التفاصيل البيبلوغرافية
| العنوان: |
Antimicrobial Susceptibility of Clinical Oral Isolates of Actinomyces spp. |
| المؤلفون: |
Alexandra Wolff, Arne C. Rodloff, Paul Vielkind, Toralf Borgmann, Catalina-Suzana Stingu |
| المصدر: |
Microorganisms; Volume 10; Issue 1; Pages: 125 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Actinomyces, susceptibility testing, agar dilution, E-Test |
| جغرافية الموضوع: |
agris |
| الوصف: |
Actinomyces species play an important role in the pathogenesis of oral diseases and infections. Susceptibility testing is not always routinely performed, and one may oversee a shift in resistance patterns. The aim of the study was to analyze the antimicrobial susceptibility of 100 well-identified clinical oral isolates of Actinomyces spp. against eight selected antimicrobial agents using the agar dilution (AD) and E-Test (ET) methods. We observed no to low resistance against penicillin, ampicillin-sulbactam, meropenem, clindamycin, linezolid and tigecycline (0–2% ET, 0% AD) but high levels of resistance to moxifloxacin (93% ET, 87% AD) and daptomycin (83% ET, 95% AD). The essential agreement of the two methods was very good for benzylpenicillin (EA 95%) and meropenem (EA 92%). The ET method was reliable for correctly categorizing susceptibility, in comparison with the reference method agar dilution, except for daptomycin (categorical agreement 87%). Penicillin is still the first-choice antibiotic for therapy of diseases caused by Actinomyces spp. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Medical Microbiology; https://dx.doi.org/10.3390/microorganisms10010125Test |
| DOI: |
10.3390/microorganisms10010125 |
| الإتاحة: |
https://doi.org/10.3390/microorganisms10010125Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.E281F1F0 |
| قاعدة البيانات: |
BASE |
