دورية أكاديمية
Antifungal susceptibility testing in Candida, Aspergillus and Cryptococcus infections: are the MICs useful for clinicians?
| العنوان: | Antifungal susceptibility testing in Candida, Aspergillus and Cryptococcus infections: are the MICs useful for clinicians? |
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| المؤلفون: | Bassetti, M, Vena, A, Bouza, E, Peghin, M, Muñoz, P, Righi, E, Pea, F, Lackner, M, Lass-Flörl, C |
| المساهمون: | Bassetti, M, Vena, A, Bouza, E, Peghin, M, Muñoz, P, Righi, E, Pea, F, Lackner, M, Lass-Flörl, C |
| سنة النشر: | 2020 |
| المجموعة: | IRInSubria - Institutional Repository Insubria (Università degli Studi dell’Insubria) |
| مصطلحات موضوعية: | Antifungal, Aspergillu, Azole resistance, Candida, Clinical implication, Cryptococcu, Echinocandin resistance, MIC, Antifungal Agent, Comorbidity, Fungi, Human, Invasive Fungal Infection, Microbial Sensitivity Test, Risk Factor, Drug Resistance, Fungal |
| الوصف: | Background: Invasive fungal infections (IFIs) represent a global issue and affect various patient populations. In recent years, resistant fungal isolates showing increased azole or echinocandin MICs have been reported, and their potential clinical impact has been investigated. Aims: To provide an update on the epidemiology of resistance among fungi (e.g., Candida spp., Aspergillus spp., and Cryptococcus spp.) and to offer a critical appraisal of the relevant literature regarding the impact of MICs on clinical outcome in patients with IFI. Sources: PubMed search with relevant keywords along with a personal collection of relevant publications. Content: Although antifungal resistance has been associated with a poorer response to antifungal therapy in various studies, other factors such as comorbidities, septic shock and source of infection appear to be key determinants affecting the clinical outcome of patients with IFI. Implications: Future international collaborative studies are required to tease out the relative contribution of in vitro antifungal resistance on patient outcomes, thus enabling the optimization of IFI management. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/32120042; info:eu-repo/semantics/altIdentifier/wos/WOS:000550762300010; volume:26; issue:8; firstpage:1024; lastpage:1033; numberofpages:10; journal:CLINICAL MICROBIOLOGY AND INFECTION; https://hdl.handle.net/11383/2140674Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85083321665 |
| DOI: | 10.1016/j.cmi.2020.02.017 |
| الإتاحة: | https://doi.org/10.1016/j.cmi.2020.02.017Test https://hdl.handle.net/11383/2140674Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.7FD6DDC1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.cmi.2020.02.017 |
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