المؤلفون: Astarcioglu M.A., Kilit C., Sen T., Durmus H.I., Kalcik M., Gursoy M.O., Yesin M.

مصطلحات موضوعية: Chronic total occlusion, Percutaneous transluminal angioplasty, Peripheral arterial disease

الوصف: Objective This study aimed to evaluate the safety and the efficacy of primary stenting to treat Trans-Atlantic Inter-Society Consensus II (TASC) D femoropopliteal lesions. Background Advances in wire, balloon and stent design have been reported to improve the durability of stenting of longer femoropopliteal lesions. Methods A total of 57 limbs of 53 patients with Rutherford stage 3 to 6 due to TASC D femoropopliteal lesions were treated with a self-expanding nitinol stent in a prospective, single-centre, observational study. End points of interest included primary and secondary patency, target lesion revascularization, in-stent restenosis, major adverse cardiovascular events, Rutherford class improvement and change in walking capacity at 1 year. Results A total of 53 patients (57 lesions) were treated with a self-expanding nitinol stent and final procedural success was 91.2%. The median length of the treated segment was 330 ± 96 mm. The median stented segment was 366 ± 71 mm and the mean number of the stents was 2.1 ± 0.9. At 1 year, primary and secondary patency rates were 63.9% and 82.1%, respectively. Major adverse cardiovascular events occurred in 11 patients (22.9%), and significant benefits were observed in Rutherford class and walking distance (both P < 0.001). Conclusions Primary implantation of self-expanding nitinol stents for the treatment of TASC D femoropopliteal lesions appears to be safe and effective, especially in patients who have multiple co-morbidities and a high risk for surgical bypass. The risk of restenosis was higher when long stenting was extended to the popliteal artery. © 2017 Belgian Society of Cardiology.

العلاقة: Acta Cardiologica; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://dx.doi.org/10.1080/00015385.2017.1281521Test; https://hdl.handle.net/20.500.12438/7227Test; 72; 36; 40

الإتاحة: https://doi.org/20.500.12438/7227Test
https://doi.org/10.1080/00015385.2017.1281521Test
https://hdl.handle.net/20.500.12438/7227Test

المؤلفون: Astarcio?lu M.A., Şen T., Durmuş H.I., Amasyali B.

مصطلحات موضوعية: Angioplasty, Arterial occlusive diseases, Ballon, Ischemia/therapy, Popliteal artery/radiography

الوصف: The increasing prevalence of critical lower limb ischemia is frequently associated with complex tibioperoneal obstructive disease and a high rate of amputation. In this article, we report our recent experience in order to highlight this valuable and underutilised technique, which proved successful in a complicated case where a conventional approach failed. © 2015 Turkish Society of Cardiology.

العلاقة: Turk Kardiyoloji Dernegi Arsivi; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://dx.doi.org/10.5543/tkda.2015.45380Test; https://hdl.handle.net/20.500.12438/7794Test; 43; 478; 480

الإتاحة: https://doi.org/20.500.12438/7794Test
https://doi.org/10.5543/tkda.2015.45380Test
https://hdl.handle.net/20.500.12438/7794Test

المؤلفون: Uyarel H., Erdem I., Dayi Ş.Ü., Kaşikçioglu H., Tartan Z., Akgül Ö., Šimşek D.

مصطلحات موضوعية: Angioplasty, transluminal, percutaneous coronary, Coronary circulation/drug effects, Myocardial infarction/drug therapy, Myocardial reperfusion/methods, Platelet aggregation inhibitors, Platelet glycoprotein GPIIb-IIIa complex

الوصف: Objectives: We evaluated the effect of glycoprotein (GP) IIb/IIIa receptor inhibition on ST-segment resolution in patients undergoing primary percutaneous coronary intervention (PCI) for acute myocardial infarction (MI). Study design: We retrospectively analyzed 115 patients (96 males, 19 females; mean age 57.7 years; range 39 to 82 years) who presented with ST-segment elevation acute MI and treated within 12 hours with successful primary PCI (TIMI III flow). Of these, a GP IIb/IIIa receptor blocker (tirofiban) was used in 64 patients. The arithmetic sum of ST-segments was obtained in millimeters on electrocardiograms immediately before angioplasty and after 60 minutes of TIMI III flow restoration. The difference between the two measurements was accepted as resolution of the sum of ST-segment elevation and expressed as ?STR. Results: There were no significant differences between the two treatment groups regarding age, gender, cardiovascular risk factors, laboratory parameters, duration from angina onset to emergency service and from door to angioplasty. Patients who received tirofiban had a greater ASTR than those who did not (7.2±2.8 mm vs 4.2±2.6 mm, respectively; p<0.001). A significant and positive correlation was seen between GP IIb/IIIa inhibition and ?STR (r=0.336, p<0.001). In a multivariate linear regression model including nine variables, GP IIb/IIIa inhibition was found as the only independent determinant of ASTR (p<0.001). Conclusion: Glycoprotein IIb/IIIa inhibition helps preserve microvascular perfusion in patients with TIMI III flow after primary PCI.

العلاقة: Turk Kardiyoloji Dernegi Arsivi; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/20.500.12438/6308Test; 33; 204; 211

الإتاحة: https://doi.org/20.500.12438/6308Test
https://hdl.handle.net/20.500.12438/6308Test