دورية أكاديمية

Acute myocardial infarction complicating ischemic stroke: is there room for cangrelor?

التفاصيل البيبلوغرافية
العنوان: Acute myocardial infarction complicating ischemic stroke: is there room for cangrelor?
المؤلفون: Morici N., Nava S., Sacco A., Viola G., Oreglia J., Meani P., Oliva F., Ranucci M., Leonardi S., Rossini R.
المساهمون: Morici, N., Nava, S., Sacco, A., Viola, G., Oreglia, J., Meani, P., Oliva, F., Ranucci, M., Leonardi, S., Rossini, R.
سنة النشر: 2020
المجموعة: IRIS UNIPV (Università degli studi di Pavia)
مصطلحات موضوعية: cangrelor, myocardial infarction, stroke, Adenosine Monophosphate, Aged, 80 and over, Biomarker, Disease Management, Female, Human, Male, Percutaneous Coronary Intervention, Platelet Aggregation Inhibitor, Purinergic P2Y Receptor Antagonist, Time-to-Treatment, Tomography, X-Ray Computed, Treatment Outcome
الوصف: Acute myocardial infarction (AMI) complicating ischemic stroke is a well known and undertreated event. A conservative management is not infrequent in these settings, due to the fear of hemorrhagic complications related to antithrombotic therapy. Notably, an invasive approach with a primary percutaneous coronary intervention (PCI) has been shown to be associated with a lower in-hospital mortality in patients with concomitant ischemic stroke and AMI. The optimal antiplatelet regimen in these cases has been not clearly defined, yet. We report two cases of patients with AMI complicating ischemic stroke, successfully treated with cangrelor infusion, which was started during PCI and maintained up to 48 h at bridge therapy dosage (0.75 mcg/kg/min). Both patients underwent successful PCI in the acute phase, and neither ischemic nor hemorrhagic complications occurred during in-hospital stay.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31066332; info:eu-repo/semantics/altIdentifier/wos/WOS:000470356800001; volume:31; issue:1; firstpage:120; lastpage:123; numberofpages:4; journal:PLATELETS; http://hdl.handle.net/11571/1341481Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85065463127
DOI: 10.1080/09537104.2019.1609663
الإتاحة: https://doi.org/10.1080/09537104.2019.1609663Test
http://hdl.handle.net/11571/1341481Test
رقم الانضمام: edsbas.CAACEB60
قاعدة البيانات: BASE