التفاصيل البيبلوغرافية
| العنوان: |
Clinical, pathological and immunohistochemical effects of arsenical-ferruginous spa waters on mild-to-moderate psoriatic lesions: a randomized placebo-controlled study. |
| المؤلفون: |
BORRONI, GIOVANNI, BRAZZELLI, VALERIA, ROSSO, RENATO, PAULLI, MARCO, CIOCCA, OLGA, L. Fornara, C. Tinelli |
| المساهمون: |
Borroni, Giovanni, Brazzelli, Valeria, L., Fornara, Rosso, Renato, Paulli, Marco, C., Tinelli, Ciocca, Olga |
| سنة النشر: |
2013 |
| المجموعة: |
IRIS UNIPV (Università degli studi di Pavia) |
| مصطلحات موضوعية: |
Aged, 80 and over, Arsenical, therapeutic use, Balneology, methods, Biological Marker, analysis, Biopsy, Double-Blind Method, Female, Humans, Immersion, Immunohistochemistry, Iron Compound, Italy, Ki-67 Antigen, Male, Middle Aged, Mineral Water, Psoriasi, metabolism/pathology/therapy, Severity of Illness Index, Skin, metabolism/pathology, Time Factors, Treatment Outcome |
| الوصف: |
Thermalism and spa treatments are traditionally considered effective in a number of dermatologic inflammatory conditions, yet there is scarce evidence about spring water effectiveness on psoriasis in a daily setting. We enrolled 34 patients with mild-to-moderate psoriasis in a double-blind, randomized, placebo-contralaterally-controlled trial, to evaluate Levico and Vetriolo arsenical-ferruginous water effectiveness on psoriatic lesions by daily 20-minute wet packing for 12 consecutive days. Clinical, histopathologic and immunohistochemical parameters were considered. A statistically significant difference between spa water-treated lesions and placebo-treated lesions in the same patients was demonstrated for histopathologic and immunohistochemical parameters. Since iron ions have an antiproliferative effect on epithelia, and magnesium ions have an anti-inflammatory effect, Levico and Vetriolo water effectiveness on psoriasis could be addressed to their content of these ions. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
STAMPA |
| اللغة: |
English |
| العلاقة: |
info:eu-repo/semantics/altIdentifier/pmid/23755765; info:eu-repo/semantics/altIdentifier/wos/000321161000023; volume:26; issue:2; firstpage:495; lastpage:501; numberofpages:7; journal:INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY; http://hdl.handle.net/11571/829045Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84881220096 |
| الإتاحة: |
http://hdl.handle.net/11571/829045Test |
| رقم الانضمام: |
edsbas.8E352CC9 |
| قاعدة البيانات: |
BASE |
