المؤلفون: Lawrenson, Kate, Kar, Siddhartha, McCue, Karen, Kuchenbaeker, Karoline, Michailidou, Kyriaki, Tyrer, Jonathan, Beesley, Jonathan, Ramus, Susan J, Li, Qiyuan, Delgado, Melissa K, Lee, Janet M, Barkardottir, Rosa B, García-Closas, Montserrat, Gentry-Maharaj, Aleksandra, Torres, Diana, Hall, Per, John, Esther M, Ghoussaini, Maya, Giles, Graham G, Mazoyer, Sylvie, Wu, Anna H, Harrington, Patricia A, Laitman, Yael, Glasspool, Rosalind, Godwin, Andrew K, Goldberg, Mark S, Goldgar, David E, Høgdall, Claus K, Shah, Mitul, Johnson, Nichola, Wang-Gohrke, Shan, González-Neira, Anna, French, Juliet D, Hartman, Mikael, Terry, Mary Beth, Goodman, Marc T, Goode, Ellen L, Lambrechts, Diether, Hogervorst, Frans B L, McGuffog, Lesley, Hollestelle, Antoinette, Hopper, John L, Thomassen, Mads, Couch, Fergus J, Shen, Chen-Yang, Hulick, Peter J, Andrulis, Irene L, De Leeneer, Kim, Anton-Culver, Hoda, Kabisch, Maria, Brauch, Hiltrud, Daly, Mary B, Wentzensen, Nicolas, Kang, Daehee, Meindl, Alfons, Kapuscinski, Miroslav, McNeish, Iain, Toland, Amanda Ewart, Karlan, Beth Y, Osorio, Ana, Khan, Sofia, Kiemeney, Lambertus A, Whittemore, Alice S, Brennan, Paul, Tibiletti, Maria Grazia, Arver, Brita, Knight, Julia A, Kjaer, Susanne Kruger, Menon, Usha, Rhenius, Valerie, Lester, Jenny, Levine, Douglas A, Cox, Angela, Flyger, Henrik, Arun, Banu K, Li, Jingmei, Butzow, Ralf, Pejovic, Tanja, Lindblom, Annika, Pearce, Celeste L, Yoon, Sook-Yee, Rhiem, Kerstin, Long, Jirong, Lophatananon, Artitaya, Loud, Jennifer T, Lu, Karen, Bandera, Elisa V, Freedman, Matthew L, Cramer, Daniel W, Wildiers, Hans, Olah, Edith, Mannermaa, Arto, Lubinski, Jan, Risch, Harvey A, Peterlongo, Paolo, Shu, Xiao-Ou, Mensenkamp, Arjen R, Milne, Roger L, Easton, Douglas F, Evans, D Gareth, Hansen, Thomas V O, Montagna, Marco, Moysich, Kirsten B, Dennis, Joe, Olson, Janet E, Rodriguez, Gus, Muir, Kenneth, Mulligan, Anna Marie, Bisogna, Maria, Foretova, Lenka, Sieh, Weiva, Nathanson, Katherine L, Ness, Roberta B, Neuhausen, Susan L, Nevanlinna, Heli, Pfeiler, Georg, Brenner, Hermann, Rossing, Mary Anne, Fasching, Peter A, Barile, Monica, Orr, Nick, Cross, Simon S, Nussbaum, Robert L, Nord, Silje, Singer, Christian F, Phelan, Catherine M, Tognazzo, Silvia, Poole, Elizabeth M, Pylkäs, Katri, Cybulski, Cezary, Bruinsma, Fiona, Barrowdale, Daniel, Greene, Mark H, Slager, Susan, Gronwald, Jacek, Rudolph, Anja, Huzarski, Tomasz, Kwong, Ava, Figueroa, Jonine, Beckmann, Matthias W, Salvesen, Helga B, Tomlinson, Ian, Dansonka-Mieszkowska, Agnieszka, Sangrajrang, Suleeporn, Yannoukakos, Drakoulis, Sawyer, Elinor J, Schildkraut, Joellen M, Flesch-Janys, Dieter, Imyanitov, Evgeny N, Czene, Kamila, Schmutzler, Rita K, Schmidt, Marjanka K, Truong, Thérèse, Dunning, Alison M, Song, Honglin, Soucy, Penny, Konstantopoulou, Irene, Matsuo, Keitaro, Haiman, Christopher A, Southey, Melissa C, Zheng, Wei, Stenmark-Askmalm, Marie, Yu, Jyh-Cherng, Foulkes, William D, Pharoah, Paul D, Stoppa-Lyonnet, Dominique, Berchuck, Andrew, Sutter, Christian, Swerdlow, Anthony, Hallberg, Emily, Kosma, Veli-Matti, Fletcher, Olivia, Weitzel, Jeffrey N, Teixeira, Manuel R, Tchatchou, Sandrine, Edwards, Stacey L, Zheng, Ying, Brunet, Joan, Tseng, Chiu-Chen, Tung, Nadine, Manoukian, Siranoush, Orlow, Irene, Tworoger, Shelley S, Vachon, Celine, Le, Nhu, Blomqvist, Carl, Chenevix-Trench, Georgia, van den Ouweland, Ans M W, Bjorge, Line, Healey, Sue, Buhari, Shaik Ahmad, van Doorn, Helena C, van Rensburg, Elizabeth J, Van't Veer, Laura J, Vanderstichele, Adriaan, Khanna, Kum Kum, Isaacs, Claudine, Bogdanova, Natalia, Le Marchand, Loic, Hamann, Ute, Arndt, Volker, Vijai, Joseph, Vergote, Ignace, Burwinkel, Barbara, Blot, William, Damiola, Francesca, Simard, Jacques, Monteiro, Alvaro N, Kristensen, Vessela, Ito, Hidemi, Odunsi, Kunle, Buys, Saundra S, Offit, Kenneth, Antoniou, Antonis C, Radice, Paolo, Benitez, Javier, Margolin, Sara, Aittomäki, Kristiina, Gayther, Simon A, Darabi, Hatef, Bojesen, Anders, Fostira, Florentia, Bojesen, Stig E, Bolla, Manjeet K, Marme, Frederik, Rantala, Johanna, Kupryjanczyk, Jolanta, Børresen-Dale, Anne-Lise, Bonanni, Bernardo, Devilee, Peter, Cai, Qiuyin, Caldes, Trinidad, Sellers, Thomas