دورية أكاديمية
Results of the first World Health Organization international collaborative study of detection of Human Papillomavirus DNA.
| العنوان: | Results of the first World Health Organization international collaborative study of detection of Human Papillomavirus DNA. |
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| المؤلفون: | Quint, W G V, Pagliusi, S, Lelie, N, de Villiers, E M, Wheeler, C M, Dillner, Joakim, Human Papillomavirus DNA international collaborative study group., World Health Organization Human Papillomavirus DNA international collaborative study group. |
| المصدر: | Journal of Clinical Microbiology; 44(2), pp 571-579 (2006) ; ISSN: 1098-660X |
| بيانات النشر: | American Society for Microbiology |
| سنة النشر: | 2006 |
| المجموعة: | Lund University Publications (LUP) |
| مصطلحات موضوعية: | Microbiology in the medical area |
| الوصف: | Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard reagent panel. The panel was designed by a group of HPV experts, and samples were prepared and distributed by the World Health Organization International Laboratory for Standards and Biologicals in The Netherlands. Each panel consisted of 24 coded samples including a dilution series for HPV types 16 and 18, alone or in combination with five other high-risk (HR) HPV types including HPV types 31, 33, 35, 45, and 52, the low-risk HPV type 6, and a negative control. Qualitative assays were generally consistent across laboratories, and most invalid results reflected a lack of HPV test sensitivity. The combined data sets had a proficiency for HPV 16 of 62.5% (15/24) and for HPV 18 of 73.9% (17/23). HPV 31 was the least accurately detected by participating laboratories. Approximately half of participating laboratories failed to detect high concentrations of HPV 31 and, to a lesser extent, to detect HPV types 35, 52, and 6. The panel sample materials offer a source of renewable and reproducible material that could be used in the future development of international standard reagents for calibration of HPV DNA assays and kits. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| ردمك: | 978-3-234-44447-5 3-234-44447-1 |
| العلاقة: | https://lup.lub.lu.se/record/1135939Test; http://dx.doi.org/10.1128/JCM.44.2.571Test–579.2006; scopus:32344444715 |
| DOI: | 10.1128/JCM.44.2.571–579.2006 |
| الإتاحة: | https://doi.org/10.1128/JCM.44.2.571Test–579.2006 https://lup.lub.lu.se/record/1135939Test |
| رقم الانضمام: | edsbas.30FA82F3 |
| قاعدة البيانات: | BASE |
| ردمك: | 9783234444475 3234444471 |
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| DOI: | 10.1128/JCM.44.2.571–579.2006 |