دورية أكاديمية
Recoverability of reproductive system in patients with concomitant hyperandrogenism
| العنوان: | Recoverability of reproductive system in patients with concomitant hyperandrogenism |
|---|---|
| المؤلفون: | Saidova, Ravzat Abdulatipovna |
| المصدر: | Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics ; ISSN 1330-0091 (Print) ; Volume 25 ; Issue 4 |
| سنة النشر: | 2016 |
| المجموعة: | Hrčak - Portal of scientific journals of Croatia / Portal znanstvenih časopisa Republike Hrvatske |
| مصطلحات موضوعية: | hyperandrogenism, anovulation, luteal phase defi ciency, polycystic ovary syndrome, testosterone, dihydrotestosterone, infertility |
| الوصف: | Introduction. Adrenal hyperandrogenism (HA) exerts a negative effect on the women’s reproductive system (RS), while ovarian HA is preconditioned by the anovulation state. There are contradictory opinions on the infl uence of different androgens on the functions of women’s reproductive system. The main criteria of the assessment and importance of these factors remain undefined. Aim. In total, 105 women were examined and treated in the study, including a control group of women aged 19 to 37 (mean age 27,39±0,75), and patients with menstrual (opso- and oligomenorrhea) and reproductive (infertility and miscarriage) dysfunctions. Methods. The hormonal panel tests were also performed in the course of the menstrual cycle, on days 5–7 and 21–23, assessing the level of secretion of peptide and steroid sex hormones. Results. Combined HA is one of the leading pathogenic causes of menstrual and reproductive dysfunctions. Anovulation state causes an increase in the level of the main androgens, and the luteal phase deficiency is a consequence of the negative impact of HA. Individual pathogenesis-based therapy, allows recovering ovulation and securing pregnancy against a background of normalization of androgen metabolism and other indicators of the reproductive system functioning. Conclusion. The criteria for differential diagnostics of hyperandrogenic states and assessment of reproductive dysfunctions allows finding an individual treatment pattern. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://hrcak.srce.hr/251505Test |
| الإتاحة: | https://hrcak.srce.hr/251505Test https://hrcak.srce.hr/file/365646Test |
| حقوق: | info:eu-repo/semantics/openAccess ; Access to all medical professionals. Free downloading of summaries and full text from all volumes. Subcription is not necessary for admittance to portal and downloading. Papers published in this journal are free for personal and educational needs, with respect of author's and publisher's rights. |
| رقم الانضمام: | edsbas.C096A5BC |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |