التفاصيل البيبلوغرافية
| العنوان: |
Interhemispheric Pediatric Meningioma, YAP1 Fusion-Positive |
| المؤلفون: |
Silvia Esposito, Gianluca Marucci, Manila Antonelli, Evelina Miele, Piergiorgio Modena, Marzia Giagnacovo, Maura Massimino, Veronica Biassoni, Matilde Taddei, Marco Paolo Schiariti, Fabio Martino Doniselli, Marco Moscatelli, Luisa Chiapparini, Bianca Pollo |
| المصدر: |
Diagnostics; Volume 12; Issue 10; Pages: 2367 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
YAP1 -fusion, pediatric meningioma, interhemispheric meningioma, methylation profile |
| الوصف: |
Meningiomas are uncommon in children and usually arise in the context of tumor-predisposing syndromes. Recently, YAP1-fusions have been identified for the first time as potential NF2-independent oncogenic drivers in the development of meningiomas in pediatric patients. We report a case of a YAP1-fusion-positive atypical meningioma in a young child and compare it with the previous ones reported. Extending the clinico-pathological features of YAP1-fused meningiomas, we suggest additional clues for diagnosis and emphasize the urgent need for an integrated multilayered diagnostic approach, combining data from histological and molecular analyses, neuroradiology, and clinical findings. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Pathology and Molecular Diagnostics; https://dx.doi.org/10.3390/diagnostics12102367Test |
| DOI: |
10.3390/diagnostics12102367 |
| الإتاحة: |
https://doi.org/10.3390/diagnostics12102367Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.95C4E7A2 |
| قاعدة البيانات: |
BASE |
