التفاصيل البيبلوغرافية
| العنوان: |
Waist-to-Hip Ratio Correlates with Homocysteine Levels in Male Patients with Coronary Artery Disease |
| المؤلفون: |
林彥宏, 鮑冠吟, 楊偉勛, 吳允升, 陳裕仁, 林郁里, 蔡維珊, 蔡宜蓉, 高純綉, 黃瑞仁, LIN, YEN-HUNG, PAO, KUAN-YIN, YANG, WEI-SHIUNG, WU, VIN-CENT, CHEN, YU-JEN, LIN, YU-LI, TSAI, WEI-SHAN, TSAI, I-JUNG, GAU, CHURN-SHIOUH, HWANG, JUEY-JEN |
| المساهمون: |
內科部 |
| سنة النشر: |
2008 |
| المجموعة: |
National Taiwan University Institutional Repository (NTUR) |
| مصطلحات موضوعية: |
body mass index (BMI), coronary artery disease (CAD), homocysteine, waist-to-hip ratio (WHR) |
| الوصف: |
Background: Obesity and homocysteine are important risk factors for cardiovascular disease. The relation between pattern of obesity and homocysteine is unclear. The objective of this study was to investigate the relation between pattern of obesity and plasma total homocysteine ( tHcy) level in male patients with coronary artery disease ( CAD). Methods: A total of 63 male patients (mean age 66.2 years) with angiographically documented CAD were enrolled. Overnight fasting blood samples were measured for plasma tHcy, serum folic acid and serum vitamin B-12 levels. Anthropometric measurements included waist-to-hip ratio (WHR ) and body mass index (BMI). Results: The mean WHIR was 0.90 +/- 0.05, mean BMI 24.6 +/- 3.3 kg/m(2) and the mean plasma tHcy level 11.6 +/- 3.2 mu mol/L. In univariate analysis, plasma tHcy level correlated significantly with serum vitamin B12 level, serum folic acid level, WHR, estimated creatinine clearance, aspirin use and fibrate use. There was no significant association between plasma tHcy level and BMI. In multivariate analysis, only WHR (beta-value 22.263, p < 0.001), serum level of vitamin B-12 (beta -value-0.004, p =0.003), estimated creatinine clearance (beta-value -4.154 , p=0.003) and use of fibrates (beta-value 2.307, p=0.031) were independent predictors of plasma tHcy level. Conclusions: WHR, but not BMI , is a strong independent predictor of plasma tHcy level in male patients with CAD. |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
English |
| العلاقة: |
CLINICAL CHEMISTRY AND LABORATORY MEDICINE v.46 n.1 pp.125-130; http://ntur.lib.ntu.edu.tw/handle/246246/233589Test |
| الإتاحة: |
http://ntur.lib.ntu.edu.tw/handle/246246/233589Test |
| رقم الانضمام: |
edsbas.70275078 |
| قاعدة البيانات: |
BASE |
