دورية أكاديمية
Prevalence of nocturnal hypoglycemia in free-living conditions in adults with type 1 diabetes: What is the impact of daily physical activity?
| العنوان: | Prevalence of nocturnal hypoglycemia in free-living conditions in adults with type 1 diabetes: What is the impact of daily physical activity? |
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| المؤلفون: | Molveau, Joséphine, Rabasa-Lhoret, Rémi, Myette-Côté, Étienne, Messier, Virginie, Suppère, Corinne, J Potter, Kathryn, Heyman, Elsa, Tagougui, Sémah |
| المساهمون: | Université de Lille, Univ. Artois, Univ. Littoral Côte d’Opale, Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 URePSSS, Institut de Recherches Cliniques de Montréal IRCM, Montreal Heart Institute - Institut de Cardiologie de Montréal |
| سنة النشر: | 2023 |
| المجموعة: | LillOA (Lille Open Archive - Université de Lille) |
| مصطلحات موضوعية: | Adult, Blood Glucose, Blood Glucose Self-Monitoring, Diabetes Mellitus, Type 1, Exercise, Female, Glucose, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Male, Middle Aged, Prevalence, Social Conditions, Young Adult, accelerometer, continous glucose monitoring, hypoglycemia, nocturnal glucose control, physical activity level, type 1 diabetes |
| الوصف: | Studies investigating strategies to limit the risk of nocturnal hypoglycemia associated with physical activity (PA) are scarce and have been conducted in standardized, controlled conditions in people with type 1 diabetes (T1D). This study sought to investigate the effect of daily PA level on nocturnal glucose management in free-living conditions while taking into consideration reported mitigation strategies to limit the risk of nocturnal hyoglycemia in people with T1D. Data from 25 adults (10 males, 15 females, HbA: 7.6 ± 0.8%), 20-60 years old, living with T1D, were collected. One week of continuous glucose monitoring and PA (assessed using an accelerometer) were collected in free-living conditions. Nocturnal glucose values (midnight-6:00 am) following an active day "ACT" and a less active day "L-ACT" were analyzed to assess the time spent within the different glycemic target zones (10.0 mmol/L) between conditions. Self-reported data about mitigation strategies applied to reduce the risk of nocturnal hypoglycemia was also analyzed. Only 44% of participants reported applying a carbohydrate- or insulin-based strategy to limit the risk of nocturnal hypoglycemia on ACT day. Nocturnal hypoglycemia occurrences were comparable on ACT night versus on L-ACT night. Additional post-meal carbohydrate intake was higher on evenings following ACT (27.7 ± 15.6 g, ACT vs. 19.5 ± 11.0 g, L-ACT; P=0.045), but was frequently associated with an insulin bolus (70% of participants). Nocturnal hypoglycemia the night following ACT occurred mostly in people who administrated an additional insulin bolus before midnight (3 out of 5 participants with nocturnal hypoglycemia). Although people with T1D seem to be aware of the increased risk of nocturnal hypoglycemia associated with PA, the risk associated with additional insulin boluses may not be as clear. Most participants did not report using compensation strategies to reduce the risk of PA related late-onset hypoglycemia which may be because they did not consider habitual PA as something ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/octet-stream; application/rdf+xml; charset=utf-8 |
| اللغة: | English |
| العلاقة: | Frontiers in Endocrinology; Front Endocrinol (Lausanne); http://hdl.handle.net/20.500.12210/79296Test |
| الإتاحة: | https://doi.org/20.500.12210/79296Test https://hdl.handle.net/20.500.12210/79296Test |
| حقوق: | Attribution 3.0 United States ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.43E90A48 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |