التفاصيل البيبلوغرافية
| العنوان: |
Liver-Specific Contrast-Enhanced Magnetic Resonance Cholangio-Pancreatography (Ce-MRCP) in Non-Invasive Diagnosis of Iatrogenic Biliary Leakage |
| المؤلفون: |
Renato Argirò, Bruno Sensi, Leandro Siragusa, Luigi Bellini, Luigi Edoardo Conte, Camilla Riccetti, Giovanna Del Vecchio Blanco, Edoardo Troncone, Roberto Floris, Mike Salavracos, Giuseppe Tisone, Alessandro Anselmo |
| المصدر: |
Diagnostics; Volume 13; Issue 10; Pages: 1681 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2023 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
bile leak, contrast-enhanced magnetic resonance cholangio-pancreatography, percutaneous transhepatic cholangiography, hepato-biliary surgery |
| الوصف: |
Current non-invasive diagnostic modalities of iatrogenic bile leak (BL) are not particularly sensitive and often fail to localise the BL origin. Percutaneous transhepatic cholangiography (PTC) and endoscopic retrograde cholangiopancreatography (ERCP) are considered the gold standard, yet are invasive studies with potential complications. Ce-MRCP has been not comprehensively studied in this setting but may prove particularly helpful given its non-invasive nature and the anatomical dynamic detail. This paper reports a monocentric retrospective study of BL patients referred between January 2018 and November 2022 submitted to Ce-MRCP followed by PTC. The primary outcome was the accuracy of Ce-MRCP in detecting and localising BL compared to PTC and ERCP. Blood tests, coexisting cholangitis features and time for leak resolution were also investigated. Thirty-nine patients were included. Liver-specific contrast-enhanced MRCP detected BL in 69% of cases. The BL localisation was 100% accurate. Total bilirubin above 4 mg/dL was significantly associated with false negative results of Ce-MRCP. Ce-MRCP is highly accurate in detecting and localising BL, but sensitivity is significantly reduced by a high bilirubin level. Ce-MRCP may be very useful in early BL diagnosis and in accurate pre-treatment planning, but can only be reliably used in selected patients with TB < 4 mg/dL. Non-surgical techniques, both radiological and endoscopic, are proven to be effective in terms of leak resolution. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Medical Imaging and Theranostics; https://dx.doi.org/10.3390/diagnostics13101681Test |
| DOI: |
10.3390/diagnostics13101681 |
| الإتاحة: |
https://doi.org/10.3390/diagnostics13101681Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.56BC8CF2 |
| قاعدة البيانات: |
BASE |
