المؤلفون: Barnes, Daniel R, Silvestri, Valentina, Leslie, Goska, McGuffog, Lesley, Dennis, Joe, Yang, Xin, Adlard, Julian, Agnarsson, Bjarni A, Ahmed, Munaza, Aittomäki, Kristiina, Andrulis, Irene L, Arason, Adalgeir, Arnold, Norbert, Auber, Bernd, Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B, Barrowdale, Daniel, Barwell, Julian, Belotti, Muriel, Benitez, Javier, Berthet, Pascaline, Boonen, Susanne E, Borg, Åke, Bozsik, Aniko, Brady, Angela F, Brennan, Paul, Brewer, Carole, Brunet, Joan, Bucalo, Agostino, Buys, Saundra S, Caldés, Trinidad, Caligo, Maria A, Campbell, Ian, Cassingham, Hayley, Christensen, Lise Lotte, Cini, Giulia, Claes, Kathleen B M, Cook, Jackie, Coppa, Anna, Cortesi, Laura, Damante, Giuseppe, Darder, Esther, Davidson, Rosemarie, de la Hoya, Miguel, De Leeneer, Kim, de Putter, Robin, Del Valle, Jesús, Diez, Orland, Ding, Yuan Chun, Domchek, Susan M, Donaldson, Alan, Eason, Jacqueline, Eeles, Ros, Engel, Christoph, Evans, D Gareth, Feliubadaló, Lidia, Fostira, Florentia, Frone, Megan, Frost, Debra, Gallagher, David, Gehrig, Andrea, Giraud, Sophie, Glendon, Gord, Godwin, Andrew K, Goldgar, David E, Greene, Mark H, Gregory, Helen, Gross, Eva, Hahnen, Eric, Hamann, Ute, Hansen, Thomas V O, Hanson, Helen, Hentschel, Julia, Horvath, Judit, Izatt, Louise, Izquierdo, Angel, James, Paul A, Janavicius, Ramunas, Jensen, Uffe Birk, Johannsson, Oskar Th, John, Esther M, Kramer, Gero, Kroeldrup, Lone, Kruse, Torben A, Lautrup, Charlotte, Lazaro, Conxi, Lesueur, Fabienne, Lopez-Fernández, Adria, Mai, Phuong L, Manoukian, Siranoush, Matrai, Zoltan, Matricardi, Laura, Maxwell, Kara N, Mebirouk, Noura, Meindl, Alfons, Montagna, Marco, Monteiro, Alvaro N, Morrison, Patrick J, Muranen, Taru A, Murray, Alex, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, Nguyen-Dumont, Tu, Niederacher, Dieter, Olah, Edith, Olopade, Olufunmilayo I, Palli, Domenico, Parsons, Michael T, Pedersen, Inge Sokilde, Peissel, Bernard, Perez-Segura, Pedro, Peterlongo, Paolo, Petersen, Annabeth H, Pinto, Pedro, Porteous, Mary E, Pottinger, Caroline, Pujana, Miquel Angel, Radice, Paolo, Ramser, Juliane, Rantala, Johanna, Robson, Mark, Rogers, Mark T, Rønlund, Karina, Rump, Andreas, Sánchez de Abajo, Ana María, Shah, Payal D, Sharif, Saba, Side, Lucy E, Singer, Christian F, Stadler, Zsofia, Steele, Linda, Stoppa-Lyonnet, Dominique, Sutter, Christian, Tan, Yen Yen, Teixeira, Manuel R, Teulé, Alex, Thull, Darcy L, Tischkowitz, Marc, Toland, Amanda E, Tommasi, Stefania, Toss, Angela, Trainer, Alison H, Tripathi, Vishakha, Valentini, Virginia, van Asperen, Christi J, Venturelli, Marta, Viel, Alessandra, Vijai, Joseph, Walker, Lisa, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Whaite, Anna, Zanna, Ines, Offit, Kenneth, Thomassen, Mads, Couch, Fergus J, Schmutzler, Rita K, Simard, Jacques, Easton, Douglas F, Chenevix-Trench, Georgia, Antoniou, Antonis C, Ottini, Laura

المساهمون: 1Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. 2Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy. 3Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, UK. 4Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland. 5School of Medicine, University of Iceland, Reykjavik, Iceland. 6North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK. 7Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. 8Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada. 9Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. 10BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 11Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany. 12Institute of Clinical Molecular Biology, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany. 13Department of Human Genetics, Hannover Medical School, Hannover, Germany. 14Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. 15Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology, Vall d'Hebron Hospital Campus, Barcelona, Spain. 16Department of Medical Oncology, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain. 17Leicestershire Clinical Genetics Service, University Hospitals of Leicester NHS Trust, Leicester, UK. 18Service de Génétique, Institut Curie, Paris, France. 19Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. 20Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. 21Département de Biopathologie, Centre François Baclesse, Caen, France. 22Department of Clinical Genetics, Odense University Hospital, Odense, Denmark. 23Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden. 24Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. 25North West Thames Regional Genetics Service, London North West University Healthcare NHS Trust, Northwick Park Hospital, Harrow, UK. 26Northern Genetics Service, Newcastle Hospitals NHS Foundation Trust, Newcastle, UK. 27Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, UK. 28Hereditary Cancer Program, Oncobell-IDIBELL-IGTP, Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 29Department of Internal Medicine, Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA. 30Molecular Oncology Laboratory, CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain. 31SOD Genetica Molecolare, University Hospital, Pisa, Italy. 32Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. 33Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia. 34Department of Internal Medicine, Division of Human Genetics, The Ohio State University Wexner Medical Center, Columbus, OH, USA. 35Division of Surgical Oncology, National Cancer Centre, Singapore, Singapore. 36Division of Functional Onco-Genomics and Genetics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy. 37Centre for Medical Genetics, Ghent University, Gent, Belgium. 38Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK. 39Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy. 40Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy. 41Department of Medicine, University of Udine, Udine, Italy. 42Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, UK. 43Area of Clinical and Molecular Genetics, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain. 44Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. 45Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA. 46Clinical Genetics Department, St Michael's Hospital, Bristol, UK. 47Nottingham Clinical Genetics Service, Nottingham University Hospitals NHS Trust, Nottingham, UK. 48Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK. 49Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. 50LIFE-Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany. 51Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. 52North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. 53Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece. 54Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA. 55Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and St James's Hospital, Dublin, Eire. 56Department of Human Genetics, University Würzburg, Würzburg, Germany. 57Service de Génétique, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France. 58Department of Pathology and Laboratory Medicine, University of Kansas, Medical Center, Kansas City, KS, USA. 59Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. 60North of Scotland Regional Genetics Service, NHS Grampian & University of Aberdeen, Foresterhill, Aberdeen, UK. 61Department of Gynecology and Obstetrics, University of Munich, Munich, Germany. 62Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany. 63Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany. 64Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. 65Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 66Southwest Thames Regional Genetics Service, St George's Hospital, London, UK. 67Institute of Human Genetics, University Hospital Leipzig, Leipzig, Germany. 68Institute of Human Genetics, University of Münster, Münster, Germany. 69Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK. 70Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. 71Faculty of Medicine, Institute of Biomedical Sciences, Department of Human and Medical Genetics, Vilnius University, Vilnius, Lithuania. 72State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania. 73Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark. 74Department of Oncology, Landspitali University Hospital, Reykjavik, Iceland. 75Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA. 76Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. 77Department of Urology, Medical University of Vienna, Vienna, Austria. 78Department of Clinical Genetics, Aalborg University Hospital, Aalborg, Denmark. 79Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark. 80Institut Curie, Paris, France. 81Mines ParisTech, Fontainebleau, France. 82Genetic Epidemiology of Cancer Team, Inserm U900, Paris, France. 83Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. 84Department of Surgery, National Institute of Oncology, Budapest, Hungary. 85Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy. 86Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. 87Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA. 88Northern Ireland Regional Genetics Centre, Belfast City Hospital, Belfast, UK. 89Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. 90All Wales Medical Genetics Services, University Hospital of Wales, Cardiff, UK. 91Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia. 92Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia. 93Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany. 94Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA. 95Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy. 96Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. 97Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark. 98Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. 99Genome Diagnostics Program, IFOM-the FIRC Institute of Molecular Oncology, Milan, Italy. 100Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. 101Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. 102South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK. 103Translational Research Laboratory, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 104Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy. 105Division of Gynaecology and Obstetrics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany. 106Clinical Genetics, Karolinska Institutet, Stockholm, Sweden. 107Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 108Institute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. 109Servicio de Análisis Clínicos y Bioquímica Clínica, Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria , Las Palmas de Gran Canaría, Spain. 110West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Birmingham, UK. 111Princess Anne Hospital, Southampton, UK. 112Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. 113Department of Tumour Biology, INSERM U830, Paris, France. 114Université Paris Descartes, Paris, France. 115Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. 116Dept of OB/GYN, Medical University of Vienna, Vienna, Austria. 117Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal. 118Department of Medicine, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. 119Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, QC, Canada. 120Department of Medical Genetics, University of Cambridge, Cambridge, UK. 121Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA. 122IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy. 123Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia. 124Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. 125Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 126Oxford Regional Genetics Service, Churchill Hospital, Oxford, UK. 127Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany. 128Liverpool Centre for Genomic Medicine, Liverpool Women's NHS Foundation Trust, Liverpool, UK. 129Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. 130Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany. 131Genomics Center, Centre Hospitalier Universitaire de Québec-Université Laval Research Center, Québec City, QC, Canada. 132Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

المصدر: Journal of the National Cancer Institute ; 114 ; 1 ; 109 ; 122 ; United States ; United Kingdom

مصطلحات موضوعية: Blöðruhálskirtilskrabbamein, Gen, Genes, BRCA1, BRCA2, Prostatic Neoplasms, Genetic Predisposition to Disease

العلاقة: https://academic.oup.com/jnci/article/114/1/109/6329642Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755508Test/; Barnes DR, Silvestri V, Leslie G, et al. Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores. J Natl Cancer Inst. 2022;114(1):109-122. doi:10.1093/jnci/djab147; http://hdl.handle.net/2336/622100Test; Journal of the National Cancer Institute

الإتاحة: https://doi.org/10.1093/jnci/djab147Test
http://hdl.handle.net/2336/622100Test

