دورية أكاديمية
Assessment of Apolipoprotein(a) Isoform Size Using Phenotypic and Genotypic Methods
| العنوان: | Assessment of Apolipoprotein(a) Isoform Size Using Phenotypic and Genotypic Methods |
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| المؤلفون: | Fogacci F, Di Micoli V, Avagimyan A, Giovannini M, Imbalzano E, Cicero AFG |
| المساهمون: | Fogacci F, Di Micoli V, Avagimyan A, Giovannini M, Imbalzano E, Cicero AFG |
| سنة النشر: | 2023 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | KIV 2, LPA gene, Lp(a), apo(a), apolipoprotein(a), lipoprotein(a) |
| الوصف: | Apolipoprotein(a) (apo(a)) is the protein component that defines lipoprotein(a) (Lp(a)) particles and is encoded by the LPA gene. The apo(a) is extremely heterogeneous in size due to the copy number variations in the kringle-IV type 2 (KIV2) domains. In this review, we aim to discuss the role of genetics in establishing Lp(a) as a risk factor for coronary heart disease (CHD) by examining a series of molecular biology techniques aimed at identifying the best strategy for a possible application in clinical research and practice, according to the current gold standard. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37762189; info:eu-repo/semantics/altIdentifier/wos/WOS:001074161900001; volume:24; issue:18; firstpage:1; lastpage:14; numberofpages:14; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11585/953908Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85172914408; https://www.mdpi.com/1422-0067/24/18/13886Test |
| DOI: | 10.3390/ijms241813886 |
| الإتاحة: | https://doi.org/10.3390/ijms241813886Test https://hdl.handle.net/11585/953908Test https://www.mdpi.com/1422-0067/24/18/13886Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.41576E47 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/ijms241813886 |
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