دورية أكاديمية
The three facets of the SARS-CoV-2 pandemic during the first two waves in the northern, central, and southern Italy
| العنوان: | The three facets of the SARS-CoV-2 pandemic during the first two waves in the northern, central, and southern Italy |
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| المؤلفون: | Buscemi, Silvio, Davoli, Chiara, Trecarichi, Enrico Maria, Morrone, Helen Linda, Tassone, Bruno, Buscemi, Carola, Randazzo, Cristiana, Barile, Anna Maria, Colombrita, Piero, Soresi, Maurizio, Giannitrapani, Lydia, Cascio, Antonio, Scichilone, Nicola, Cottone, Carlo, Sbraccia, Paolo, Guglielmi, Valeria, Leonetti, Frida, Malavazos, Alexis Elias, Basilico, Sara, Carruba, Michele, Santini, Ferruccio, Antonelli, Alessandro, Viola, Nicola, Romano, Marcello, Cesana, Bruno Mario, Torti, Carlo |
| المساهمون: | Buscemi, Silvio, Davoli, Chiara, Trecarichi, Enrico Maria, Morrone, Helen Linda, Tassone, Bruno, Buscemi, Carola, Randazzo, Cristiana, Barile, Anna Maria, Colombrita, Piero, Soresi, Maurizio, Giannitrapani, Lydia, Cascio, Antonio, Scichilone, Nicola, Cottone, Carlo, Sbraccia, Paolo, Guglielmi, Valeria, Leonetti, Frida, Malavazos, Alexis Elia, Basilico, Sara, Carruba, Michele, Santini, Ferruccio, Antonelli, Alessandro, Viola, Nicola, Romano, Marcello, Cesana, Bruno Mario, Torti, Carlo |
| بيانات النشر: | ELSEVIER NL |
| سنة النشر: | 2023 |
| المجموعة: | IRIS Università degli Studi di Palermo |
| مصطلحات موضوعية: | COVID-19, Epidemiology, Italy, Mortality, Public health, SARS-CoV-2, Settore MED/49 - Scienze Tecniche Dietetiche Applicate, Settore MED/09 - Medicina Interna, Settore MED/13 - Endocrinologia |
| الوصف: | Background: There is a scarcity of information in literature regarding the clinical differences and comorbidities of patients affected by Coronavirus disease 2019 (COVID-19), which could clarify the different prevalence of the outcomes (composite and only death) between several Italian regions. Objective: This study aimed to assess the heterogeneity of clinical features of patients with COVID-19 upon hospital admission and disease outcomes in the northern, central, and southern Italian regions. Methods: An observational cohort multicenter retrospective study including 1210 patients who were admitted for COVID-19 in Infectious diseases, Pulmonology, Endocrinology, Geriatrics and Internal Medicine Units in Italian cities stratified between north (263 patients); center (320 patients); and south (627 patients), during the first and second pandemic waves of SARS-CoV-2 (from February 1, 2020 to January 31, 2021). The data, obtained from clinical charts and collected in a single database, comprehended demographic characteristics, comorbidities, hospital and home pharmacological therapies, oxygen therapy, laboratory values, discharge, death and Intensive care Unit (ICU) transfer. Death or ICU transfer were defined as composite outcomes. Results: Male patients were more frequent in the northern Italian region than in the central and southern regions. Diabetes mellitus, arterial hypertension, chronic pulmonary and chronic kidney diseases were the comorbidities more frequent in the southern region; cancer, heart failure, stroke and atrial fibrillation were more frequent in the central region. The prevalence of the composite outcome was recorded more frequently in the southern region. Multivariable analysis showed a direct association between the combined event and age, ischemic cardiac disease, and chronic kidney disease, in addition to the geographical area. Conclusions: Statistically significant heterogeneity was observed in patients with COVID-19 characteristics at admission and outcomes from northern to southern Italy. ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36801631; info:eu-repo/semantics/altIdentifier/wos/WOS:000944613600001; volume:16; issue:4; firstpage:520; lastpage:525; numberofpages:6; journal:JOURNAL OF INFECTION AND PUBLIC HEALTH; https://hdl.handle.net/10447/582671Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85148662259 |
| DOI: | 10.1016/j.jiph.2023.02.002 |
| الإتاحة: | https://doi.org/10.1016/j.jiph.2023.02.002Test https://hdl.handle.net/10447/582671Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2A2702D0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jiph.2023.02.002 |
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