المؤلفون: Patel, Vivek L, Busch, Evan L, Friebel, Tara M, Cronin, Angel, Leslie, Goska, McGuffog, Lesley, Adlard, Julian, Agata, Simona, Agnarsson, Bjarni A, Ahmed, Munaza, Aittomäki, Kristiina, Alducci, Elisa, Andrulis, Irene L, Arason, Adalgeir, Arnold, Norbert, Artioli, Grazia, Arver, Brita, Auber, Bernd, Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B, Barnes, Daniel R, Barroso, Alicia, Barrowdale, Daniel, Belotti, Muriel, Benitez, Javier, Bertelsen, Brigitte, Blok, Marinus J, Bodrogi, Istvan, Bonadona, Valérie, Bonanni, Bernardo, Bondavalli, Davide, Boonen, Susanne E, Borde, Julika, Borg, Ake, Bradbury, Angela R, Brady, Angela, Brewer, Carole, Brunet, Joan, Buecher, Bruno, Buys, Saundra S, Cabezas-Camarero, Santiago, Caldés, Trinidad, Caliebe, Almuth, Caligo, Maria A, Calvello, Mariarosaria, Campbell, Ian G, Carnevali, Ileana, Carrasco, Estela, Chan, Tsun L, Chu, Annie T W, Chung, Wendy K, Claes, Kathleen B M, Collaborators, Gemo Study, Collaborators, Embrace, Cook, Jackie, Cortesi, Laura, Couch, Fergus J, Daly, Mary B, Damante, Giuseppe, Darder, Esther, Davidson, Rosemarie, de la Hoya, Miguel, Puppa, Lara Della, Dennis, Joe, Díez, Orland, Ding, Yuan Chun, Ditsch, Nina, Domchek, Susan M, Donaldson, Alan, Dworniczak, Bernd, Easton, Douglas F, Eccles, Diana M, Eeles, Rosalind A, Ehrencrona, Hans, Ejlertsen, Bent, Engel, Christoph, Evans, D Gareth, Faivre, Laurence, Faust, Ulrike, Feliubadaló, Lídia, Foretova, Lenka, Fostira, Florentia, Fountzilas, George, Frost, Debra, García-Barberán, Vanesa, Garre, Pilar, Gauthier-Villars, Marion, Géczi, Lajos, Gehrig, Andrea, Gerdes, Anne-Marie, Gesta, Paul, Giannini, Giuseppe, Glendon, Gord, Godwin, Andrew K, Goldgar, David E, Greene, Mark H, Gutierrez-Barrera, Angelica M, Hahnen, Eric, Hamann, Ute, Hauke, Jan, Herold, Natalie, Hogervorst, Frans B L, Honisch, Ellen, Hopper, John L, Hulick, Peter J, Investigators, KConFab, Investigators, Hebon, Izatt, Louise, Jager, Agnes, James, Paul, Janavicius, Ramunas, Jensen, Uffe Birk, Jensen, Thomas Dyrso, Johannsson, Oskar Th, John, Esther M, Joseph, Vijai, Kang, Eunyoung, Kast, Karin, Kiiski, Johanna I, Kim, Sung-Won, Kim, Zisun, Ko, Kwang-Pil, Konstantopoulou, Irene, Kramer, Gero, Krogh, Lotte, Kruse, Torben A, Kwong, Ava, Larsen, Mirjam, Lasset, Christine, Lautrup, Charlotte, Lazaro, Conxi, Lee, Jihyoun, Lee, Jong Won, Lee, Min Hyuk, Lemke, Johannes, Lesueur, Fabienne, Liljegren, Annelie, Lindblom, Annika, Llovet, Patricia, Lopez-Fernández, Adria, Lopez-Perolio, Irene, Lorca, Victor, Loud, Jennifer T, Ma, Edmond S K, Mai, Phuong L, Manoukian, Siranoush, Mari, Veronique, Martin, Lynn, Matricardi, Laura, Mebirouk, Noura, Medici, Veronica, Meijers-Heijboer, Hanne E J, Meindl, Alfons, Mensenkamp, Arjen R, Miller, Clare, Gomes, Denise Molina, Montagna, Marco, Mooij, Thea M, Moserle, Lidia, Mouret-Fourme, Emmanuelle, Mulligan, Anna Marie, Nathanson, Katherine L, Navratilova, Marie, Nevanlinna, Heli, Niederacher, Dieter, Nielsen, Finn C Cilius, Nikitina-Zake, Liene, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Ong, Kai-Ren, Osorio, Ana, Ott, Claus-Eric, Palli, Domenico, Park, Sue K, Parsons, Michael T, Pedersen, Inge Sokilde, Peissel, Bernard, Peixoto, Ana, Pérez-Segura, Pedro, Peterlongo, Paolo, Petersen, Annabeth Høgh, Porteous, Mary E, Pujana, Miguel Angel, Radice, Paolo, Ramser, Juliane, Rantala, Johanna, Rashid, Muhammad U, Rhiem, Kerstin, Rizzolo, Piera, Robson, Mark E, Rookus, Matti A, Rossing, Caroline M, Ruddy, Kathryn J, Santos, Catarina, Saule, Claire, Scarpitta, Rosa, Schmutzler, Rita K, Schuster, Hélène, Senter, Leigha, Seynaeve, Caroline M, Shah, Payal D, Sharma, Priyanka, Shin, Vivian Y, Silvestri, Valentina, Simard, Jacques, Singer, Christian F, Skytte, Anne-Bine, Snape, Katie, Solano, Angela R, Soucy, Penny, Southey, Melissa C, Spurdle, Amanda B, Steele, Linda, Steinemann, Doris, Stoppa-Lyonnet, Dominique, Stradella, Agostina, Sunde, Lone, Sutter, Christian, Tan, Yen Y, Teixeira, Manuel R, Teo, Soo Hwang, Thomassen, Mads, Tibiletti, Maria Grazia, Tischkowitz, Marc, Tognazzo, Silvia, Toland, Amanda E, Tommasi, Stefania, Torres, Diana, Toss, Angela, Trainer, Alison H, Tung, Nadine, van Asperen, Christi J, van der Baan, Frederieke H, van der Kolk, Lizet E, van der Luijt, Rob B, van Hest, Liselotte P, Varesco, Liliana, Varon-Mateeva, Raymonda, Viel, Alessandra, Vierstrate, Jeroen, Villa, Roberta, von Wachenfeldt, Anna, Wagner, Philipp, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Weitzel, Jeffrey N, Wieme, Greet, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yoon, Sook-Yee, Zanzottera, Cristina, Zorn, Kristin K, D'Amico, Anthony V, Freedman, Matthew L, Pomerantz, Mark M, Chenevix-Trench, Georgia, Antoniou, Antonis C, Neuhausen, Susan L, Ottini, Laura, Nielsen, Henriette Roed, Rebbeck, Timothy R

المساهمون: 1Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts. 2Harvard T.H. Chan School of Public Health, Boston, Massachusetts. 3Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. 4Dana-Farber Cancer Institute. Boston, Massachusetts. 5Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. 6Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, United Kingdom. 7Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. 8Department of Pathology, Landspitali University Hospital, 101, Reykjavik, Iceland. 9School of Medicine, University of Iceland, Reykjavik, Iceland. 10North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom. 11Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. 12Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada. 13Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. 14BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 15Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany. 16ULSS 3 Serenissima, U.O.C. Oncologia ed Ematologia Oncologica, Mirano, Venice, Italy. 17Department of Oncology, Karolinska Institutet, Stockholm, Sweden. 18Institute of Human Genetics, Hannover Medical School, Hannover, Germany. 19Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori di Milano, Milan, Italy. 20High Risk and Cancer Prevention Group, Vall d'Hebron Institute of Oncology, University Hospital Vall d'Hebron, Barcelona, Spain. 21Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. 22Service de Génétique, Institut Curie, Paris, France. 23Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. 24Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. 25Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 26Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands. 27Department of Chemotherapy, National Institute of Oncology, Budapest, Hungary. 28Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France. 29Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, Milan, Italy. 30Clinical Genetic Unit, Department of Paediatrics, Zealand University Hospital, Roskilde, Denmark. 31Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany. 32Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. 33Center for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany. 34Department of Oncology, Lund University and Skåne University Hospital, Lund, Sweden. 35Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. 36North West Thames Regional Genetics Service, Kennedy Galton Centre, The North West London Hospitals NHS Trust, Middlesex, United Kingdom. 37Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom. 38Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, CIBERONC, Girona, Spain. 39Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah. 40Department of Oncology, Hospital Clinico San Carlos, IdISSC, Madrid, Spain. 41Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. 42Institute of Human Genetics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany. 43Section of Molecular Genetics, Department of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy. 44Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. 45Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia. 46UO Anatomia Patologica, Ospedale di Circolo-Università dell'Insubria, Varese, Italy. 47Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Centre, Happy Valley, Hong Kong. 48Department of Pathology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong. 49Departments of Pediatrics and Medicine, Columbia University, New York, New York. 50Centre for Medical Genetics, Ghent University, Ghent, Belgium. 51Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom. 52Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy. 53Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota. 54Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania. 55Department of Medical and Biological Sciences, University of Udine, Udine, Italy. 56Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, United Kingdom. 57Division of Functional Onco-genomics and Genetics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy. 58Oncogenetics Group, Clinical and Molecular Genetics Area, Vall d'Hebron Institute of Oncology (VHIO), University Hospital, Barcelona, Spain. 59Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California. 60Department of Gynecology and Obstetrics, Ludwig Maximilian University of Munich, Munich, Germany. 61Clinical Genetics Department, St Michael's Hospital, Bristol, United Kingdom. 62Institute of Human Genetics, University of Münster, Münster, Germany. 63Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom. 64Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom. 65Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, United Kingdom. 66Department of Clinical Genetics, Lund University Hospital, Lund, Sweden. 67Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 68Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. 69LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany. 70Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health and Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom. 71Manchester Centre for Genomic Medicine, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust and Manchester Academic Health Science Centre, Manchester, United Kingdom. 72Unité d'oncogénétique, Centre de Lutte Contre le Cancer, Centre Georges-François Leclerc, Dijon, France. 73Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany. 74Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 75Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. 76Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Athens, Greece. 77Second Department of Medical Oncology, EUROMEDICA General Clinic of Thessaloniki, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece. 78Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University of Würzburg, Würzburg, Germany. 79Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark. 80Service Régional Oncogénétique Poitou-Charentes, CH Niort, Niort, France. 81Department of Molecular Medicine, University La Sapienza, Rome, Italy. 82Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kansas. 83Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah. 84Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland. 85Department of Breast Medical Oncology and Clinical Genetics Program, University of Texas MD Anderson Cancer Center, Houston, Texas. 86Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. 87Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands. 88Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany. 89Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia. 90Center for Medical Genetics, NorthShore University HealthSystem, Evanston, Illinois. 91The University of Chicago Pritzker School of Medicine, Chicago, Illinois. 92The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), Coordinating center: The Netherlands Cancer Institute, Amsterdam, the Netherlands. 93Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom. 94Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands. 95Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. 96Hematology, Oncology and Transfusion Medicine Center, Department of Molecular and Regenerative Medicine, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania. 97Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark. 98Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. 99Department of Oncology, Landspitali University Hospital, Reykjavik, Iceland. 100Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California. 101Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York. 102Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea. 103Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden, Germany. 104Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. 105Department of Surgery, Daerim Saint Mary's Hospital, Seoul, Korea. 106Department of Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. 107Department of Preventive Medicine, Gacheon University College of Medicine, Incheon, Republic of Korea. 108Department of Urology, Medical University of Vienna, Vienna, Austria. 109Department of Clinical Genetics, Odense University Hospital, Odense, Denmark. 110Department of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong. 111Department of Surgery, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong. 112Department of Clinical Genetics, Aalborg University Hospital, Aalborg, Denmark. 113Department of Surgery, Soonchunhyang University College of Medicine and Soonchunhyang University Hospital, Seoul, Korea. 114Department of Surgery, Ulsan University College of Medicine and Asan Medical Center, Seoul, Korea. 115Institute of Human Genetics, University Hospital Leipzig, Leipzig, Germany. 116Genetic Epidemiology of Cancer Team, Inserm U900, Paris, France. 117Institut Curie, Paris, France. 118Mines ParisTech, Fontainebleau, France. 119Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. 120Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden. 121Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. 122Département d'Hématologie-Oncologie Médicale, Centre Antoine Lacassagne, Nice, France. 123Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom. 124Department of Clinical Genetics, VU University Medical Center, Amsterdam, the Netherlands. 125Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands. 126Department of Clinical Genetics, Alder Hey Hospital, Liverpool, United Kingdom. 127Service de Biologie de la Reproduction, Cytogénétique et Génétique Médicale, CHI Poissy - Saint Germain, Poissy, France. 128Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. 129Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. 130Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada. 131Latvian Biomedical Research and Study Centre, Riga, Latvia. 132Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York. 133Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. 134Center for Clinical Cancer Genetics, The University of Chicago, Chicago, Illinois. 135West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Birmingham, United Kingdom. 136Institute for Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. 137Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy. 138Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea. 139Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea. 140Cancer Research Institute, Seoul National University, Seoul, Korea. 141Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. 142Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark. 143Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. 144Genome Diagnostics Program, IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. 145South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom. 146Translational Research Laboratory, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 147Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, in Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. 148Division of Gynaecology and Obstetrics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany. 149Clinical Genetics, Karolinska Institutet, Stockholm, Sweden. 150Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan. 151Department of Oncology, Mayo Clinic, Rochester, Minnesota. 152Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa, Italy. 153Unité d'Oncogénétique, Centre de Lutte Contre le Cancer Paul Strauss, Strasbourg, France. 154Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio. 155Department of Internal Medicine, Division of Oncology, University of Kansas Medical Center, Westwood, Kansas. 156Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval, Research Centre, Québec City, Québec, Canada. 157Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. 158Medical Genetics Unit, St George's, University of London, London, United Kingdom. 159INBIOMED, Faculty of Medicine/CONICET and CEMIC, Department of Clinical Chemistry, Medical Direction, University of Buenos Aires, Buenos Aires, Argentina. 160Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia. 161Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia. 162Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany. 163Department of Tumour Biology, INSERM U830, Paris, France. 164Université Paris Descartes, Paris, France. 165Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 166Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. 167Department of OB/GYN, Medical University of Vienna, Vienna, Austria. 168Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal. 169Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia. 170Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia. 171Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Quebec, Canada. 172Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom. 173Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio. 174Istituto Nazionale Tumori 'Giovanni Paolo II, Bari, Italy. 175Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia. 176Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts. 177Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. 178Department of Medical Genetics, University Medical Center, Utrecht, the Netherlands. 179Clinical Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. 180Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) AOU San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy. 181Department of Women's Health, Tubingen University Hospital, Tubingen, Germany. 182Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany. 183Clinical Cancer Genetics, City of Hope, Duarte, California. 184Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Selangor, Malaysia. 185Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Timothy_Rebbeck@dfci.harvard.edu.