A, Tihomirova, Laima, Olopade, Olufunmilayo I, Campbell, Ian, Friedman, Eitan, Canniotto, Rikki, Fridley, Brooke L, McLean, Catriona, Chang-Claude, Jenny, Hassan, Norhashimah, Chiquette, Jocelyne, Choi, Ji-Yeob, Olswold, Curtis, Seynaeve, Caroline, Massuger, Leon F A G, Feliubadalo, Lidia, Cook, Linda S, Claes, Kathleen B M, Frost, Debra, Jakubowska, Anna, Diez, Orland, Doherty, Jennifer A, Teo, Soo H, Winqvist, Robert, Domchek, Susan M, Dorfling, Cecilia M, Sinilnikova, Olga M, Herzog, Josef, Dörk, Thilo, Heitz, Florian, Park, Sue Kyung, Janavicius, Ramunas, Dumont, Martine, Ehrencrona, Hans, Ejlertsen, Bent, Ellis, Steve, Gambino, Gaetana, Rashid, Muhammad Usman, Terry, Kathryn L, O'Malley, David, Guénel, Pascal, Lee, Eunjung, Engel, Christoph, Jensen, Allan, Høgdall, Estrid, de la Hoya, Miguel, Ganz, Patricia A, Garber, Judy, Rennert, Gad, Wang, Qin

المساهمون: 1 Department of Preventive Medicine, Keck School of MediCenter, Kansas City, Kansas 66160, USA. 90 Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel. 91 Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa 56126, Italy. 92 UCLA Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California 90024, USA. 93 Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA. 94 Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK. 95Women’s Cancer, UCL EGA Institute for Women’s Health, London WC1E 6AU, UK. 96 Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia. 97 Cancer Research UK Clinical Trials Unit, The BeatsonWest of Scotland Cancer Centre, Glasgow G12 0YN, UK. 98 Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas 66160, USA. 99 Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Que´bec H3A 1A1, Canada. 100 Department of Medicine, McGill University, Montreal, Que´bec H3A 1A1, Canada. 101 Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA. 102 Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55902, USA. 103 Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA. 104Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA. 105 Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA. 106 Department of Genetics and Pathology, Pomeranian Medical University, 70-204 Szczecin, Poland. 107 Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, 94805 Villejuif, France. 108 University Paris- Sud, 91405 Villejuif, France. 109 Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. 110 Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark. 111 Department of Oncology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK. 112 Saw Swee Hock School of Public Health, National University of Singapore Singapore 119077, Singapore. 113 Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia. 114 Cancer Research Initiatives Foundation, Subang Jaya, 47500 Selangor, Malaysia. 115 Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, 45136 Essen, Germany. 116 Department of Gynecology and Gynecologic Oncology, Dr Horst Schmidt Kliniken Wiesbaden, 65199 Wiesbaden, Germany. 117 Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte California 91010, USA. 118 Molecular Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, 2730 Copenhagen, Denmark. 119 Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark. 120 Department of Gynecology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark. 121 Family Cancer Clinic, Netherlands Cancer Institute, 1006 Amsterdam, The Netherlands. 122 Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, 3015 Rotterdam, The Netherlands. 123 Center for Medical Genetics, NorthShore University Health System, Evanston, Illinois 60201, USA. 124 N.N. Petrov Institute of Oncology, St Petersburg 197758, Russia. 125 Lombardi Comprehensive Cancer Center, Georgetown University, Washington District of Columbia 20057, USA. 126 Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Aichi 464-8681, Japan. 127 State Research Institute Centre for Innovative Medicine, LT-01102 Vilnius, Lithuania. 128 Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California 94538, USA. 129 Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 08826, Korea. 130 Centre for Epidemiology and Biostatistics, University of Melbourne, Melbourne, Victoria 3010, Australia. 