دورية أكاديمية

Prevalence and Spectrum of Second Primary Malignancies among People Living with HIV in the French Dat’AIDS Cohort

التفاصيل البيبلوغرافية
العنوان: Prevalence and Spectrum of Second Primary Malignancies among People Living with HIV in the French Dat’AIDS Cohort
المؤلفون: Isabelle Poizot-Martin, Caroline Lions, Cyrille Delpierre, Alain Makinson, Clotilde Allavena, Anne Fresard, Sylvie Brégigeon, Teresa Rojas Rojas, Pierre Delobel, Group The Dat’AIDS Study Group The Dat’AIDS Study
المصدر: Cancers; Volume 14; Issue 2; Pages: 401
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2022
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: cancer survivors, HIV, AIDS, secondary primary cancer, AIDS-defining cancers, non AIDS-defining cancers
الوصف: Background: We aimed to describe the prevalence and spectrum of second primary cancer (SPC) in HIV-positive cancer survivors. Methods: A multicenter retrospective study was performed using longitudinal data from the French Dat’AIDS cohort. Subjects who had developed at least two primary cancers were selected. The spectrum of SPCs was stratified by the first primary cancer type and by sex. Results: Among the 44,642 patients in the Dat’AIDS cohort, 4855 were diagnosed with cancer between 1 December 1983 and 31 December 2015, of whom 444 (9.1%) developed at least two primary cancers. The most common SPCs in men were non-Hodgkin lymphoma (NHL) (22.8%), skin carcinoma (10%) and Kaposi sarcoma (KS) (8.4%), and in women the most common SPCs were breast cancer (16%), skin carcinoma (9.3%) and NHL (8%). The pattern of SPCs differed according to first primary cancer and by sex: in men, NHL was the most common SPC after primary KS and KS was the most common SPC after primary NHL; while in women, breast cancer was the most common SPC after primary NHL and primary breast cancer. Conclusion: The frequency and pattern of subsequent cancers among HIV-positive cancer survivors differed according to the first primary cancer type and sex.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
العلاقة: Cancer Epidemiology and Prevention; https://dx.doi.org/10.3390/cancers14020401Test
DOI: 10.3390/cancers14020401
الإتاحة: https://doi.org/10.3390/cancers14020401Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.79BFF3F0
قاعدة البيانات: BASE