دورية أكاديمية
The frequency, risk factors, and complications of gastrointestinal dysfunction during enteral nutrition in critically ill patients
| العنوان: | The frequency, risk factors, and complications of gastrointestinal dysfunction during enteral nutrition in critically ill patients |
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| المساهمون: | Şentürk, Evren, Atasever, Ayşe Gülşah, Özcan, Perihan Ergin, Kasalı, Kamber, Abdullah, Taner, Orhun, Günseli, School of Medicine, Department of Anaesthesiology and Intensive Care |
| المصدر: | Therapeutics and Clinical Risk Management |
| بيانات النشر: | Dove Medical Press International |
| سنة النشر: | 2018 |
| المجموعة: | Koç University Suna Kıraç Library’ Digital Collections |
| مصطلحات موضوعية: | Medicine, Health care sciences and services, Intensive care units, Enteral nutrition, Water-electrolyte balance, Drug resistance, Multiple, Bacterial, Gastrointestinal motility, Length of stay |
| الوصف: | Background: Gastrointestinal (GI) motility disorders in intensive care patients remain relatively unexplored. Nowadays, the frequency, risk factors and complications of GI dysfunction during enteral nutrition (EN) become more questionable. Aim: To evaluate the frequency, risk factors and complications of GI dysfunction during EN in the first 2 weeks of the intensive care unit (ICU) stay and to identify precautions to prevent the development of GI dysfunction and avoid complications. Methods: In this prospective observational study, we deliberately targeted at-risk patients. A total of 137 patients who received nasogastric tube feeding in an ICU of a tertiary hospital were enrolled. Results: The incidence of GI dysfunction that was found to be 63% which was associated mainly between MDR bacteria positivity and negative fluid balance. Diarrhea was observed in 36 patients (26%) and on 147 patient-days (incidence rate, 5.5 per 100 patient-days). The median day of diarrhea onset was 6 days after the initiation of EN. Forty patients (29%) presented with constipation (85% during the first week). Fifty patients (36%) exhibited upper digestive intolerance on 212 patient-days (incidence rate, 7.9 per 100 patient-days), after a median EN duration of 6 days (range, 2-14 days). Logistic regression analysis revealed MDR bacteria growth in the culture (OR, 1.75; 95% CI, 1.15-2.67; P=0.008) and negative fluid balance (OR, 0.57; 95% CI, 0.34-0.94; P=0.03) as the risk factors for GI dysfunction. We also showed that GI dysfunction was associated with high SOFA score, hypo-albuminemia, catecholamine use, and prolonged length of stay (LOS). GI dysfunction, on the other hand, can cause some complications including inadequate nutrition, and newly developed decubitus ulcers. Conclusion: GI dysfunction should be considered a clinical predictor of inadequate nutrition and prolonged LOS. In addition, the most dramatic risk for GI dysfunction was observed in patients with MDR bacteria growth in the culture and patients in negative fluid ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | |
| اللغة: | English |
| تدمد: | 1176-6336 1178-203X |
| العلاقة: | Publisher version; Koç University Institutional Repository; 48359; Atasever, Ayse G., Perihan E. Özcan, Kamber Kasali, Taner Abdullah, Gunseli Orhun, and Evren Senturk. "The Frequency, Risk Factors, and Complications of Gastrointestinal Dysfunction During Enteral Nutrition in Critically Ill Patients." Therapeutics and Clinical Risk Management. 14 (2018): 385-391.; https://dx.doi.org/10.2147/TCRM.S158492Test; IR01499.pdf; KOCUN\SENEMACAR; WoS; Scopus; PubMed; NA; http://libdigitalcollections.ku.edu.tr/cdm/ref/collection/IR/id/8063Test |
| DOI: | 10.2147/TCRM.S158492 |
| الإتاحة: | https://doi.org/10.2147/TCRM.S158492Test http://libdigitalcollections.ku.edu.tr/cdm/ref/collection/IR/id/8063Test |
| رقم الانضمام: | edsbas.ECB776A9 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 11766336 1178203X |
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| DOI: | 10.2147/TCRM.S158492 |