المصدر: Cancer research ; 80 ; 3 ; 624 ; 638 ; United Kingdom ; United States

مصطلحات موضوعية: Gen, Blöðruhálskirtilskrabbamein, Genes, BRCA1, BRCA2, Prostatic Neoplasms

العلاقة: https://cancerres.aacrjournals.org/content/80/3/624.longTest; https://cancerres.aacrjournals.org/content/canres/80/3/624.full.pdfTest; Patel VL, Busch EL, Friebel TM, et al. Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Cancer Res. 2020;80(3):624–638. doi:10.1158/0008-5472.CAN-19-1840; http://hdl.handle.net/2336/621345Test; Cancer research

الإتاحة: https://doi.org/10.1158/0008-5472.CAN-19-1840Test
http://hdl.handle.net/2336/621345Test

المؤلفون: Silvestri, Valentina, Barrowdale, Daniel, Mulligan, Anna Marie, Neuhausen, Susan L, Fox, Stephen, Karlan, Beth Y, Mitchell, Gillian, James, Paul, Thull, Darcy L, Zorn, Kristin K, Carter, Natalie J, Fountzilas, George, Perkins, Jo, Adlard, Julian, Izatt, Louise, Platte, Radka, Eeles, Ros, Ellis, Steve, Pasini, Barbara, Giannini, Giuseppe, Rizzolo, Piera, Ramus, Susan J, Russo, Antonio, Cortesi, Laura, Papi, Laura, Nathanson, Katherine L, Varesco, Liliana, Palli, Domenico, Zanna, Ines, Savarese, Antonella, Radice, Paolo, Manoukian, Siranoush, John, Esther M, Peissel, Bernard, Barile, Monica, Bonanni, Bernardo, Viel, Alessandra, Domchek, Susan M, Pensotti, Valeria, Tommasi, Stefania, Peterlongo, Paolo, Weitzel, Jeffrey N, Osorio, Ana, Southey, Melissa, Benitez, Javier, McGuffog, Lesley, Healey, Sue, Gerdes, Anne-Marie, Ejlertsen, Bent, Rebbeck, Timothy R, Hansen, Thomas V O, Steele, Linda, Ding, Yuan Chun, Tung, Nadine, Easton, Douglas F, Janavicius, Ramunas, Goldgar, David E, Buys, Saundra S, Daly, Mary B, Bane, Anita, Terry, Mary Beth, Chenevix-Trench, Georgia, Antoniou, Antonis C, Ottini, Laura, Nussbaum, Robert L, Olopade, Olufunmilayo I, Rantala, Johanna, Arason, Adalgeir, Yoon, Sook-Yee, Caligo, Maria A, Spugnesi, Laura, Bojesen, Anders, Pedersen, Inge Sokilde, Thomassen, Mads, Jensen, Uffe Birk, Toland, Amanda Ewart, Senter, Leigha, Andrulis, Irene L, Johannsson, Oskar Th, Glendon, Gord, Hulick, Peter J, Imyanitov, Evgeny N, Greene, Mark H, Mai, Phuong L, Singer, Christian F, Rappaport-Fuerhauser, Christine, Kramer, Gero, Vijai, Joseph, Offit, Kenneth, Barkardottir, Rosa B, Robson, Mark, Lincoln, Anne, Jacobs, Lauren, Machackova, Eva, Foretova, Lenka, Navratilova, Marie, Vasickova, Petra, Couch, Fergus J, Hallberg, Emily, Ruddy, Kathryn J, Jakubowska, Anna, Sharma, Priyanka, Kim, Sung-Won, Teixeira, Manuel R, Pinto, Pedro, Montagna, Marco, Matricardi, Laura, Lubinski, Jan, Izquierdo, Angel, Pujana, Miguel Angel, Balmaña, Judith, Diez, Orland, Ivady, Gabriella, Hamann, Ute, Papp, Janos, Olah, Edith, Kwong, Ava, Nevanlinna, Heli, Aittomäki, Kristiina, Perez Segura, Pedro, Caldes, Trinidad, Van Maerken, Tom, Poppe, Bruce, Claes, Kathleen B M, Garber, Judy, Isaacs, Claudine, Elan, Camille, Lasset, Christine, Stoppa-Lyonnet, Dominique, Barjhoux, Laure, Belotti, Muriel, Meindl, Alfons, Gehrig, Andrea, Sutter, Christian, Engel, Christoph, Fostira, Florentia, Niederacher, Dieter, Steinemann, Doris, Hahnen, Eric, Kast, Karin, Arnold, Norbert, Varon-Mateeva, Raymonda, Wand, Dorothea, Godwin, Andrew K, Evans, D Gareth, Frost, Debra

