رسالة جامعية
Air travel and venous thrombosis : results of the WRIGHT study : Part I: Epidemiology
| العنوان: | Air travel and venous thrombosis : results of the WRIGHT study : Part I: Epidemiology |
|---|---|
| المؤلفون: | Kuipers, S. |
| المساهمون: | Rosendaal, F.R., Büller, H.B., Leiden University |
| سنة النشر: | 2009 |
| المجموعة: | Leiden Repository (Leiden University) |
| مصطلحات موضوعية: | Air travel, Immobilisation, Long distance travel, Pulmonary embolism, Thrombophilia, Venous thrombosis |
| الوصف: | In venous thrombosis, a blood clot develops in a vein, usually a deep vein of the leg, causing obstruction of the blood flow. Venous thrombosis is a multicausal disease, in which genes and environment interact. One of the environmental factors that increases the risk of venous thrombosis is long distance travel. This thesis describes the results of several studies on epidemiological aspects of the association between long distance travel and venous thrombosis. In a study among frequently traveling employees of international organizations, the absolute risk of venous thrombosis after long distance flights, the effect of duration of travel, time after travel and exposure to several flights at the same time and the effect of interaction with other risk factors for venous thrombosis was assessed. In a population-based case-control study, the effect of elevated levels of coagulation factors in long distance travelers was evaluated. Finally, the occurrence of venous thrombosis among commercial airline pilots was studied. The main conclusion is that the risk of venous thrombosis in healthy travellers is not high enough to promote widespread use of aggressive prophylaxis, such as anticoagulant therapy. However, in some travellers at increased risk, the risk-benefit ratio may favour the use of prophylactic measures. ; UBL - phd migration 2018 |
| نوع الوثيقة: | doctoral or postdoctoral thesis |
| وصف الملف: | application/pdf |
| اللغة: | English |
| ردمك: | 978-94-90122-49-2 94-90122-49-1 |
| العلاقة: | lucris-id: 24722087; https://hdl.handle.net/1887/14014Test |
| الإتاحة: | https://hdl.handle.net/1887/14014Test |
| رقم الانضمام: | edsbas.86BEA355 |
| قاعدة البيانات: | BASE |
| ردمك: | 9789490122492 9490122491 |
|---|