دورية أكاديمية
Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled Analysis of Case‐Control Studies of the Stop Consortium
| العنوان: | Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled Analysis of Case‐Control Studies of the Stop Consortium |
|---|---|
| المؤلفون: | Collatuzzo G., Teglia F., Pelucchi C., Negri E., Rabkin C. S., Liao L. M., Sinha R., Lopez-carrillo L., Lunet N., Morais S., Aragones N., Moreno V., Vioque J., de la Hera M. G., Ward M. H., Malekzadeh R., Pakseresht M., Hernandez-ramirez R. U., Lopez-cervantes M., Bonzi R., Dalmartello M., Tsugane S., Hidaka A., Camargo M. C., Curado M. P., Zhang Z. -F., Zubair N., Vecchia C. L., Shah S., Boffetta P. |
| المساهمون: | Collatuzzo G., Teglia F., Pelucchi C., Negri E., Rabkin C.S., Liao L.M., Sinha R., Lopez-carrillo L., Lunet N., Morais S., Aragones N., Moreno V., Vioque J., de la Hera M.G., Ward M.H., Malekzadeh R., Pakseresht M., Hernandez-ramirez R.U., Lopez-cervantes M., Bonzi R., Dalmartello M., Tsugane S., Hidaka A., Camargo M.C., Curado M.P., Zhang Z.-F., Zubair N., Vecchia C.L., Shah S., Boffetta P. |
| سنة النشر: | 2022 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | cancer subsite, cancer subtype, diet, gastric cancer, iron |
| الوصف: | Background: Inconsistent findings have been reported regarding the relationship between dietary iron intake and the risk of gastric cancer (GC). Methods: We pooled data from 11 case‐control studies from the Stomach Cancer Pooling (StoP) Project. Total dietary iron intake was derived from food frequency questionnaires combined with national nutritional tables. We derived the odds ratios (ORs) and 95% confidence intervals (CIs) for quartiles of dietary iron through multivariable unconditional logistic regression models. Secondary analyses stratified by sex, smoking status, caloric intake, anatomical subsite and histological type were performed. Results: Among 4658 cases and 12247 controls, dietary iron intake was inversely associated with GC (per quartile OR 0.88; 95% CI: 0.83–0.93). Results were similar between cardia (OR = 0.85, 95% CI = 0.77–0.94) and non‐cardia GC (OR = 0.87, 95% CI = 0.81–0.94), and for diffuse (OR = 0.79, 95% CI = 0.69–0.89) and intestinal type (OR = 0.88, 95% CI = 0.79–0.98). Iron intake exerted an independent effect from that of smoking and salt intake. Additional adjustment by meat and fruit/vegetable intake did not alter the results. Conclusions: Dietary iron is inversely related to GC, with no difference by subsite or histological type. While the results should be interpreted with caution, they provide evidence against a direct effect of iron in gastric carcinogenesis. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35745285; info:eu-repo/semantics/altIdentifier/wos/WOS:000819096100001; volume:14; issue:12; firstpage:1; lastpage:14; numberofpages:14; journal:NUTRIENTS; https://hdl.handle.net/11585/927082Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85132147793; https://www.mdpi.com/2072-6643/14/12/2555Test |
| DOI: | 10.3390/nu14122555 |
| الإتاحة: | https://doi.org/10.3390/nu14122555Test https://hdl.handle.net/11585/927082Test https://www.mdpi.com/2072-6643/14/12/2555Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.5BC87D99 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/nu14122555 |
|---|