المساهمون: 1 Univ Roma La Sapienza, Dept Mol Med, Viale Regina Elena 324, I-00161 Rome, Italy 2 Univ Cambridge, Sch Clin Med, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England 3 Univ Hlth Network, Lab Med Program, Toronto, ON, Canada 4 Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada 5 City Hope Natl Med Ctr, Beckman Res Inst, Dept Populat Sci, Duarte, CA 91010 USA 6 Peter MacCallum Canc Inst, East Melbourne, Australia 7 Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Womens Canc Program, Los Angeles, CA 90048 USA 8 Peter MacCallum Canc Ctr, Familial Canc Ctr, Melbourne, Vic, Australia 9 Univ Melbourne, Dept Oncol, Melbourne, Vic, Australia 10 Univ Pittsburgh, Sch Med, Pittsburgh, PA USA 11 UPMC Canc Ctr, Pittsburgh, PA USA 12 Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Dept Med, Philadelphia, PA 19104 USA 13 Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Dept Epidemiol & Biostat, Philadelphia, PA 19104 USA 14 Univ So Calif, Keck Sch Med, Norris Comprehens Canc Ctr, Dept Prevent Med, Los Angeles, CA 90033 USA 15 Univ Calif San Francisco, Dept Med & Genet, San Francisco, CA 94143 USA 16 Univ Chicago, Med Ctr, Ctr Clin Canc Genet & Global Hlth, Chicago, IL 60637 USA 17 Karolinska Univ Hosp, Dept Clin Genet, Stockholm, Sweden 18 Sime Darby Med Ctr, Canc Res Initiat Fdn, Subang Jaya, Malaysia 19 Univ Malaya, Med Ctr, Fac Med, Canc Res Inst, Kuala Lumpur, Malaysia 20 Univ Pisa, Dept Lab Med, Sect Genet Oncol, Pisa, Italy 21 Univ Hosp Pisa, Pisa, Italy 22 Vejle Hosp, Dept Clin Genet, Vejle, Denmark 23 Aalborg Univ Hosp, Dept Biochem, Sect Mol Diagnost, Aalborg, Denmark 24 Odense Univ Hosp, Dept Clin Genet, DK-5000 Odense C, Denmark 25 Aarhus Univ Hosp, Dept Clin Genet, DK-8000 Aarhus N, Denmark 26 Ohio State Univ, Coll Med, Dept Mol Virol Immunol & Med Genet, Columbus, OH 43210 USA 27 Ohio State Univ, Dept Internal Med, Ctr Comprehens Canc, Dept Human Genet, Columbus, OH 43210 USA 28 Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON M5G 1X5, Canada 29 Univ Toronto, Dept Mol Genet, Toronto, ON, Canada 30 North Shore Univ Hlth Syst, Ctr Med Genet, Evanston, IL USA 31 NN Petrov Oncol Res Inst, St Petersburg, Russia 32 NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, NIH, Rockville, MD USA 33 Med Univ Vienna, Ctr Comprehens Canc, Dept Obstet & Gynecol, Vienna, Austria 34 Med Univ Vienna, Dept Urol, Vienna, Austria 35 Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA 36 Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA 37 Masaryk Mem Canc Inst, Dept Canc Epidemiol & Genet, Brno, Czech Republic 38 Masaryk Univ, Masaryk Mem Canc Inst, Brno, Czech Republic 39 Masaryk Univ, Fac Med, Brno, Czech Republic 40 Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA 41 Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA 42 Mayo Clin, Dept Oncol, Rochester, MN USA 43 Univ Kansas, Med Ctr, Dept Hematol & Oncol, Kansas City, KS 66103 USA 44 Daerim St Marys Hosp, Dept Surg, Seoul, South Korea 45 Portuguese Inst Oncol, Dept Genet, Oporto, Portugal 46 Univ Porto, Biomed Sci Inst ICBAS, Rua Campo Alegre 823, P-4100 Oporto, Portugal 47 IRCCS Sci Inst Hospitalizat & Care, IOV, Immunol & Mol Oncol Unit, Padua, Italy 48 Landspitali Univ Hosp, Dept Pathol, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 49 Univ Iceland, Fac Med, Biomed Ctr BMC, Reykjavik, Iceland 50 Landspitali Univ Hosp, Dept Oncol, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 51 Univ Iceland, Fac Med, Reykjavik, Iceland 52 Pomeranian Med Univ, Dept Genet & Pathol, Szczecin, Poland 53 Catalan Inst Oncol, Biomed Res Inst Girona IDIBGI, Hereditary Canc Program, Genet Counseling Unit, Girona, Spain 54 Catalan Inst Oncol, Bellvitge Biomed Res Inst IDIBELL, Breast Canc & Syst Biol Unit, Barcelona, Spain 55 Vall dHebron Univ Hosp, Dept Med Oncol, Barcelona, Spain 56 Vall dHebron Univ Hosp, Oncogenet Grp, VHIO, Barcelona, Spain 57 Univ Autonoma Barcelona, E-08193 Barcelona, Spain 58 Natl Inst Oncol, Dept Pathol, Budapest, Hungary 59 Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary 60 Hong Kong Sanat & Hosp, Canc Genet Ctr, Hong Kong Hereditary Breast Canc Family Registry, Hong Kong, Hong Kong, Peoples R China 61 Univ Hong Kong, Dept Surg, Hong Kong, Hong Kong, Peoples R China 62 Univ Helsinki, Dept Obstet & Gynecol, Helsinki, Finland 63 Helsinki Univ Hosp, Helsinki, Finland 64 Univ Helsinki, Dept Clin Genet, Helsinki, Finland 65 San Carlos Clin Hosp, Hlth Res Inst IdISSC, Dept Oncol, Madrid, Spain 66 San Carlos Clin Hosp, Hlth Res Inst IdISSC, Mol Oncol Lab, Madrid, Spain 67 Univ Ghent, Ctr Med Genet, B-9000 Ghent, Belgium 68 Georgetown Univ, Lombardi Comprehens Canc Ctr, Washington, DC USA 69 Inst Curie, Dept Tumor Biol, Paris, France 70 Univ Lyon 1, CNRS UMR5558, F-69365 Lyon, France 71 Ctr Leon Berard, Unite Prevent & Epidemiol Genet, F-69373 Lyon, France 72 Univ Paris 05, Sorbonne Paris Cite, Paris, France 73 Univ Lyon, Ctr Rech Cancerol Lyon, CNRS UMR5286, INSERM U1052, Lyon, France 74 Tech Univ Munich, Dept Obstet & Gynaecol, D-80290 Munich, Germany 75 Univ Wurzburg, Inst Human Genet, Wurzburg, Germany 76 Univ Heidelberg Hosp, Inst Human Genet, Heidelberg, Germany 77 Univ Leipzig, Inst Med Informat Stat & Epidemiol, D-04109 Leipzig, Germany 78 Univ Dusseldorf, Dusseldorf, Germany 79 Hannover Med Sch, Hannover, Germany 80 Univ Cologne, Fac Med, Ctr Hereditary Breast & Ovarian Canc, D-50931 Cologne, Germany 81 Univ Cologne, Fac Med, CIO, D-50931 Cologne, Germany 82 Univ Cologne, Fac Med, CMMC, D-50931 Cologne, Germany 83 Univ Hosp Cologne, Cologne, Germany 84 Tech Univ Dresden, Dept Obstet & Gynecol, D-01062 Dresden, Germany 85 Univ Kiel, Univ Hosp Schleswig Holstein, Dept Gynaecolgy & Obstet, Kiel, Germany 86 Charite, Inst Human Genet, Berlin, Germany 87 Univ Kansas, Med Ctr, Dept Pathol & Lab Med, Kansas City, KS 66103 USA 88 Cent Manchester Univ Hosp NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Genet Med, Manchester, Lancs, England 89 Yorkshire Reg Genet Serv, Leeds, W Yorkshire, England 90 Guys & St Thomas NHS Fdn Trust, Clin Genet, London, England 91 Inst Canc Res, Oncogenet Team, Sutton, Surrey, England 92 Royal Marsden NHS Fdn Trust, Sutton, Surrey, England 93 German Canc Res Ctr, Mol Genet Breast Canc, Heidelberg, Germany 94 Dana Farber Canc Inst, Canc Risk & Prevent Clin, Boston, MA 02115 USA 95 Natl Ctr Sci Res Demokritos, Inst Nucl & Radiol Sci & Technol INRASTES, Mol Diagnost Lab, Athens, Greece 96 Aristotle Univ Thessaloniki, Dept Med Oncol, Papageorgiou Hosp, Sch Med, GR-54006 Thessaloniki, Greece 97 Univ Turin, Dept Med Sci, Turin, Italy 98 AO Citta Salute & Sci, Turin, Italy 99 Univ Palermo, Dept Surg & Ontol Sci, Sect Med Oncol, Palermo, Italy 100 Univ Modena & Reggio Emilia, Dept Haematol & Oncol, Modena, Italy 101 Univ Florence, Dept Biomed Expt & Clin Sci, Unit Med Genet, Florence, Italy 102 Natl Inst Canc Res, AOU San Martino IST, IRCCS Sci Inst Hospitalizat & Care, Unit Hereditary Canc,Dept Epidemiol Prevent & Spe, Genoa, Italy 103 Canc Res & Prevent Inst ISPO, Mol & Nutr Epidemiol Unit, Florence, Italy 104 Regina Elena Inst Canc Res, Dept Med Oncol, Unit Genet Counselling, Rome, Italy 105 Natl Canc Inst INT, IRCCS Sci Inst Hospitalizat & Care, Unit Mol Bases Genet Risk & Genet Testing, Dept Prevent & Predict Med, I-20133 Milan, Italy 106 Natl Canc Inst INT, IRCCS Sci Inst Hospitalizat & Care, Dept Prevent & Predict Med, Unit Med Genet, I-20133 Milan, Italy 107 European Inst Oncol, Div Canc Prevent & Genet, Milan, Italy 108 CRO Avian Natl Canc Inst, Div Expt Oncol, Avian, PN, Italy 109 FIRC, IFOM, Inst Mol Oncol, Milan, Italy 110 Cogentech Canc Genet Test Lab, Milan, Italy 111 Natl Canc Inst Giovanni Paolo II, Bari, Italy 112 City Hope Clin Canc Genet Community Res Network, Clin Canc Genet, Duarte, CA USA 113 Spanish Natl Canc Ctr CNIO, Human Genet Grp, Human Canc Genet Program, Madrid, Spain 114 Biomed Network Rare Dis CIBERER, Madrid, Spain 115 Spanish Natl Canc Ctr CNIO, Human Genet Grp, Madrid, Spain 116 Spanish Natl Canc Res Ctr CNIO, Human Canc Genet Program, Human Genotyping CEGEN Unit, Madrid, Spain 117 QIMR Berghofer Med Res Inst, Canc Div, Brisbane, Qld, Australia 118 Copenhagen Univ Hosp, Rigshosp, Dept Clin Genet, Copenhagen, Denmark 119 Copenhagen Univ Hosp, Rigshosp, Dept Oncol, Copenhagen, Denmark 120 Copenhagen Univ Hosp, Rigshosp, Ctr Genom Med, Copenhagen, Denmark 121 Beth Israel Deaconess Med Ctr, Dept Med Oncol, Boston, MA 02215 USA 122 State Res Inst, Ctr Innovat Med, Vilnius, Lithuania 123 Univ Utah, Sch Med, Huntsman Canc Inst, Dept Dermatol, Salt Lake City, UT USA 124 Univ Utah, Sch Med, Dept Med, Huntsman Canc Inst, Salt Lake City, UT USA 125 Fox Chase Canc Ctr, Dept Clin Genet, 7701 Burholme Ave, Philadelphia, PA 19111 USA 126 McMaster Univ, Dept Pathol & Mol Med, Juravinski Hosp & Canc Ctr, Hamilton, ON, Canada 127 Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA 128 Canc Prevent Inst Calif, Dept Epidemiol, Fremont, CA USA 129 Univ Melbourne, Dept Pathol, Genet Epidemiol Lab, Parkville, Vic 3052, Australia

مصطلحات موضوعية: Brjóstakrabbamein, Karlar, Arfgengi, MAO12, NAF12, Breast Neoplasms, Male, DNA Mutational Analysis, Genes, BRCA1, BRCA2, Genetic Predisposition to Disease

العلاقة: http://dx.doi.orgTest/ 10.1186/s13058-016-0671-y; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746828Test/; Breast Cancer Res. 2016, 18 (1):15; http://hdl.handle.net/2336/607209Test; Breast cancer research : BCR

الإتاحة: https://doi.org/10.1186/s13058-016-0671-yTest
http://hdl.handle.net/2336/607209Test

