كتاب
Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs
| العنوان: | Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs |
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| المؤلفون: | Mieda Michihiro, Sakurai Takeshi |
| بيانات النشر: | Springer Science+Business Media |
| سنة النشر: | 2015 |
| المجموعة: | Kanazawa University Repository for Academic Resources (KURA) / 金沢大学学術情報リポジトリ |
| مصطلحات موضوعية: | Hypothalamus, Narcolepsy, Neuropeptide, Orexin, Preoptic area, Sleep-wakefulness, Transgenic mice |
| الوصف: | Sleep and wakefulness are controlled by a complex network of neurons harboring diverse neurochemical characteristics, including glutamatergic, GABAergic, monoaminergic, cholinergic, and peptidergic neurons. To understand the precise role of each type of neuron in this circuit, it is useful to artificially manipulate the activity of a particular type of neuron to see its effect on behavior. The DREADD system has made such a strategy possible. Here, we review our recent work using DREADD to pharmacogenetically dissect neural mechanisms regulating sleep-wakefulness, describe the protocol we used, and discuss the technical aspects of our studies. © Springer Science+Business Media New York 2015. All rights reserved. ; Book Chapter, Embargo Period 12 months |
| نوع الوثيقة: | book |
| اللغة: | English |
| ردمك: | 978-1-4939-2944-3 978-1-4939-2943-6 1-4939-2944-5 1-4939-2943-7 |
| العلاقة: | https://kanazawa-u.repo.nii.ac.jp/?action=repository_uri&item_id=14191Test; http://hdl.handle.net/2297/44892Test; Designer Receptors Exclusively Activated by Designer Drugs, 108(the series Neuromethods), 109-127(2015-09-04); https://kanazawa-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=14191&item_no=1&attribute_id=26&file_no=1Test |
| الإتاحة: | http://hdl.handle.net/2297/44892Test https://kanazawa-u.repo.nii.ac.jp/?action=repository_uri&item_id=14191Test https://kanazawa-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=14191&item_no=1&attribute_id=26&file_no=1Test |
| رقم الانضمام: | edsbas.5F0E9236 |
| قاعدة البيانات: | BASE |
| ردمك: | 9781493929443 9781493929436 1493929445 1493929437 |
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