دورية أكاديمية
Receptor for hyaluronic acid- mediated motility (RHAMM) regulates HT1080 fibrosarcoma cell proliferation via a β-catenin/c-myc signaling axis
| العنوان: | Receptor for hyaluronic acid- mediated motility (RHAMM) regulates HT1080 fibrosarcoma cell proliferation via a β-catenin/c-myc signaling axis |
|---|---|
| المؤلفون: | Kouvidi, Katerina, Berdiaki, Aikaterini, Tzardi, Maria, KAROUSOU, EVGENIA, PASSI, ALBERTO, Nikitovic, Dragana, Tzanakakis, George N. |
| المساهمون: | Kouvidi, Katerina, Berdiaki, Aikaterini, Tzardi, Maria, Karousou, Evgenia, Passi, Alberto, Nikitovic, Dragana, Tzanakakis, George N. |
| سنة النشر: | 2016 |
| المجموعة: | IRInSubria - Institutional Repository Insubria (Università degli Studi dell’Insubria) |
| مصطلحات موضوعية: | ERK1/2, Fibrosarcoma cell proliferation, LMWHA, RHAMM, β-Catenin, Active Transport, Cell Nucleu, Antigens, CD44, Cell Line, Tumor, Extracellular Matrix Protein, Fibrosarcoma, Human, Proto-Oncogene Proteins c-myc, beta Catenin, Cell Proliferation, Signal Transduction |
| الوصف: | High levels of hyaluronan (HA) synthesis in various cancer tissues, including sarcomas, are correlated with tumorigenesis and malignant transformation. RHAMM (receptor for hyaluronic acid-mediated motility) is overexpressed during tumor development in different malignancies. β-Catenin is a crucial downstream mediator of the Wnt signaling cascade which facilitates carcinogenic events characterized by deregulated cell proliferation. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/26825774; info:eu-repo/semantics/altIdentifier/wos/WOS:000371549000019; volume:1860; issue:4; firstpage:814-24; lastpage:824; numberofpages:11; journal:BIOCHIMICA ET BIOPHYSICA ACTA; http://hdl.handle.net/11383/2049143Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84969373529 |
| DOI: | 10.1016/j.bbagen.2016.01.019 |
| الإتاحة: | https://doi.org/10.1016/j.bbagen.2016.01.019Test http://hdl.handle.net/11383/2049143Test |
| رقم الانضمام: | edsbas.7984910B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.bbagen.2016.01.019 |
|---|