دورية أكاديمية
Ultrasound-Guided Intrauterine Labeling of Rat Fetuses
| العنوان: | Ultrasound-Guided Intrauterine Labeling of Rat Fetuses |
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| المؤلفون: | Gumus, Hatice Gulcin, Illa, Miriam, Pla, Laura, Gonzalez-Neira, Anna, Demicheva, Elena, Ley, David, Crispi, Fatima, Gratacos, Eduard |
| المصدر: | Gynecologic and Obstetric Investigation; (2017) ; ISSN: 0378-7346 |
| بيانات النشر: | Karger |
| سنة النشر: | 2017 |
| المجموعة: | Lund University Publications (LUP) |
| مصطلحات موضوعية: | Other Basic Medicine, Animal model, Fetal subcutaneous tagging, Intra-amniotic injections, Pregnancy, Ultrasound-guided injections, Vital dyes |
| الوصف: | Aim: To compare intra-amniotic versus fetal subcutaneous injections for selective fetal labeling in multifetal rat pregnancies. Methods: A total of 14 pregnant rats were randomized to receive intra-amniotic injections of dyes (including Fluorescein, Indigo Carmine, or Evans Blue) or fetal subcutaneous injections (of commercial tattoo ink) both guided by ultrasound at 15-17 days of gestation. Survival, injection, and labeling success rates of both techniques were compared. Results: Survival rates (84.4% for intra-amniotic injections vs. 90.9% for fetal subcutaneous injections) and injection success rates (94% for intra-amniotic injections vs. 100% for fetal subcutaneous injections) were similar among both groups. None of the neonates from the intra-amniotic injections group were labeled at birth, while 93% of the neonates from fetal subcutaneous injections group were tagged, showing a visible spot in the skin at birth. Conclusion: Our results suggest that ultrasound-guided fetal subcutaneous injections might be an adequate strategy for selectively labeling fetuses in multifetal pregnant animals. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://lup.lub.lu.se/record/7f46d991-ddce-4c94-abec-4c3389f9d8ddTest; http://dx.doi.org/10.1159/000454766Test; pmid:28719908; scopus:85025434913 |
| DOI: | 10.1159/000454766 |
| الإتاحة: | https://doi.org/10.1159/000454766Test https://lup.lub.lu.se/record/7f46d991-ddce-4c94-abec-4c3389f9d8ddTest |
| رقم الانضمام: | edsbas.56C945B2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1159/000454766 |
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