دورية أكاديمية
Mode of Death Among Japanese Adults With Heart Failure With Preserved, Midrange, and Reduced Ejection Fractio
| العنوان: | Mode of Death Among Japanese Adults With Heart Failure With Preserved, Midrange, and Reduced Ejection Fractio |
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| المؤلفون: | Kitai, Takeshi, Miyakoshi, Chisato, Morimoto, Takeshi, Yaku, Hidenori, Murai, Ryosuke, Kaji, Shuichiro, Furukawa, Yutaka, Inuzuka, Yasutaka, Nagao, Kazuya, Tamaki, Yodo, Yamamoto, Erika, Ozasa, Neiko, Tang, W. H. Wilson, Kato, Takao, Kimura, Takeshi |
| المساهمون: | 加藤, 貴雄, 木村, 剛, 30583877 |
| بيانات النشر: | American Medical Association (AMA) |
| سنة النشر: | 2020 |
| المجموعة: | Kyoto University Research Information Repository (KURENAI) / 京都大学学術情報リポジトリ |
| الوصف: | [Importance] Despite intensive treatment, hospitalized patients with acute decompensated heart failure (ADHF) have a substantial risk of postdischarge mortality. Limited data are available on the possible differences in the incidence and mechanisms of death among patients with heart failure with reduced ejection fraction (HFrEF), heart failure with midrange ejection fraction (HFmrEF), and heart failure with preserved ejection fraction (HFpEF). [Objectives] To examine the incidences and mode of postdischarge mortality among patients with ADHF and to compare the risk profile among patients with HFrEF, HFmrEF, and HFpEF. [Design, Setting, and Participants] This prospective cohort study of 4056 patients hospitalized for ADHF analyzed data from 3717 patients who were discharged from October 1, 2014, to March 31, 2016. Data analysis was performed from April 1 to August 31, 2019. [Exposures] Death among patients with ADHF after hospital discharge. [Main Outcomes and Measures] All-cause death and cause of postdischarge mortality after the index hospitalization by left ventricular ejection fraction (LVEF) subgroup. [Results] A total of 3717 patients (mean [SD] age, 77.7 [12.0] years; 2049 [55.1%] male) were included in the study. The mean (SD) LVEF at baseline was 46.4% (16.2%). Among 3717 enrolled patients, 1383 (37.2%) were categorized as having HFrEF (LVEF, <40%), 703 (18.9%) as having HFmrEF (LVEF, 40%-49%), and 1631 (43.9%) as having HFpEF (LVEF, ≥50%). The incidence and causes of death were evaluated after discharge from the index hospitalization. The median follow-up period was 470 days (interquartile range, 357-649 days), and the 1-year follow-up rate was 96%. During follow-up, all-cause death occurred in 848 patients (22.8%; HFrEF group: 298 [21.5%; 95% CI, 19.5%-23.8%]; HFmrEF group: 158 [22.5%; 95% CI, 19.5%-25.7%]; and HRpEF group: 392 [24.0%; 95% CI, 22.0%-26.2%]; P = .26), cardiovascular deaths occurred in 523 patients (14.1%; HFrEF group: 203 [14.7%; 95% CI, 12.9%-16.6%]; HFmrEF group: 97 [13.8%; 95% ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2574-3805 32379331 |
| العلاقة: | http://hdl.handle.net/2433/250820Test; JAMA Network Open; e204296 |
| الإتاحة: | http://hdl.handle.net/2433/250820Test |
| حقوق: | This is an open access article distributed under the terms of the CC-BY License. © 2020 Kitai T et al. |
| رقم الانضمام: | edsbas.72CD93FF |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 25743805 32379331 |
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