دورية أكاديمية
Migraine, Cognitive Decline, and Dementia in Older Adults: A Population-Based Study
| العنوان: | Migraine, Cognitive Decline, and Dementia in Older Adults: A Population-Based Study |
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| المؤلفون: | Liang, Yajun, Gao, Ya, Wang, Rui, Grande, Giulia, Monastero, Roberto, Dong, Yanhong, Jiang, Xin, Lv, Peiyuan, Qiu, Chengxuan |
| المساهمون: | Liang, Yajun, Gao, Ya, Wang, Rui, Grande, Giulia, Monastero, Roberto, Dong, Yanhong, Jiang, Xin, Lv, Peiyuan, Qiu, Chengxuan |
| بيانات النشر: | IOS PRESS NL |
| سنة النشر: | 2022 |
| المجموعة: | IRIS Università degli Studi di Palermo |
| مصطلحات موضوعية: | Cognitive aging, dementia, headache, migraine, population-based study, Settore MED/26 - Neurologia |
| الوصف: | Background: The potential impact of migraine on cognitive aging among older adults remains controversial.Objective: To examine the relationship of migraine and subtypes with cognitive decline and dementia in an older Swedish population.Methods: This population-based study included 3,069 participants (age >= 60 years) from the Swedish National study on Aging and Care in Kungsholmen, Stockholm. Baseline examination was conducted in 2001-2004, and participants were followed every 3 or 6 years until 2013-2016. Data were collected through face-to-face interviews, clinical examinations, laboratory tests, and linkage with registers. Global cognitive function was measured with the Mini-Mental State Examination (MMSE). Dementia was diagnosed according to the DSM-IV criteria. Migraine and subtypes were defined following the international classification system. Data were analyzed using logistic regression, Cox regression, and linear mixed-effects models.Results: At baseline, 305 participants were defined with non-migraine headache and 352 with migraine. The crosssectional analysis showed that the multivariable-adjusted odds ratio (95% confidence interval) of prevalent dementia was 0.49 (0.20-1.21) for migraine and 0.66 (0.26-1.66) for migraine without aura. The longitudinal analysis showed that the multivariable-adjusted hazard ratios of incident dementia associated with migraine and subtypes ranged 0.68-0.89 (p > 0.05). Furthermore, migraine and subtypes were not significantly associated with either baselineMMSEscore orMMSEchanges during follow-ups (p > 0.05). The nonsignificant associations did not vary substantially by age, APOE epsilon 4 allele, cerebrovascular disease, and antimigraine treatment (p for interactions > 0.05).Conclusion: This study shows no evidence supporting the associations of migraine and its subtypes with cognitive decline and dementia among older adults. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35570487; info:eu-repo/semantics/altIdentifier/wos/WOS:000828029000021; volume:88; issue:1; firstpage:263; lastpage:271; numberofpages:9; journal:JOURNAL OF ALZHEIMER'S DISEASE; https://hdl.handle.net/10447/585434Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85133727131 |
| DOI: | 10.3233/JAD-220013 |
| الإتاحة: | https://doi.org/10.3233/JAD-220013Test https://hdl.handle.net/10447/585434Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.A072DF8C |
| قاعدة البيانات: | BASE |
| DOI: | 10.3233/JAD-220013 |
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