المؤلفون: Patel, Vivek L, Busch, Evan L, Friebel, Tara M, Cronin, Angel, Leslie, Goska, McGuffog, Lesley, Adlard, Julian, Agata, Simona, Agnarsson, Bjarni A, Ahmed, Munaza, Aittomäki, Kristiina, Alducci, Elisa, Andrulis, Irene L, Arason, Adalgeir, Arnold, Norbert, Artioli, Grazia, Arver, Brita, Auber, Bernd, Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B, Barnes, Daniel R, Barroso, Alicia, Barrowdale, Daniel, Belotti, Muriel, Benitez, Javier, Bertelsen, Brigitte, Blok, Marinus J, Bodrogi, Istvan, Bonadona, Valérie, Bonanni, Bernardo, Bondavalli, Davide, Boonen, Susanne E, Borde, Julika, Borg, Ake, Bradbury, Angela R, Brady, Angela, Brewer, Carole, Brunet, Joan, Buecher, Bruno, Buys, Saundra S, Cabezas-Camarero, Santiago, Caldés, Trinidad, Caliebe, Almuth, Caligo, Maria A, Calvello, Mariarosaria, Campbell, Ian G, Carnevali, Ileana, Carrasco, Estela, Chan, Tsun L, Chu, Annie T W, Chung, Wendy K, Claes, Kathleen B M, Collaborators, Gemo Study, Collaborators, Embrace, Cook, Jackie, Cortesi, Laura, Couch, Fergus J, Daly, Mary B, Damante, Giuseppe, Darder, Esther, Davidson, Rosemarie, de la Hoya, Miguel, Puppa, Lara Della, Dennis, Joe, Díez, Orland, Ding, Yuan Chun, Ditsch, Nina, Domchek, Susan M, Donaldson, Alan, Dworniczak, Bernd, Easton, Douglas F, Eccles, Diana M, Eeles, Rosalind A, Ehrencrona, Hans, Ejlertsen, Bent, Engel, Christoph, Evans, D Gareth, Faivre, Laurence, Faust, Ulrike, Feliubadaló, Lídia, Foretova, Lenka, Fostira, Florentia, Fountzilas, George, Frost, Debra, García-Barberán, Vanesa, Garre, Pilar, Gauthier-Villars, Marion, Géczi, Lajos, Gehrig, Andrea, Gerdes, Anne-Marie, Gesta, Paul, Giannini, Giuseppe, Glendon, Gord, Godwin, Andrew K, Goldgar, David E, Greene, Mark H, Gutierrez-Barrera, Angelica M, Hahnen, Eric, Hamann, Ute, Hauke, Jan, Herold, Natalie, Hogervorst, Frans B L, Honisch, Ellen, Hopper, John L, Hulick, Peter J, Investigators, KConFab, Investigators, Hebon, Izatt, Louise, Jager, Agnes, James, Paul, Janavicius, Ramunas, Jensen, Uffe Birk, Jensen, Thomas Dyrso, Johannsson, Oskar Th, John, Esther M, Joseph, Vijai, Kang, Eunyoung, Kast, Karin, Kiiski, Johanna I, Kim, Sung-Won, Kim, Zisun, Ko, Kwang-Pil, Konstantopoulou, Irene, Kramer, Gero, Krogh, Lotte, Kruse, Torben A, Kwong, Ava, Larsen, Mirjam, Lasset, Christine, Lautrup, Charlotte, Lazaro, Conxi, Lee, Jihyoun, Lee, Jong Won, Lee, Min Hyuk, Lemke, Johannes, Lesueur, Fabienne, Liljegren, Annelie, Lindblom, Annika, Llovet, Patricia, Lopez-Fernández, Adria, Lopez-Perolio, Irene, Lorca, Victor, Loud, Jennifer T, Ma, Edmond S K, Mai, Phuong L, Manoukian, Siranoush, Mari, Veronique, Martin, Lynn, Matricardi, Laura, Mebirouk, Noura, Medici, Veronica, Meijers-Heijboer, Hanne E J, Meindl, Alfons, Mensenkamp, Arjen R, Miller, Clare, Gomes, Denise Molina, Montagna, Marco, Mooij, Thea M, Moserle, Lidia, Mouret-Fourme, Emmanuelle, Mulligan, Anna Marie, Nathanson, Katherine L, Navratilova, Marie, Nevanlinna, Heli, Niederacher, Dieter, Nielsen, Finn C Cilius, Nikitina-Zake, Liene, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Ong, Kai-Ren, Osorio, Ana, Ott, Claus-Eric, Palli, Domenico, Park, Sue K, Parsons, Michael T, Pedersen, Inge Sokilde, Peissel, Bernard, Peixoto, Ana, Pérez-Segura, Pedro, Peterlongo, Paolo, Petersen, Annabeth Høgh, Porteous, Mary E, Pujana, Miguel Angel, Radice, Paolo, Ramser, Juliane, Rantala, Johanna, Rashid, Muhammad U, Rhiem, Kerstin, Rizzolo, Piera, Robson, Mark E, Rookus, Matti A, Rossing, Caroline M, Ruddy, Kathryn J, Santos, Catarina, Saule, Claire, Scarpitta, Rosa, Schmutzler, Rita K, Schuster, Hélène, Senter, Leigha, Seynaeve, Caroline M, Shah, Payal D, Sharma, Priyanka, Shin, Vivian Y, Silvestri, Valentina, Simard, Jacques, Singer, Christian F, Skytte, Anne-Bine, Snape, Katie, Solano, Angela R, Soucy, Penny, Southey, Melissa C, Spurdle, Amanda B, Steele, Linda, Steinemann, Doris, Stoppa-Lyonnet, Dominique, Stradella, Agostina, Sunde, Lone, Sutter, Christian, Tan, Yen Y, Teixeira, Manuel R, Teo, Soo Hwang, Thomassen, Mads, Tibiletti, Maria Grazia, Tischkowitz, Marc, Tognazzo, Silvia, Toland, Amanda E, Tommasi, Stefania, Torres, Diana, Toss, Angela, Trainer, Alison H, Tung, Nadine, van Asperen, Christi J, van der Baan, Frederieke H, van der Kolk, Lizet E, van der Luijt, Rob B, van Hest, Liselotte P, Varesco, Liliana, Varon-Mateeva, Raymonda, Viel, Alessandra, Vierstraete, Jeroen, Villa, Roberta, von Wachenfeldt, Anna, Wagner, Philipp, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Weitzel, Jeffrey N, Wieme, Greet, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yoon, Sook-Yee, Zanzottera, Cristina, Zorn, Kristin K, D'Amico, Anthony V, Freedman, Matthew L, Pomerantz, Mark M, Chenevix-Trench, Georgia, Antoniou, Antonis C, Neuhausen, Susan L, Ottini, Laura, Nielsen, Henriette Roed, Rebbeck, Timothy R

المساهمون: 1Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts. 2Harvard T.H. Chan School of Public Health, Boston, Massachusetts. 3Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. 4Dana-Farber Cancer Institute. Boston, Massachusetts. 5Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. 6Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, United Kingdom. 7Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. 8Department of Pathology, Landspitali University Hospital, 101, Reykjavik, Iceland. 9School of Medicine, University of Iceland, Reykjavik, Iceland. 10North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom. 11Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. 12Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada. 13Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. 14BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 15Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany. 16ULSS 3 Serenissima, U.O.C. Oncologia ed Ematologia Oncologica, Mirano, Venice, Italy. 17Department of Oncology, Karolinska Institutet, Stockholm, Sweden. 18Institute of Human Genetics, Hannover Medical School, Hannover, Germany. 19Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori di Milano, Milan, Italy. 20High Risk and Cancer Prevention Group, Vall d'Hebron Institute of Oncology, University Hospital Vall d'Hebron, Barcelona, Spain. 21Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. 22Service de Génétique, Institut Curie, Paris, France. 23Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. 24Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. 25Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 26Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands. 27Department of Chemotherapy, National Institute of Oncology, Budapest, Hungary. 28Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France. 29Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, Milan, Italy. 30Clinical Genetic Unit, Department of Paediatrics, Zealand University Hospital, Roskilde, Denmark. 31Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany. 32Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. 33Center for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany. 34Department of Oncology, Lund University and Skåne University Hospital, Lund, Sweden. 35Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. 36North West Thames Regional Genetics Service, Kennedy Galton Centre, The North West London Hospitals NHS Trust, Middlesex, United Kingdom. 37Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom. 38Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, CIBERONC, Girona, Spain. 39Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah. 40Department of Oncology, Hospital Clinico San Carlos, IdISSC, Madrid, Spain. 41Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. 42Institute of Human Genetics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany. 43Section of Molecular Genetics, Department of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy. 44Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. 45Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia. 46UO Anatomia Patologica, Ospedale di Circolo-Università dell'Insubria, Varese, Italy. 47Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Centre, Happy Valley, Hong Kong. 48Department of Pathology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong. 49Departments of Pediatrics and Medicine, Columbia University, New York, New York. 50Centre for Medical Genetics, Ghent University, Ghent, Belgium. 51Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom. 52Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy. 53Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota. 54Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania. 55Department of Medical and Biological Sciences, University of Udine, Udine, Italy. 56Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, United Kingdom. 57Division of Functional Onco-genomics and Genetics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy. 58Oncogenetics Group, Clinical and Molecular Genetics Area, Vall d'Hebron Institute of Oncology (VHIO), University Hospital, Barcelona, Spain. 59Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California. 60Department of Gynecology and Obstetrics, Ludwig Maximilian University of Munich, Munich, Germany. 61Clinical Genetics Department, St Michael's Hospital, Bristol, United Kingdom. 62Institute of Human Genetics, University of Münster, Münster, Germany. 63Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom. 64Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom. 65Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, United Kingdom. 66Department of Clinical Genetics, Lund University Hospital, Lund, Sweden. 67Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 68Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. 69LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany. 70Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health and Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom. 71Manchester Centre for Genomic Medicine, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust and Manchester Academic Health Science Centre, Manchester, United Kingdom. 72Unité d'oncogénétique, Centre de Lutte Contre le Cancer, Centre Georges-François Leclerc, Dijon, France. 73Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany. 74Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 75Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. 76Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Athens, Greece. 77Second Department of Medical Oncology, EUROMEDICA General Clinic of Thessaloniki, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece. 78Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University of Würzburg, Würzburg, Germany. 79Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark. 80Service Régional Oncogénétique Poitou-Charentes, CH Niort, Niort, France. 81Department of Molecular Medicine, University La Sapienza, Rome, Italy. 82Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kansas. 83Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah. 84Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland. 85Department of Breast Medical Oncology and Clinical Genetics Program, University of Texas MD Anderson Cancer Center, Houston, Texas. 86Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. 87Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands. 88Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany. 89Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia. 90Center for Medical Genetics, NorthShore University HealthSystem, Evanston, Illinois. 91The University of Chicago Pritzker School of Medicine, Chicago, Illinois. 92The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), Coordinating center: The Netherlands Cancer Institute, Amsterdam, the Netherlands. 93Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom. 94Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands. 95Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. 96Hematology, Oncology and Transfusion Medicine Center, Department of Molecular and Regenerative Medicine, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania. 97Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark. 98Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. 99Department of Oncology, Landspitali University Hospital, Reykjavik, Iceland. 100Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California. 101Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York. 102Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea. 103Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden, Germany. 104Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. 105Department of Surgery, Daerim Saint Mary's Hospital, Seoul, Korea. 106Department of Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. 107Department of Preventive Medicine, Gacheon University College of Medicine, Incheon, Republic of Korea. 108Department of Urology, Medical University of Vienna, Vienna, Austria. 109Department of Clinical Genetics, Odense University Hospital, Odense, Denmark. 110Department of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong. 111Department of Surgery, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong. 112Department of Clinical Genetics, Aalborg University Hospital, Aalborg, Denmark. 113Department of Surgery, Soonchunhyang University College of Medicine and Soonchunhyang University Hospital, Seoul, Korea. 114Department of Surgery, Ulsan University College of Medicine and Asan Medical Center, Seoul, Korea. 115Institute of Human Genetics, University Hospital Leipzig, Leipzig, Germany. 116Genetic Epidemiology of Cancer Team, Inserm U900, Paris, France. 117Institut Curie, Paris, France. 118Mines ParisTech, Fontainebleau, France. 119Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. 120Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden. 121Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. 122Département d'Hématologie-Oncologie Médicale, Centre Antoine Lacassagne, Nice, France. 123Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom. 124Department of Clinical Genetics, VU University Medical Center, Amsterdam, the Netherlands. 125Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands. 126Department of Clinical Genetics, Alder Hey Hospital, Liverpool, United Kingdom. 127Service de Biologie de la Reproduction, Cytogénétique et Génétique Médicale, CHI Poissy - Saint Germain, Poissy, France. 128Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. 129Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. 130Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada. 131Latvian Biomedical Research and Study Centre, Riga, Latvia. 132Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York. 133Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. 134Center for Clinical Cancer Genetics, The University of Chicago, Chicago, Illinois. 135West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Birmingham, United Kingdom. 136Institute for Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. 137Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy. 138Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea. 139Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea. 140Cancer Research Institute, Seoul National University, Seoul, Korea. 141Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. 142Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark. 143Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. 144Genome Diagnostics Program, IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. 145South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom. 146Translational Research Laboratory, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 147Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, in Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. 148Division of Gynaecology and Obstetrics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany. 149Clinical Genetics, Karolinska Institutet, Stockholm, Sweden. 150Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan. 151Department of Oncology, Mayo Clinic, Rochester, Minnesota. 152Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa, Italy. 153Unité d'Oncogénétique, Centre de Lutte Contre le Cancer Paul Strauss, Strasbourg, France. 154Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio. 155Department of Internal Medicine, Division of Oncology, University of Kansas Medical Center, Westwood, Kansas. 156Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval, Research Centre, Québec City, Québec, Canada. 157Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. 158Medical Genetics Unit, St George's, University of London, London, United Kingdom. 159INBIOMED, Faculty of Medicine/CONICET and CEMIC, Department of Clinical Chemistry, Medical Direction, University of Buenos Aires, Buenos Aires, Argentina. 160Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia. 161Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia. 162Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany. 163Department of Tumour Biology, INSERM U830, Paris, France. 164Université Paris Descartes, Paris, France. 165Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain. 166Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. 167Department of OB/GYN, Medical University of Vienna, Vienna, Austria. 168Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal. 169Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia. 170Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia. 171Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Quebec, Canada. 172Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom. 173Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio. 174Istituto Nazionale Tumori 'Giovanni Paolo II, Bari, Italy. 175Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia. 176Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts. 177Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. 178Department of Medical Genetics, University Medical Center, Utrecht, the Netherlands. 179Clinical Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. 180Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) AOU San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy. 181Department of Women's Health, Tubingen University Hospital, Tubingen, Germany. 182Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany. 183Clinical Cancer Genetics, City of Hope, Duarte, California. 184Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Selangor, Malaysia. 185Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Timothy_Rebbeck@dfci.harvard.edu.