131Women’s Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA. 132 Radboud University Medical Centre, Radboud Institute for Health Sciences, 6500 Nijmegen, The Netherlands. 133 Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada. 134 Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario M5T 3M7, Canada. 135 Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, 70210 Kuopio, Finland. 136 Cancer Center, Kuopio University Hospital, 70210 Kuopio, Finland. 137 Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210 Kuopio, Finland. 138 Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, 1478 Oslo, Norway. 139 The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China. 140 Department of Surgery, The University of Hong Kong, Hong Kong, China. 141Vesalius Research Center, VIB, 3000 Leuven, Belgium. 142 Laboratory for Translational Genetics, Department of Oncology, University of Leuven, 3000 Leuven, Belgium. 143 Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 77 Stockholm, Sweden. 144 Division of Health Sciences, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK. 145 Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. 146 Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), 20133 Milan, Italy. 147 University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA. 148 Department of Oncology - Pathology, Karolinska Institutet, SE- 171 77 Stockholm, Sweden. 149 National Center for Tumour Diseases, University of Heidelberg, 69117 Heidelberg, Germany. 150 Department of Gynaecology, Radboud University Medical Centre, 6500 Nijmegen, The Netherlands. 151 Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences, Fukuoka 812-8582, Japan. 152 Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria 3004, Australia. 153 Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research, Glasgow G61 1BD, UK. 154 Division of Gynaecology and Obstetrics, Technische Universita¨t Mu¨nchen, 81675 Munich, Germany. 155 Department of Human Genetics, Radboud University Medical Centre, 6500 Nijmegen, The Netherlands. 156 Immunology and Molecular Oncology Unit, Instituto Oncologico Veneto IOV, IRCCS, 35128 Padua, Italy. 157 Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. 158 Institute of Population Health, University of Manchester, Manchester M13 9PL, UK. 159 Laboratory Medicine Program, University Health Network, Toronto, Ontario M5G 1L7, Canada. 160 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 1L7, Canada. 161 The University of Texas School of Public Health, Houston, Texas 77030, USA. 162 Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA. 163 Department of Medicine and Genetics, University of California, San Francisco, California 94143, USA. 164 Department of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. 165 Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York 10065, USA. 166 Department of Molecular Genetics, National Institute of Oncology, 1122 Budapest, Hungary. 167 Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois 60637, USA. 168 The Ohio State University and the James Cancer Center, Columbus, Ohio 43210, USA. 169 Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York 10017, USA. 170 Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28019 Madrid, Spain. 171 Biomedical Network on Rare Diseases (CIBERER), 28029 Madrid, Spain. 172 Department of Surgery, Seoul National University College of Medicine, Seoul, 03080 Korea. 173 Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA. 174 Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon 97239, USA. 175 IFOM, The FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, 16 20139 Milan, Italy. 176 Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria. 177 Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida 33606, USA. 178 Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA. 179 Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts 02115, USA. 180 Laboratory of Cancer Genetics and Tumour Biology, Northern Finland Laboratory Centre NordLab, FI-90014 Oulu, Finland. 