التفاصيل البيبلوغرافية
العنوان: |
Shya, a Membrane Protein for Proper Septation of Hyphae in Streptomyces |
المؤلفون: |
鄧述諄, TENG, SHU-CHUN |
المساهمون: |
微生物學科所 |
سنة النشر: |
2006 |
المجموعة: |
National Taiwan University Institutional Repository (NTUR) |
مصطلحات موضوعية: |
Amino Acid Sequence, Cell Proliferation, Cell Size, Hyphae/ metabolism/ ultrastructure, Membrane Proteins/analysis/ chemistry/ metabolism, Molecular Sequence Data |
الوصف: |
The life cycle of Streptomyces involves the formation of filamentous substrate and aerial hyphae. Following cessation of growth of an aerial hypha, multiple septation occurs at the tip to produce a chain of unigenomic spores. A gene, shyA, which influences several aspects of this growth, was isolated and partially characterized in Streptomyces coelicolor. The gene product is a representative of a well- conserved family of small actinomycete proteins. The shyA mutant sporulates normally but displays hyper septum formation and altered spore-chain morphology. Biochemical separation experiments and immunofluorescence staining demonstrated that the shyA gene product locates at cell membranes. Moreover, yeast two-hybrid screen and GST-pull- down assay showed that ShyA can interact with itself. Altogether, ShyA belongs to a new family of membrane- associated proteins which plays a role in morphological differentiation in actinomycetes. |
نوع الوثيقة: |
other/unknown material |
اللغة: |
English |
العلاقة: |
BIOCHEM BIOPHYS RES COMMUN v.343 n.2 pp.369-377; http://ntur.lib.ntu.edu.tw/handle/246246/94353Test |
الإتاحة: |
http://ntur.lib.ntu.edu.tw/handle/246246/94353Test |
رقم الانضمام: |
edsbas.3F1B573A |
قاعدة البيانات: |
BASE |