المصدر: Cancer research ; 80 ; 3 ; 624 ; 638 ; United Kingdom ; United States ; Canada

مصطلحات موضوعية: Blöðruhálskirtilskrabbamein, Gen, Genes, BRCA1, BRCA2, Prostatic Neoplasms, Genetic Association Studies

العلاقة: https://cancerres.aacrjournals.org/content/80/3/624.longTest; Patel VL, Busch EL, Friebel TM, et al. Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Cancer Res. 2020;80(3):624-638. doi:10.1158/0008-5472.CAN-19-1840; http://hdl.handle.net/2336/621479Test; Cancer research

الإتاحة: https://doi.org/10.1158/0008-5472.CAN-19-1840Test
http://hdl.handle.net/2336/621479Test

المؤلفون: Lecarpentier, Julie, Silvestri, Valentina, Kuchenbaecker, Karoline B, Barrowdale, Daniel, Dennis, Joe, McGuffog, Lesley, Soucy, Penny, Leslie, Goska, Rizzolo, Piera, Navazio, Anna Sara, Valentini, Virginia, Gutiérrez-Enríquez, Sara, Diez, Orland, Teulé, Alex, Izquierdo, Angel, Darder, Esther, Brunet, Joan, Del Valle, Jesús, Feliubadalo, Lidia, Pujana, Miquel Angel, Lazaro, Conxi, Zelli, Veronica, Arason, Adalgeir, Agnarsson, Bjarni A, Johannsson, Oskar Th, Barkardottir, Rosa B, Alducci, Elisa, Tognazzo, Silvia, Montagna, Marco, Teixeira, Manuel R, Pinto, Pedro, Spurdle, Amanda B, Lee, Andrew, Holland, Helene, Lee, Jong Won, Lee, Min Hyuk, Lee, Jihyoun, Kim, Sung-Won, Kang, Eunyoung, Kim, Zisun, Sharma, Priyanka, Rebbeck, Timothy R, Vijai, Joseph, Amin Al Olama, Ali, Robson, Mark, Lincoln, Anne, Musinsky, Jacob, Gaddam, Pragna, Tan, Yen Y, Berger, Andreas, Singer, Christian F, Loud, Jennifer T, Greene, Mark H, Mulligan, Anna Marie, Tyrer, Jonathan P, Glendon, Gord, Andrulis, Irene L, Toland, Amanda Ewart, Senter, Leigha, Bojesen, Anders, Nielsen, Henriette Roed, Skytte, Anne-Bine, Sunde, Lone, Jensen, Uffe Birk, Pedersen, Inge Sokilde, Southey, Melissa, Krogh, Lotte, Kruse, Torben A, Caligo, Maria A, Yoon, Sook-Yee, Teo, Soo-Hwang, von Wachenfeldt, Anna, Huo, Dezheng, Nielsen, Sarah M, Olopade, Olufunmilayo I, Nathanson, Katherine L, John, Esther M, Domchek, Susan M, Lorenchick, Christa, Jankowitz, Rachel C, Campbell, Ian, James, Paul, Mitchell, Gillian, Orr, Nick, Park, Sue Kyung, Thomassen, Mads, Offit, Kenneth, Conner, Thomas A, Couch, Fergus J, Simard, Jacques, Easton, Douglas F, Chenevix-Trench, Georgia, Schmutzler, Rita K, Antoniou, Antonis C, Ottini, Laura, Goldgar, David E, Buys, Saundra S, Janavicius, Ramunas, Steele, Linda, Ding, Yuan Chun, Neuhausen, Susan L, Hansen, Thomas V O, Osorio, Ana, Weitzel, Jeffrey N, Toss, Angela, Medici, Veronica, Cortesi, Laura, Zanna, Ines, Palli, Domenico, Radice, Paolo, Manoukian, Siranoush, Peissel, Bernard, Azzollini, Jacopo, Viel, Alessandra, Cini, Giulia, Damante, Giuseppe, Tommasi, Stefania, Peterlongo, Paolo, Fostira, Florentia, Hamann, Ute, Evans, D Gareth, Henderson, Alex, Brewer, Carole, Eccles, Diana, Cook, Jackie, Ong, Kai-Ren, Walker, Lisa, Side, Lucy E, Porteous, Mary E, Davidson, Rosemarie, Hodgson, Shirley, Frost, Debra, Adlard, Julian, Izatt, Louise, Eeles, Ros, Ellis, Steve, Tischkowitz, Marc, Godwin, Andrew K, Meindl, Alfons, Gehrig, Andrea, Dworniczak, Bernd, Sutter, Christian, Engel, Christoph, Niederacher, Dieter, Steinemann, Doris, Hahnen, Eric, Hauke, Jan, Rhiem, Kerstin, Kast, Karin, Arnold, Norbert, Ditsch, Nina, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Wand, Dorothea, Lasset, Christine, Stoppa-Lyonnet, Dominique, Belotti, Muriel, Damiola, Francesca, Barjhoux, Laure, Mazoyer, Sylvie, Van Heetvelde, Mattias, Poppe, Bruce, De Leeneer, Kim, Claes, Kathleen B M, de la Hoya, Miguel, Garcia-Barberan, Vanesa, Caldes, Trinidad, Perez Segura, Pedro, Kiiski, Johanna I, Aittomäki, Kristiina, Khan, Sofia, Nevanlinna, Heli, van Asperen, Christi J, Vaszko, Tibor, Kasler, Miklos, Olah, Edith, Balmaña, Judith

المساهمون: 1 Univ Cambridge, Cambridge, England Show the Organization-Enhanced name(s) 2 Wellcome Trust Sanger Inst, Hinxton, England Show the Organization-Enhanced name(s) 3 Addenbrookes Hosp, Addenbrookes Treatment Ctr, Cambridge, England Show the Organization-Enhanced name(s) 4 Univ Manchester, Cent Manchester Univ Hosp NHS Fdn Trust, Manchester, Lancs, England 5 Newcastle Tyne Hosp NHS Trust, Newcastle Upon Tyne, Tyne & Wear, England Show the Organization-Enhanced name(s) 6 Royal Devon & Exeter Hosp, Exeter, Devon, England Show the Organization-Enhanced name(s) 7 Southampton Univ Hosp NHS Trust, Southampton, Hants, England 8 Sheffield Childrens Hosp, Sheffield, S Yorkshire, England 9 Birmingham Womens Hosp Healthcare NHS Trust, Birmingham, W Midlands, England Show the Organization-Enhanced name(s) 10 Churchill Hosp, Oxford, England Show the Organization-Enhanced name(s) 11 Great Ormond St Hosp Sick Children, London, England Show the Organization-Enhanced name(s) 12 St Georges Univ London, London, England Show the Organization-Enhanced name(s) 13 Guys & St Thomas NHS Fdn Trust, London, England Show the Organization-Enhanced name(s) 14 Inst Canc Res, London, England Show the Organization-Enhanced name(s) 15 Royal Marsden NHS Fdn Trust, London, England Show the Organization-Enhanced name(s) 16 Western Gen Hosp, Edinburgh, Midlothian, Scotland 17 South Glasgow Univ Hosp, Glasgow, Lanark, Scotland 18 Chapel Allerton Hosp, Leeds, W Yorkshire, England Show the Organization-Enhanced name(s) 19 Sapienza Univ Rome, Rome, Italy Show the Organization-Enhanced name(s) 20 Univ Modena & Reggio Emilia, Modena, Italy 21 Canc Res & Prevent Inst, Florence, Italy 22 Fdn Ist Ricovero & Cura Carattere Sci, INT, Milan, Italy 23 Italian Fdn Canc Res, Inst Mol Oncol IFOM, Milan, Italy Show the Organization-Enhanced name(s) 24 Natl Canc Inst, CRO Aviano, Aviano, Italy Show the Organization-Enhanced name(s) 25 Univ Udine, Udine, Italy 26 Ist Nazl Tumori Giovanni Paolo II, Bari, Italy Show the Organization-Enhanced name(s) 27 Veneto Inst Oncol IOV IRCCS, Padua, Italy Show the Organization-Enhanced name(s) 28 Univ Pisa, Pisa, Italy 29 Univ Hosp Pisa, Pisa, Italy 30 Ctr Hosp Univ Quebec Res Ctr, Quebec City, PQ, Canada Show the Organization-Enhanced name(s) 31 Laval Univ, Quebec City, PQ, Canada Show the Organization-Enhanced name(s) 32 Univ Toronto, Toronto, ON, Canada Show the Organization-Enhanced name(s) 33 Mt Sinai Hosp, Toronto, ON, Canada Show the Organization-Enhanced name(s) 34 Univ Melbourne, Parkville, Vic, Australia Show the Organization-Enhanced name(s) 35 QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia Show the Organization-Enhanced name(s) 36 Peter MacCallum Canc Ctr, East Melbourne, NSW, Australia Show the Organization-Enhanced name(s) 37 Canc Prevent Inst Calif, Fremont, CA USA Show the Organization-Enhanced name(s) 38 City Hope Natl Med Ctr, Duarte, CA USA 39 Huntsman Canc Inst, Salt Lake City, UT USA Show the Organization-Enhanced name(s) 40 Univ Utah, Sch Med, Salt Lake City, UT USA Show the Organization-Enhanced name(s) 41 Univ Kansas, Med Ctr, Kansas City, KS 66103 USA Show the Organization-Enhanced name(s) 42 Univ Kansas, Med Ctr, Westwood, KS USA 43 Harvard TH Chan Sch Publ Hlth, Boston, MA USA Show the Organization-Enhanced name(s) 44 Dana Farber Canc Inst, Boston, MA 02115 USA Show the Organization-Enhanced name(s) 45 Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Show the Organization-Enhanced name(s) 46 NCI, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 47 Ohio State Univ, Columbus, OH 43210 USA Show the Organization-Enhanced name(s) 48 Univ Chicago, Med Ctr, Chicago, IL 60637 USA Show the Organization-Enhanced name(s) 49 Univ Penn, Philadelphia, PA 19104 USA Show the Organization-Enhanced name(s) 50 Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA Show the Organization-Enhanced name(s) 51 Mayo Clin, Rochester, MN USA Show the Organization-Enhanced name(s) 52 State Res Inst Innovat Med Ctr, Vilnius, Lithuania Show the Organization-Enhanced name(s) 53 Copenhagen Univ Hosp, Rigshosp, Copenhagen, Denmark 54 Vejle Hosp, Vejle, Denmark Show the Organization-Enhanced name(s) 55 Aarhus Univ Hosp, Aarhus, Denmark Show the Organization-Enhanced name(s) 56 Aalborg Univ Hosp, Aalborg, Denmark 57 Odense Univ Hosp, Odense, Denmark 58 Natl Canc Res Ctr, Madrid, Spain 59 Spanish Network Rare Dis, Madrid, Spain Show the Organization-Enhanced name(s) 60 Hosp Clin San Carlos, Inst Invest Sanitaria, Madrid, Spain Show the Organization-Enhanced name(s) 61 Univ Hosp, Barcelona, Spain Show the Organization-Enhanced name(s) 62 Vall dHebron Inst Oncol, Barcelona, Spain 63 Univ Hosp Vall dHebron, Barcelona, Spain Show the Organization-Enhanced name(s) 64 Catalan Inst Oncol, Bellvitge Biomed Res Inst, Barcelona, Spain Show the Organization-Enhanced name(s) 65 Catalan Inst Oncol, Inst Invest Biomed Girona, Girona, Spain 66 Natl Ctr Sci Res Demokritos, Athens, Greece Show the Organization-Enhanced name(s) 67 German Canc Res Ctr, Heidelberg, Germany Show the Organization-Enhanced name(s) 68 Univ Hosp Heidelberg, Heidelberg, Germany Show the Organization-Enhanced name(s) 69 Tech Univ Munich, Klinikumrechts Isar, Munich, Germany Show the Organization-Enhanced name(s) 70 Ludwig Maximilians Univ Munchen, Munich, Germany Show the Organization-Enhanced name(s) 71 Univ Wurzburg, Wurzburg, Germany Show the Organization-Enhanced name(s) 72 Univ Munster, Munster, Germany Show the Organization-Enhanced name(s) 73 Univ Leipzig, Leipzig, Germany Show the Organization-Enhanced name(s) 74 Univ Hosp, Leipzig, Germany Show the Organization-Enhanced name(s) 75 Heinrich Heine Univ, Univ Hosp Dusseldorf, Dusseldorf, Germany Show the Organization-Enhanced name(s) 76 Hannover Med Sch, Hannover, Germany Show the Organization-Enhanced name(s) 77 Univ Hosp Cologne, Cologne, Germany Show the Organization-Enhanced name(s) 78 Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dresden, Germany Show the Organization-Enhanced name(s) 79 Christian Albrechts Univ Kiel, Univ Hosp Schleswig Holstein, Kiel, Germany Show the Organization-Enhanced name(s) 80 Univ Hosp Ulm, Ulm, Germany Show the Organization-Enhanced name(s) 81 Ctr Leon Berard, Lyon, France Show the Organization-Enhanced name(s) 82 Univ Lyon, Lyon, France Show the Organization-Enhanced name(s) 83 Inst Curie, Paris, France Show the Organization-Enhanced name(s) 84 Univ Ghent, Ghent, Belgium Show the Organization-Enhanced name(s) 85 Univ Helsinki, Helsinki, Finland Show the Organization-Enhanced name(s) 86 Helsinki Univ Hosp, Helsinki, Finland Show the Organization-Enhanced name(s) 87 Leiden Univ, Med Ctr, Leiden, Netherlands Show the Organization-Enhanced name(s) 88 Natl Inst Oncol, Budapest, Hungary Show the Organization-Enhanced name(s) 89 Univ Iceland, Landspitali Univ Hosp, Reykjavik, Iceland Show the Organization-Enhanced name(s) 90 Univ Iceland, Biomed Ctr, Reykjavik, Iceland Show the Organization-Enhanced name(s) 91 Portuguese Oncol Inst, Oporto, Portugal Show the Organization-Enhanced name(s) 92 Univ Porto, Oporto, Portugal Show the Organization-Enhanced name(s) 93 Ulsan Coll Med, Seoul, South Korea 94 Asan Med Ctr, Seoul, South Korea 95 Soonchunhyang Univ & Hosp, Seoul, South Korea Show the Organization-Enhanced name(s) 96 Daerim St Marys Hosp, Seoul, South Korea Show the Organization-Enhanced name(s) 97 Seoul Natl Univ, Coll Med, Seoul, South Korea Show the Organization-Enhanced name(s) 98 Soonchunhyang Univ, Bucheon Hosp, Bucheon, South Korea Show the Organization-Enhanced name(s) 99 Med Univ Vienna, Vienna, Austria 100 Sime Darby Med Ctr, Subang Jaya, Malaysia Show the Organization-Enhanced name(s) 101 Karolinska Univ Hosp, Stockholm, Sweden

