التفاصيل البيبلوغرافية
| العنوان: |
Lipids and polymers in pharmaceutical technology: lifelong companions |
| المؤلفون: |
Siepmann, Juergen, Faham, Amina, Clas, Sophie-Dorothee, Boyd, Ben J., Jannin, Vincent, Bernkop-Schnurch, Andreas, Zhao, Hang, Lecommandoux, Sebastien, Evans, James C., Allen, Christine, Merkel, Olivia M., Costabile, Gabriella, Alexander, Morgan R., Wildman, Ricky D., Roberts, Clive J., Leroux, Jean-Christophe |
| المساهمون: |
CHU Lille, Inserm, Université de Lille, Médicaments et Biomatériaux à libération contrôlée : Mécanismes et Optimisation - U1008 MBLC, Advanced Drug Delivery Systems (ADDS) - U1008, Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 MBLC - ADDS, DuPont Health & Nutrition, Monash Institute of Pharmaceutical Sciences Parkville MIPS, Gattefossé, Leopold Franzens Universität Innsbruck - University of Innsbruck, Laboratoire de Chimie des Polymères Organiques LCPO, University of Toronto, Ludwig Maximilian University Munich = Ludwig Maximilians Universität München LMU, University of Nottingham, UK UON, Institute of Pharmaceutical Sciences ETH Zürich IPW |
| سنة النشر: |
2024 |
| المجموعة: |
LillOA (Lille Open Archive - Université de Lille) |
| مصطلحات موضوعية: |
Gene delivery, Polymersomes, Solid dispersions, Self-emulsifying drug delivery systems, Sustained release, 3D printing, Liposomes, Peptides |
| الوصف: |
In pharmaceutical technology, lipids and polymers are considered pillar excipients for the fabrication of most dosage forms, irrespective of the administration route. They play various roles ranging from support vehicles to release rate modifiers, stabilizers, solubilizers, permeation enhancers and transfection agents. Focusing on selected applications, which were discussed at the Annual Scientific Meeting of the Gattefossé Foundation 2018, this manuscript recapitulates the fundamental roles of these two important classes of excipients, either employed alone or in combination, and provides insight on their functional properties in various types of drug formulations. Emphasis is placed on oral formulations for the administration of active pharmaceutical ingredients with low aqueous solubilities or poor permeation properties. Additionally, this review article covers the use of lipids and polymers in the design of colloidal injectable delivery systems, and as substrates in additive manufacturing technologies for the production of tailor-made dosage forms. ; 558 |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/octet-stream |
| اللغة: |
English |
| العلاقة: |
International Journal of Pharmaceutics; Int J Pharm; http://hdl.handle.net/20.500.12210/37022Test |
| الإتاحة: |
https://doi.org/20.500.12210/37022Test
https://hdl.handle.net/20.500.12210/37022Test |
| حقوق: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.B1AB1207 |
| قاعدة البيانات: |
BASE |
