: 癌症, 轉移, 附著蛋白, A431, invasion, EMT, cadherin, β-catenin, FGFR1

    العلاقة: Aberle, H., H. Schwartz, H. Hoschuetzky, and R. Kemler. 1996. Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to alpha-catenin. J Biol Chem. 271:1520-1526. Albini, A., Y. Iwamoto, H.K. Kleinman, G.R. Martin, S.A. Aaronson, J.M. Kozlowski, and R.N. McEwan. 1987. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res. 47:3239-3245. Bernards, R., and R.A. Weinberg. 2002. A progression puzzle. Nature. 418:823. Berx, G., A.M. Cleton-Jansen, K. Strumane, W.J. de Leeuw, F. Nollet, F. van Roy, and C. Cornelisse. 1996. E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene. 13:1919-1925. Bienz, M. 2005. beta-Catenin: a pivot between cell adhesion and Wnt signalling. Curr Biol. 15:R64-67. Birchmeier, W., and J. Behrens. 1994. 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