دورية أكاديمية

Evaluation of Patients with Fibrotic Interstitial Lung Disease: Preliminary results from the Turk-UIP Study

التفاصيل البيبلوغرافية
العنوان: Evaluation of Patients with Fibrotic Interstitial Lung Disease: Preliminary results from the Turk-UIP Study
المؤلفون: Müsellim, Benan, Moğulkoç, Nesrin, Uzun, Oğuz, Tokgöz Akyıl, Fatma, Türktaş, Haluk, Özdemir Kumbasar, Özlem, Okumuş, Gülfer, Öğüş, Candan, Dirol, Hülya, Zamani, Adil, Sevim, Tülin, Annakkaya, Ali Nihat, Akıncı Özyürek, Berna, Hanta, İsmail, Aydemir, Yusuf, Çakır Edis, Ebru, Kurt, Bahar, Tertemiz, Kemal Can, Tabak, Levent, Yazıcı, Onur, Erdoğan, Yurdanur, Ateş, Güngör, Türker, Hatice, Salepci, Banu, Hazar, Armağan, Niksarlıoğlu, Elif Yelda, Yılmaz Kara, Bilge, Köktürk, Nurdan, Kalpaklıoğlu, Füsun, Uzel, Işıl, Özsu, Savaş, Atahan, Ersan, Fendoğlu, Türkan Zeynep, Yılmaz, Süreyya, Başyiğit, İlknur, Çamsarı, Güngör, Tuncay, Esin, Uçar Yılmazel, Elif, Kanmaz, Dilek, Ekici, Aydanur, Topçu, Füsun, Uzaslan, Esra, Bozkuş, Fulsen, Argun Barış, Serap, Duru, Serap, Altınışık, Göksel, Bingöl, Züleyha, Tunacı, Atadan, Savaş, Recep, Alper, Fatih, Bayraktaroğlu, Selen, Selçuk Can, Tuba, Demir, Ali Aslan
المساهمون: Selçuk Can, Tuba
بيانات النشر: AVES, BUYUKDERE CAD 105-9, MECIDIYEKOY, SISLI, ISTANBUL 34394, TURKEY
سنة النشر: 2021
المجموعة: IGU Institutional Open Access Repository (İstanbul Gelişim University)
مصطلحات موضوعية: Fibrotic interstitial lung diseases, idiopathic pulmonary fibrosis, usual interstitial pneumonia
الوصف: OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). This study aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with and without IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP pattern on thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according to the 2011 ATS/ERS/JRS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recorded by researchers was evaluated by radiology and the clinical decision board. RESULTS: A total of 336 patients (253 men, 83 women, age 65.8±9.0 years) were evaluated. Of the patients with sufficient data for diagnosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonary fibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patients with definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex (p<0.001), smoking history (p<0.001), and the presence of clubbing (p=0.001) were significantly high in patients with IPF. None of the women <50 years and none of the men <50 years of age without a smoking history were diagnosed with IPF. Presence of at least 1 of the symptoms suggestive of CTD, erythrocyte sedimentation rate (ESR), and antinuclear antibody (FANA) positivity rates were significantly higher in the non-IPF group (p<0.001, p=0.029, p=0.009, respectively). CONCLUSION: The rate of IPF among patients with fibrotic ILD was 50%. In the differential diagnosis of IPF, sex, smoking habits, and the presence of clubbing are important. The presence of symptoms related ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
تدمد: 2149-2530
العلاقة: Turkish Thoracic Journal; Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11363/4953Test; 22; 102; 109
الإتاحة: https://hdl.handle.net/11363/4953Test
حقوق: info:eu-repo/semantics/openAccess ; Attribution-NonCommercial-NoDerivs 3.0 United States ; http://creativecommons.org/licenses/by-nc-nd/3.0/usTest/
رقم الانضمام: edsbas.4FA476D5
قاعدة البيانات: BASE