دورية أكاديمية
Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis
| العنوان: | Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis |
|---|---|
| المؤلفون: | Houen, Gunnar, Heiden, Julie, Trier, Nicole H, Draborg, Anette H, Benros, Michael E, Zinkevičiūtė, Rūta, Petraitytė-Burneikienė, Rasa, Čiplys, Evaldas, Slibinskas, Rimantas, Frederiksen, Jette L |
| المصدر: | Journal of neuroimmunology, Amsterdam : Elsevier, 2020, vol. 346, art. no. 577314, p. [1-17] ; ISSN 0165-5728 ; eISSN 1872-8421 |
| سنة النشر: | 2020 |
| المجموعة: | LAEI VL (Lithuanian Institute of Agrarian Economics Virtual Library) / LAEI VB (Lietuvos agrarinės ekonomikos institutasvirtualią biblioteką) |
| مصطلحات موضوعية: | Epstein Barr virus, Multiple sclerosis, Neurotrophic virus, Optic neuritis, Virus antigens |
| الوصف: | Antibody indices to Measles, Mumps, Varicella Zoster (MRZ) are of diagnostic value in multiple sclerosis (MS). Here, we have investigated, if this panel could be extended to increase diagnostic value. Samples from relapsing-remitting (RR) MS and optic neuritis (ON) patients were tested for reactivity to antigens from Epstein-Barr, Varicella Zoster, Measles, Mumps and Rubella (EMMRZ) viruses. Increased IgG levels in serum and cerebrospinal fluid (CSF) were found in RRMS patients, along with a significant correlation between serum and CSF. The sensitivity of the EMMRZ panel was increased approximately 40% compared to the MRZ panel, suggesting that the EMMRZ panel may be useful in MS and ON diagnostics. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | http://vu.lvb.lt/VU:ELABAPDB65772421&prefLang=en_USTest |
| الإتاحة: | https://doi.org/10.1016/j.jneuroim.2020.577314Test http://vu.lvb.lt/VU:ELABAPDB65772421&prefLang=en_USTest |
| رقم الانضمام: | edsbas.841067AE |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |