دورية أكاديمية

Bax Inhibitor-1, a Conserved Cell Death Suppressor, Is a Key Molecular Switch Downstream from a Variety of Biotic and Abiotic Stress Signals in Plants

التفاصيل البيبلوغرافية
العنوان: Bax Inhibitor-1, a Conserved Cell Death Suppressor, Is a Key Molecular Switch Downstream from a Variety of Biotic and Abiotic Stress Signals in Plants
المؤلفون: Naohide Watanabe, Eric Lam
المصدر: International Journal of Molecular Sciences; Volume 10; Issue 7; Pages: 3149-3167
بيانات النشر: Molecular Diversity Preservation International
سنة النشر: 2009
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: abiotic stress, Bax Inhibitor-1, biotic stress, ER stress, programmed cell death
جغرافية الموضوع: agris
الوصف: In Nature plants are constantly challenged by a variety of environmental stresses that could lead to disruptions in cellular homeostasis. Programmed cell death (PCD) is a fundamental cellular process that is often associated with defense responses to pathogens, during development and in response to abiotic stresses in fungi, animals and plants. Although there are many characteristics shared between different types of PCD events, it remains unknown whether a common mechanism drives various types of PCD in eukaryotes. One candidate regulator for such a mechanism is Bax Inhibitor-1 (BI-1), an evolutionary conserved, endoplasmic reticulum (ER)-resident protein that represents an ancient cell death regulator that potentially regulates PCD in all eukaryotes. Recent findings strongly suggested that BI-1 plays an important role in the conserved ER stress response pathway to modulate cell death induction in response to multiple types of cell death signals. As ER stress signaling pathways has been suggested to play important roles not only in the control of ER homeostasis but also in other biological processes such as the response to pathogens and abiotic stress in plants, BI-1 might function to control the convergence point that modulates the level of the “pro-survival and pro-death” signals under multiple stress conditions.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms10073149Test
DOI: 10.3390/ijms10073149
الإتاحة: https://doi.org/10.3390/ijms10073149Test
حقوق: https://creativecommons.org/licenses/by/3.0Test/
رقم الانضمام: edsbas.F3E19497
قاعدة البيانات: BASE