التفاصيل البيبلوغرافية
العنوان: |
Usefulness of Routine Fractional Flow Reserve for Clinical Management of Coronary Artery Disease in Patients With Diabetes |
المؤلفون: |
van Belle, Eric, Cosenza, Alessandro, Baptista, Sergio Bravo, Vincent, Flavien, Henderson, John, Santos, Lino, Ramos, Ruben, Pouillot, Christophe, Calé, Rita, Cuisset, Thomas, Jorge, Elisabete, Teiger, Emmanuel, Machado, Carina, Belle, Loic, Costa, Marco, Barreau, Didier, Oliveira, Eduardo, Hanssen, Michel, Costa, João, Besnard, Cyril, Nunes, Luis, Dallongeville, Jean, Sideris, Georgios, Bretelle, Christophe, Fonseca, Nuno, Lhoest, Nicolas, Guardado, Jorge, Silva, Bruno, Sousa, Maria-João, Barnay, Pierre, Silva, João Carlos, Leborgne, Laurent, Rodrigues, Alberto, Porouchani, Sina, Seca, Luís, Fernandes, Renato, Dupouy, Patrick, Raposo, Luís |
المساهمون: |
Institut Coeur Poumon CHU Lille, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 RNMCD, Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research C2VN, Département de Cardiologie Hôpital de la Timone - APHM |
بيانات النشر: |
American Medical Association |
سنة النشر: |
2020 |
المجموعة: |
LillOA (Lille Open Archive - Université de Lille) |
مصطلحات موضوعية: |
WAVE-FREE RATIO, GUIDED PCI, REVASCULARIZATION, ANGIOGRAPHY, STRATEGY, IMPACT, RECLASSIFICATION, STENOSIS, TIME |
الوصف: |
This cross-sectional study evaluates the association of major adverse cardiac events (MACE) integrated with fractional flow reserve as the management strategy for diabetes with outcomes in patients with ambiguous lesions who undergo angiography.Key PointsQuestionWhat are the usefulness, rate of major adverse cardiovascular events (MACE), and clinical outcomes of routinely integrating fractional flow reserve in the management strategy for patients with diabetes who undergo coronary angiography? FindingsIn this cross-sectional study of 1983 patients, overall reclassification by fractional flow rate was high and similar in patients with diabetes (41.2%) and patients without diabetes (37.5%); however, reclassification from medical treatment to revascularization was more frequent among patients with diabetes. The rate of 1-year MACE was similar in reclassified (9.7%) and nonreclassified (12.0%) patients with diabetes, and the rate of MACE of patients deferred based on fractional flow reserve was similar among those with and without diabetes. MeaningThe findings suggest that management strategies guided by fractional flow reserve, including revascularization deferral, may be useful for patients with diabetes.ImportanceApproximately one-third of patients considered for coronary revascularization have diabetes, which is a major determinant of clinical outcomes, often influencing the choice of the revascularization strategy. The usefulness of fractional flow reserve (FFR) to guide treatment in this population is understudied and has been questioned. ObjectiveTo evaluate the usefulness and rate of major adverse cardiovascular events (MACE) of integrating FFR in management decisions for patients with diabetes who undergo coronary angiography. Design, Setting, and ParticipantsThis cross-sectional study used data from the PRIME-FFR study derived from the merger of the POST-IT study (Portuguese Study on the Evaluation of FFR-Guided Treatment of Coronary Disease [March 2012-November 2013]) and R3F study (French Study of FFR ... |
نوع الوثيقة: |
other/unknown material |
اللغة: |
English |
العلاقة: |
JAMA Cardiology; http://hdl.handle.net/20.500.12210/106082Test |
الإتاحة: |
https://doi.org/20.500.12210/106082Test https://hdl.handle.net/20.500.12210/106082Test |
حقوق: |
info:eu-repo/semantics/closedAccess |
رقم الانضمام: |
edsbas.A7E89E9F |
قاعدة البيانات: |
BASE |