مصطلحات موضوعية: Brjóstakrabbamein, Blöðruhálskirtilskrabbamein, Gen, Karlar, MAO12, PTT12, NAF12, Genes, BRCA1, BRCA2, Mutation, Breast Neoplasms, Male, Prostatic Neoplasms

العلاقة: Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. 2017, 35 (20):2240-2250 J. Clin. Oncol.; http://hdl.handle.net/2336/620286Test; Journal of clinical oncology : official journal of the American Society of Clinical Oncology

الإتاحة: https://doi.org/10.1200/JCO.2016.69.4935Test
http://hdl.handle.net/2336/620286Test

المؤلفون: Fritsche, Lars G, Chen, Wei, Schu, Matthew, Yaspan, Brian L, Yu, Yi, Thorleifsson, Gudmar, Zack, Donald J, Arakawa, Satoshi, Cipriani, Valentina, Ripke, Stephan, Igo, Robert P, Buitendijk, Gabriëlle H S, Sim, Xueling, Weeks, Daniel E, Guymer, Robyn H, Merriam, Joanna E, Francis, Peter J, Hannum, Gregory, Agarwal, Anita, Armbrecht, Ana Maria, Audo, Isabelle, Aung, Tin, Barile, Gaetano R, Benchaboune, Mustapha, Bird, Alan C, Bishop, Paul N, Branham, Kari E, Brooks, Matthew, Brucker, Alexander J, Cade, William H, Cain, Melinda S, Campochiaro, Peter A, Chan, Chi-Chao, Cheng, Ching-Yu, Chew, Emily Y, Chin, Kimberly A, Chowers, Itay, Clayton, David G, Cojocaru, Radu, Conley, Yvette P, Cornes, Belinda K, Daly, Mark J, Dhillon, Baljean, Edwards, Albert O, Evangelou, Evangelos, Fagerness, Jesen, Ferreyra, Henry A, Friedman, James S, Geirsdottir, Asbjorg, George, Ronnie J, Gieger, Christian, Gupta, Neel, Hagstrom, Stephanie A, Harding, Simon P, Haritoglou, Christos, Heckenlively, John R, Holz, Frank G, Hughes, Guy, Ioannidis, John P A, Ishibashi, Tatsuro, Joseph, Peronne, Jun, Gyungah, Kamatani, Yoichiro, Katsanis, Nicholas, N Keilhauer, Claudia, Khan, Jane C, Kim, Ivana K, Kiyohara, Yutaka, Klein, Barbara E K, Klein, Ronald, Kovach, Jaclyn L, Kozak, Igor, Lee, Clara J, Lee, Kristine E, Lichtner, Peter, Lotery, Andrew J, Meitinger, Thomas, Mitchell, Paul, Mohand-Saïd, Saddek, Moore, Anthony T, Morgan, Denise J, Morrison, Margaux A, Myers, Chelsea E, Naj, Adam C, Nakamura, Yusuke, Okada, Yukinori, Orlin, Anton, Ortube, M Carolina, Othman, Mohammad I, Pappas, Chris, Park, Kyu Hyung, Pauer, Gayle J T, Peachey, Neal S, Poch, Olivier, Priya, Rinki Ratna, Reynolds, Robyn, Richardson, Andrea J, Ripp, Raymond, Rudolph, Guenther, Ryu, Euijung, Sahel, José-Alain, Schaumberg, Debra A, Scholl, Hendrik P N, Schwartz, Stephen G, Scott, William K, Shahid, Humma, Sigurdsson, Haraldur, Silvestri, Giuliana, Sivakumaran, Theru A, Smith, R Theodore, Sobrin, Lucia, Souied, Eric H, Stambolian, Dwight E, Stefansson, Hreinn, Sturgill-Short, Gwen M, Takahashi, Atsushi, Tosakulwong, Nirubol, Truitt, Barbara J, Tsironi, Evangelia E, Uitterlinden, André G, van Duijn, Cornelia M, Vijaya, Lingam, Vingerling, Johannes R, Vithana, Eranga N, Webster, Andrew R, Wichmann, H-Erich, Winkler, Thomas W, Wong, Tien Y, Wright, Alan F, Zelenika, Diana, Zhang, Ming, Zhao, Ling, Zhang, Kang, Klein, Michael L, Hageman, Gregory S, Lathrop, G Mark, Stefansson, Kari, Allikmets, Rando, Baird, Paul N, Gorin, Michael B, Wang, Jie Jin, Klaver, Caroline C W, Seddon, Johanna M, Pericak-Vance, Margaret A, Iyengar, Sudha K, Yates, John R W, Swaroop, Anand, Weber, Bernhard H F, Kubo, Michiaki, Deangelis, Margaret M, Léveillard, Thierry, Thorsteinsdottir, Unnur, Haines, Jonathan L, Farrer, Lindsay A, Heid, Iris M, Abecasis, Gonçalo R

