دورية أكاديمية
Cytotoxic/natural killer cell cuteneous lymphomas: report of EORTC Cutaneous Lymphoma Task Force Workshop
| العنوان: | Cytotoxic/natural killer cell cuteneous lymphomas: report of EORTC Cutaneous Lymphoma Task Force Workshop |
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| المؤلفون: | SANTUCCI Marco, PIMPINELLI Nicola, MASSI Daniela, KADIN Marshall E., MEIJER Chris J. L. M., MÜLLER HERMELINK Hans Konrad, WECHSLER Janine, WILLEMZE Rein, AUDRING Heike, GRAZIA BERNENGO Maria, CERRONI Lorenzo, CHIMENTI Sergio, CHOTT Andreas, DIAZ PEREZ José L., DIPPEL Edgard, DUNCAN Lyn M., FELLER Alfred C., GEERTS Marie Louise, HALLERMANN Christian, KEMPF Werner, RUSSELL JONES Robin, SANDER Christian, BERTI Emilio, PAULLI, MARCO |
| المساهمون: | Santucci, Marco, Pimpinelli, Nicola, Massi, Daniela, KADIN Marshall, E., MEIJER Chris, J. L. M., MÜLLER HERMELINK Hans, Konrad, Paulli, Marco, Wechsler, Janine, Willemze, Rein, Audring, Heike, GRAZIA BERNENGO, Maria, Cerroni, Lorenzo, Chimenti, Sergio, Chott, Andrea, DIAZ PEREZ José, L., Dippel, Edgard, DUNCAN Lyn, M., FELLER Alfred, C., GEERTS Marie, Louise, Hallermann, Christian, Kempf, Werner, RUSSELL JONES, Robin, Sander, Christian, Berti, Emilio |
| سنة النشر: | 2003 |
| المجموعة: | IRIS UNIPV (Università degli studi di Pavia) |
| مصطلحات موضوعية: | CUTANEOUS LYMPHOMA, CYTOTOXIC/NK-CELL LYMPHOMA |
| الوصف: | Cutaneous lymphomas expressing a cytotoxic or natural killer (NK) cell phenotype represent a group of lymphoproliferative disorders for which there is currently much confusion and little consensus regarding the best nomenclature and classification. METHODS: This study analyzes 48 cases of primary cutaneous lymphoma expressing cytotoxic proteins and/or the NK cell marker, CD56. These cases were collected for a workshop of the European Organization for Research and Treatment of Cancer Cutaneous Lymphoma Task Force, to better clarify the clinical, morphologic, and phenotypic features of these uncommon tumors. RESULTS: Several categories with different clinical and pathologic features were delineated: 1) aggressive, CD8+, epidermotropic, cytotoxic T-cell lymphoma; 2) mycosis fungoides, cytotoxic immunophenotype variant; 3) subcutaneous panniculitis-like T-cell lymphoma; 4) NK/T-cell lymphoma, nasal type; 5) CD4+, NK cell lymphoma; 6) blastoid NK cell lymphoma; (7) intravascular NK-like lymphoma; and 8) cytotoxic, peripheral T-cell lymphoma. CONCLUSIONS: Our data show that primary cutaneous cytotoxic/NK cell lymphomas include distinct groups of diseases, clinically, histologically, and biologically. Because the finding of a cytotoxic phenotype often has prognostic significance, the routine use of cytotoxic markers in the diagnosis and classification of cutaneous lymphomas should be expanded. Copyright 2003 American Cancer Society |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/12548603; volume:97; issue:3; firstpage:610; lastpage:627; journal:CANCER; http://hdl.handle.net/11571/133440Test |
| DOI: | 10.1002/cncr.11107 |
| الإتاحة: | https://doi.org/10.1002/cncr.11107Test http://hdl.handle.net/11571/133440Test |
| رقم الانضمام: | edsbas.8C84E886 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/cncr.11107 |
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