دورية أكاديمية
Molecular epidemiology and evolutionary trajectory of emerging echovirus 30, Europe
| العنوان: | Molecular epidemiology and evolutionary trajectory of emerging echovirus 30, Europe |
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| المؤلفون: | Benschop, K.S.M., Broberg, E.K., Hodcroft, E., Schmitz, D., Albert, J., Baicus, A., Bailly, J.L., Baldvinsdottir, G., Berginc, N., Blomqvist, S., Bottcher, S., Brytting, M., Bujaki, E., Cabrerizo, M., Celma, C., Cinek, O., Claas, E.C.J., Cremer, J., Dean, J., Dembinski, J.L., Demchyshyna, I., Diedrich, S., Dudman, S., Dunning, J., Dyrdak, R., Emmanouil, M., Farkas, A., Gascun, C. de, Fournier, G., Georgieva, I., Gonzalez-Sanz, R., Hooydonk-Elving, J. van, Jaaskelainen, A.J., Jancauskaite, R., Keeren, K., Fischer, T.K., Krokstad, S., Nikolaeva-Glomb, L., Novakova, L., Midgley, S.E., Mirand, A., Molenkamp, R., Morley, U., Mossong, J., Muralyte, S., Murk, J.L., Nguyen, T., Nordbo, S.A., Osterback, R., Pas, S., Pellegrinelli, L., Pogka, V., Prochazka, B., Rainetova, P., Ranst, M. van, Roorda, L., Schuffenecker, I., Schuurman, R., Stoyanova, A., Templeton, K., Verweij, J.J., Voulgari-Kokota, A., Vuorinen, T., Wollants, E., Wolthers, K.C., Zakikhany, K., Neher, R., Harvala, H., Simmonds, P. |
| المصدر: | Emerging Infectious Diseases |
| سنة النشر: | 2021 |
| المجموعة: | Leiden Repository (Leiden University) |
| الوصف: | In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016-2018. Most E30 cases affected persons 0-4 years of age (29%) and 25-34 years of age (27%). Sequences were divided into 6 genetic clades (G1-G6). Most (53%) sequences belonged to G1, followed by G6 (23%), G2 (17%), G4 (4%), G3 (0.3%), and G5 (0.2%). Each clade encompassed unique individual recombinant forms; G1 and G4 displayed >= 2 unique recombinant forms. Rapid turnover of new clades and recombinant forms occurred over time. Clades G1 and G6 dominated in 2018, suggesting the E30 upsurge was caused by emergence of 2 distinct clades circulating in Europe. Investigation into the mechanisms behind the rapid turnover of E30 is crucial for clarifying the epidemiology and evolution of these enterovirus infections. ; Molecular basis of virus replication, viral pathogenesis and antiviral strategies |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://wwwnc.cdc.gov/eid/article/27/6/pdfs/20-3096.pdfTest; lumc-id: 122175953; https://hdl.handle.net/1887/3249094Test |
| DOI: | 10.3201/eid2706.203096 |
| الإتاحة: | https://doi.org/10.3201/eid2706.203096Test https://hdl.handle.net/1887/3249094Test https://wwwnc.cdc.gov/eid/article/27/6/pdfs/20-3096.pdfTest |
| رقم الانضمام: | edsbas.C810A878 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3201/eid2706.203096 |
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