مراجعة
Single-fraction gamma-knife radiosurgery with or without previous surgery for cavernous sinus meningiomas: A single-center experience and systematic literature review
| العنوان: | Single-fraction gamma-knife radiosurgery with or without previous surgery for cavernous sinus meningiomas: A single-center experience and systematic literature review |
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| المؤلفون: | Başak, Ahmet T., Özbek, Muhammet Arif |
| بيانات النشر: | NLM (Medline) |
| سنة النشر: | 2023 |
| المجموعة: | İstanbul Medipol University Institutional Repository (DSpace@Medipol) |
| مصطلحات موضوعية: | Cavernous Sinus, Gamma-Knife, Meningioma |
| الوصف: | Background: The most effective treatment method for meningiomas is surgical treatment. However, complete resection of cavernous sinus meningiomas is quite difficult. The biggest reasons for this are; narrow surgical corridor, the optic chiasm is the close relationship between the cranial nerves and anterior cerebral and internal carotid arteries. Gamma knife radiosurgery (GKRS) may be a good option in these lesions with high mortality and morbidity. Aim: This study aimed to evaluate and compare the early effects at a mean of 6 months and 3 years and outcomes between surgery followed by gamma knife radiosurgery (GKRS) and GKRS alone for cavernous sinus meningiomas. Methods: We included 20 patients with cavernous sinus meningioma treated via single fraction Leksell Gamma Knife Perfexion (Elekta Instruments; Stockholm, Sweden) between 2015 and 2018. The mean age of the patients was 54.95 (range: 32-77) years. Nine patients underwent primary surgery (for the resection of extracavernous components of the tumor) followed by GKRS (for the resection of intracavernous components of the tumor) (group A). Meanwhile, 11 patients were managed with GKRS alone (group B). The tumor volume ranged from 2.8 to 32.8 (mean: 14.76) cm3 and the isodose to the tumor margin from 10 to 13.5 (mean: 11.65) Gy. Results: In total, 20 patients were followed up at a mean time of 18.95 (range: 6-36) months. The mean Karnofsky Performance Score of the patients was 95.2%. The mean follow up times of groups A and B were 23.6 and 15 months, respectively. Meanwhile, only patients with a follow up time of at least 6 months were included in the study. The mean follow up time after GKRS in group A was 17.6 months. There was no change in the tumor volume in 15% of patients. In the remaining cases, the tumor volume decreased. The mean tumor regression rates were 82.2% in Group A and 17.7% in Group B. The tumor volume did not decrease in three patients (n = 1, group A and n = 2, group B). Cranial nerve deficits improved, worsened, and remained stable in ... |
| نوع الوثيقة: | review |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1119-3077 2229-7731 37357468 |
| العلاقة: | Nigerian Journal of Clinical Practice; Diğer; Başak, A. T. ve Özbek, M. A. (2023). Single-fraction gamma-knife radiosurgery with or without previous surgery for cavernous sinus meningiomas: A single-center experience and systematic literature review. Nigerian Journal of Clinical Practice, 26(5), 545-551. https://dx.doi.org/10.4103/njcp.njcp_2033_21Test; https://dx.doi.org/10.4103/njcp.njcp_2033_21Test; https://hdl.handle.net/20.500.12511/11183Test; 26; 545; 551; Q4; 001049292600003; 2-s2.0-85162839896; Q3 |
| DOI: | 10.4103/njcp.njcp_2033_21 |
| الإتاحة: | https://doi.org/20.500.12511/11183Test https://doi.org/10.4103/njcp.njcp_2033_21Test https://hdl.handle.net/20.500.12511/11183Test |
| حقوق: | info:eu-repo/semantics/openAccess ; Attribution-NonCommercial-ShareAlike 4.0 International ; https://creativecommons.org/licenses/by-nc-sa/4.0Test/ |
| رقم الانضمام: | edsbas.27C235AD |
| قاعدة البيانات: | BASE |
| تدمد: | 11193077 22297731 37357468 |
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| DOI: | 10.4103/njcp.njcp_2033_21 |