التفاصيل البيبلوغرافية
| العنوان: |
Tetramethylrhodamine is an essential scaffold of azide probe in detecting cellular acrolein |
| المؤلفون: |
Pradipta A., Fujii M., Tanei T., Morimoto K., Shimazu K., Noguchi S., Tanaka K. |
| المصدر: |
SCOPUS09680896-2019-27-11-SID85064499606 |
| سنة النشر: |
2019 |
| المجموعة: |
Kazan Federal University Digital Repository |
| مصطلحات موضوعية: |
1,3-Dipolar cycloaddition, Acrolein, Breast cancer cell lines, Phenyl azide, TAMRA |
| الوصف: |
© 2019 Elsevier Ltd Tetramethylrhodamine (TAMRA)-phenyl azide is a chemical probe used to detect intracellular acrolein directly in live cells. Herein, we demonstrated that TAMRA is the optimum fluorophore for the probe. TAMRA-phenyl azide was used to reveal that high levels of acrolein are generated in a variety of breast cancer cells, regardless of the tumor subtype. These findings corroborate the analysis presented in our previous report, in which TAMRA-phenyl azide was used to label breast cancer tissues resected from breast cancer patients. Because high levels of acrolein were generated in all cancer cell types, we believe that acrolein detection may be useful as a general method for labeling cancerous tissues. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| تدمد: |
0968-0896 |
| العلاقة: |
Bioorganic and Medicinal Chemistry; 11; 27; 2228; http://dspace.kpfu.ru/xmlui/bitstream/net/157601/-1/SCOPUS09680896-2019-27-11-SID85064499606-p1.pdfTest; https://dspace.kpfu.ru/xmlui/handle/net/157601Test |
| الإتاحة: |
https://dspace.kpfu.ru/xmlui/handle/net/157601Test |
| رقم الانضمام: |
edsbas.151C9145 |
| قاعدة البيانات: |
BASE |