المساهمون: 2 Univ Michigan, Dept Biostat, Ctr Stat Genet, Ann Arbor, MI 48109 USA 3 Univ Pittsburgh, Childrens Hosp Pittsburgh, Sch Med,Med Ctr, Div Pediat Pulm Med Allergy & Immunol,Dept Pediat, Pittsburgh, PA USA 4 Boston Univ, Sch Med, Dept Med, Sect Biomed Genet, Boston, MA 02118 USA 5 Boston Univ, Sch Publ Hlth, Dept Med, Sect Biomed Genet, Boston, MA USA 6 Vanderbilt Univ, Med Ctr, Ctr Human Genet Res, Nashville, TN USA 7 Vanderbilt Univ, Dept Mol Physiol & Biophys, Sch Med, Nashville, TN 37232 USA 8 Tufts Med Ctr, Ophthalm Epidemiol & Genet Serv, Boston, MA USA 9 deCODE Genet, Reykjavik, Iceland 10 Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Dept Mol Biol & Genet, Baltimore, MD 21205 USA 11 Univ Paris 06, Dept Genet, Inst Vis, UMRS 968, Paris, France 12 Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Dept Neurosci, Baltimore, MD 21205 USA 13 Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Inst Genet Med, Baltimore, MD 21205 USA 14 RIKEN, CGM, Res Grp Genotyping, Lab Genotyping Dev, Yokohama, Kanagawa, Japan 15 Moorfields Eye Hosp, London, England 16 UCL, Inst Ophthalmol, London, England 17 Massachusetts Gen Hosp, Analyt & Translat Genet Unit, Boston, MA 02114 USA 18 Broad Inst Harvard & MIT, Stanley Ctr Psychiat Res, Cambridge, MA USA 19 Case Western Reserve Univ, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA 20 Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands 21 Erasmus MC, Dept Ophthalmol, Rotterdam, Netherlands 22 Natl Univ Singapore, Ctr Mol Epidemiol, Singapore 117548, Singapore 23 Univ Pittsburgh, Grad Sch Publ Hlth, Dept Human Genet, Pittsburgh, PA 15261 USA 24 Univ Pittsburgh, Grad Sch Publ Hlth, Dept Biostat, Pittsburgh, PA 15261 USA 25 Univ Melbourne, Royal Victorian Eye & Ear Hosp, Ctr Eye Res Australia, East Melbourne, Vic, Australia 26 Columbia Univ, Dept Ophthalmol, New York, NY 10027 USA 27 Oregon Hlth & Sci Univ, Casey Eye Inst, Macular Degenerat Ctr, Portland, OR 97201 USA 28 Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA 29 Vanderbilt Univ, Med Ctr, Vanderbilt Eye Inst, Nashville, TN USA 30 Vanderbilt Univ, Sch Med, Dept Ophthalmol & Visual Sci, Nashville, TN 37212 USA 31 Univ Edinburgh, Dept Ophthalmol, Edinburgh, Midlothian, Scotland 32 Princess Alexandra Eye Pavil, Edinburgh, Midlothian, Scotland 33 INSERM, U968, Paris, France 34 CNRS, UMR 7210, Paris, France 35 Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore 36 Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore 117595, Singapore 37 Ctr Invest Clin 503, Ctr Hosp Natl Ophtalmol Quinze Vingts, INSERM Direct Hosp & Org Soins, Paris, France 38 Univ Manchester, Fac Med & Human Sci, Inst Human Dev, Manchester, Lancs, England 39 Cent Manchester Univ Hosp Natl Hlth Serv NHS Fdn, Manchester Acad Hlth Sci Ctr, Manchester, Lancs, England 40 Univ Michigan, Dept Ophthalmol & Visual Sci, Ann Arbor, MI 48109 USA 41 NEI, Neurobiol Neurodegenerabon & Repair Lab N NNRL, US Natl Inst Hlth, Bethesda, MD 20892 USA 42 Penn Presbyterian Med Ctr, Scheie Eye Inst, Philadelphia, PA USA 43 Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA 44 Univ Miami, Miller Sch Med, Dr John T Macdonald Fdn Dept Human Genet, Miami, FL 33136 USA 45 Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Dept Ophthalmol, Baltimore, MD 21205 USA 46 NEI, Immunopathol Sect, Immunol Lab, US Natl Inst Hlth, Bethesda, MD USA 47 Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117548, Singapore 48 Duke Natl Univ Singapore Grad Med Sch, Off Clin Sci, Ctr Quantitat Med, Singapore, Singapore 49 NEI, Div Epidemiol & Clin Applicat, US Natl Inst Hlth, Bethesda, MD 20892 USA 50 Hadassah Hebrew Univ Med Ctr, Dept Ophthalmol, Jerusalem, Israel 51 Univ Cambridge, Cambridge Inst Med Res, Dept Med Genet, Cambridge, England 52 Univ Pittsburgh, Sch Nursing, Dept Hlth Promot & Dev, Pittsburgh, PA 15261 USA 53 Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA 54 Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, Greece 55 Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA 56 Broad Inst Harvard & MIT, Program Med & Populat Genet, Cambridge, MA USA 57 Univ Calif San Diego, Dept Ophthalmol, La Jolla, CA 92093 USA 58 Univ Calif San Diego, Shiley Eye Ctr, La Jolla, CA 92093 USA 59 Natl Univ Hosp Reykjavik, Dept Ophthalmol, Reykjavik, Iceland 60 Vis Res Fdn, Glaucoma Project, Madras, Tamil Nadu, India 61 Deutsch Forschungszentrum Gesundheit & Umwelt, Helmholtz Zentrum Manchen, Inst Genet Epidemiol, Neuherberg, Germany 62 Cleveland Clin Fdn, Cole Eye Inst, Cleveland, OH 44195 USA 63 Univ Liverpool, Dept Eye & Vis Sci, Inst Ageing & Chron Dis, Liverpool L69 3BX, Merseyside, England 64 Univ Munich, Augenklin, D-80539 Munich, Germany 65 Univ Bonn, Dept Ophthalmol, Bonn, Germany 66 Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA 67 Stanford Univ, Dept Med, Sch Med, Stanford Prevent Res Ctr, Stanford, CA 94305 USA 68 Stanford Univ, Sch Med, Dept Hlth Res & Policy, Stanford, CA 94305 USA 69 Stanford Univ, Dept Stat, Sch Humanities & Sci, Stanford, CA 94305 USA 70 Kyushu Univ, Grad Sch Med Sci, Dept Ophthalmol, Fukuoka, Japan 71 Boston Univ, Sch Med, Dept Ophthalmol, Boston, MA 02118 USA 72 Boston Univ, Sch Publ Hlth, Dept Ophthalmol, Boston, MA 02118 USA 73 Boston Univ, Sch Med, Dept Biostat, Boston, MA 02118 USA 74 Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA 75 Ctr Etud Polymorphisme Humain CEPH, Fdn Jean Dausset, Paris, France 76 Duke Univ, Ctr Human Dis Modeling, Durham, NC USA 77 Duke Univ, Dept Cell Biol, Durham, NC USA 78 Duke Univ, Dept Pediat, Durham, NC 27706 USA 79 Univ Wurzburg, Dept Ophthalmol, D-97070 Wurzburg, Germany 80 Royal Perth Hosp, Dept Ophthalmol, Perth, WA, Australia 81 Univ Western Australia, Ctr Ophthalmol & Visual Sci, Perth, WA 6009, Australia 82 Harvard Univ, Sch Med, Dept Ophthalmol, Boston, MA USA 83 Massachusetts Eye & Ear Infirm, Boston, MA 02114 USA 84 Kyushu Univ, Grad Sch Med Sci, Dept Environm Med, Fukuoka, Japan 85 Univ Wisconsin, Sch Med, Dept Ophthalmol & Visual Sci, Madison, WI USA 86 Univ Wisconsin, Sch Publ Hlth, Dept Ophthalmol & Visual Sci, Madison, WI USA 87 Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Miami, FL 33136 USA 88 Deutsch Forschungszentrum Gesundheit & Umwelt, Helmholtz Zentrum Munchen, Inst Human Genet, Neuherberg, Germany 89 Univ Southampton, Fac Med Clin & Expt Sci, Southampton, Hants, England 90 Tech Univ Munich, Inst Human Genet, D-80290 Munich, Germany 91 Univ Sydney, Dept Ophthalmol, Ctr Vis Res, Sydney, NSW 2006, Australia 92 Univ Sydney, Westmead Millennium Inst, Sydney, NSW 2006, Australia 93 Univ Paris 06, Dept Therapeut, Inst Vis, UMRS 968, Paris, France 94 Univ Utah, Dept Ophthalmol & Visual Sci, John A Moran Eye Ctr, Salt Lake City, UT USA 95 Univ Tokyo, Inst Med Sci, Ctr Human Genome, Lab Mol Med, Tokyo, Japan 96 RIKEN, Lab Stat Anal, Yokohama, Kanagawa, Japan 97 Weill Cornell Med Coll, Dept Ophthalmol, New York, NY USA 98 Univ Calif Los Angeles, David Geffen Sch Med, Dept Ophthalmol, Los Angeles, CA 90095 USA 99 Jules Stein Eye Inst, Los Angeles, CA 90024 USA 100 Univ Utah, Moran Ctr Translat Med, John A Moran Eye Ctr, Salt Lake City, UT USA 101 Seoul Natl Univ, Bundang Hosp, Dept Ophthalmol, Kyeounggi, South Korea 102 Louis Stokes Vet Affairs Med Ctr, Res Serv, Cleveland, OH USA 103 IGBMC, Lab Integrat Bioinformat & Genom, Illkirch Graffenstaden, France 104 Mayo Clin, Div Biomed Stat & Informat, Rochester, MN USA 105 Fdn Ophtalmol Adolphe Rothschild, Paris, France 106 Acad Sci Inst France, Paris, France 107 Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA 108 Addenbrookes Hosp, Dept Ophthalmol, Cambridge, England 109 Univ Iceland, Fac Med, Reykjavik, Iceland 110 Queens Univ Belfast, Ctr Vis & Vasc Sci, Belfast, Antrim, North Ireland 111 Cincinnati Childrens Hosp Med Ctr, Div Human Genet, Cincinnati, OH USA 112 Columbia Univ, Dept Biomed Engn, New York, NY USA 113 Univ Paris Est, Hop Henri Mondor, Ctr Rech Clin Ophthalmol, Hop Intercommunal Creteil, Creteil, France 114 Univ Penn, Dept Ophthalmol & Genet, Philadelphia, PA 19104 USA 115 Univ Thessaly, Sch Med, Dept Ophthalmol, Larisa, Greece 116 Erasmus MC, Dept Internal Med, Rotterdam, Netherlands 117 Deutsch Forschungszentrum Gesundheit & Umwelt, Helmholtz Zentrum Munchen, Inst Epidemiol 1, Neuherberg, Germany 118 Univ Munich, Inst Med Informat, Munich, Germany 119 Univ Munich, Klinikum Grosshadern, D-80539 Munich, Germany 120 Univ Munich, Inst Biometry, Munich, Germany 121 Univ Munich, Inst Epidemiol, Munich, Germany 122 Univ Regensburg, Dept Epidemiol & Prevent Med, D-93053 Regensburg, Germany 123 Inst Genet & Mol Med, Med Res Council Human Genet Unit, Edinburgh, Midlothian, Scotland 124 Ctr Energie Atom, Inst Genom, Ctr Natl Genotypage, Evry, France 125 Sichuan Univ, West China Hosp, Mol Med Res Ctr, Chengdu 610064, Peoples R China 126 Sichuan Univ, West China Hosp, Dept Ophthalmol, Chengdu 610064, Peoples R China 127 Columbia Univ, Dept Pathol & Cell Biol, New York, NY USA 128 Univ Calif Los Angeles, David Geffen Sch Med, Dept Human Genet, Los Angeles, CA 90095 USA 129 Tufts Univ, Sch Med, Dept Ophthalmol, Boston, MA 02111 USA 130 Case Western Reserve Univ, Dept Genet, Cleveland, OH 44106 USA 131 Case Western Reserve Univ, Dept Ophthalmol & Visual Sci, Cleveland, OH 44106 USA 132 Case Western Reserve Univ, Ctr Clin Invest, Cleveland, OH 44106 USA 133 Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA 134 Boston Univ, Sch Publ Hlth, Dept Neurol, Boston, MA USA 135 Boston Univ, Sch Med, Dept Epidemiol, Boston, MA USA 136 Boston Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

مصطلحات موضوعية: Sjónhimna, Sjónskerðing, Erfðasjúkdómar, Biological Markers, Case-Control Studies, Female, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Macular Degeneration, Male, Meta-Analysis as Topic, Polymorphism, Single Nucleotide, Risk Factors

العلاقة: http://dx.doi.org/10.1038/ng.2578Test; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739472Test/; Nat. Genet. 2013, 45 (4):433-9, 439e1-2; http://hdl.handle.net/2336/324724Test; Nature genetics

الإتاحة: https://doi.org/10.1038/ng.2578Test
http://hdl.handle.net/2336/324724Test