181 Laboratory of Cancer Genetics and Tumour Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland. 182 Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT),cine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA. 2 Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK. 3 QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia. 4 Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK. 5 Medical College, Xiamen University, Xiamen 361102, China. 6 Department of Medical Oncology, The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA. 7 Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki 00029 HUS, Finland. 8 Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario Canada, M5G 1X5. 9 Department of Molecular Genetics, University of Toronto, Toronto, OntarioCanada, M5S 1A8. 10 Department of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, California 92697, USA. 11 Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany. 12 University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. 13 Department of Oncology, Karolinska University Hospital, Stockholm 171 77, Sweden. 14 Cancer Prevention and Control, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey 08903, USA. 15 Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan 20141, Italy. 16 Department of Pathology, Landspitali University Hospital and BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik 600169- 2039, Iceland. 17 University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen 91054, Germany. 18 Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid E-28029, Spain. 19 Centro de Investigacio´n en Red de Enfermedades Raras, Valencia 28029, Spain. 20 Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina 27710, USA. 21 Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York 10065, USA. 22 Department of Gynecology and Obstetrics, Haukeland University Hospital, 5021 Bergen, Norway. 23 Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, N-5020 Bergen, Norway. 24 Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki FIN-00029, Finland. 25 Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA. 26 International Epidemiology Institute, Rockville, Maryland 20850, USA. 27 Gynaecology Research Unit, Hannover Medical School, Hannover D-30625, Germany. 28 Department of Clinical Genetics, Vejle Hospital, Vejle 7100, Denmark. 29 Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark. 30 Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev 2730, Denmark. 31 Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev 2730, Denmark. 32 Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo N-0310, Norway. 33 K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo N-0310, Norway. 34 Dr Margarete Fischer- Bosch-Institute of Clinical Pharmacology, Stuttgart D-70376, Germany. 35 University of Tu¨bingen, Tu¨bingen 72074, Germany. 36 German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. 37 International Agency for Research on Cancer, Lyon 69008, France. 38 Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany. 39 Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia. 40 Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d’Investigacio´ Biome`dica de Girona), Catalan Institute of Oncology, Girona 08908, Spain. 41 Department of Surgery, National University Health System, Singapore 119077, Singapore. 42 Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. 43 Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg 69120, Germany. 44 Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki 00029 HUS, Finland. 45 Department of Pathology, Helsinki University Central Hospital, Helsinki 00029, Finland. 46 Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA. 47 Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC (El Instituto de Investigacio´n Sanitaria del Hospital Clı ´nico San Carlos), Madrid 28040, Spain. 48 Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria 3002, Australia. 49 Cancer Pathology & Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo 14263, New York, USA. 50 Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany. 51 University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany. 52 Unite´ de recherche en sante´ des populations, Centre des maladies du sein Descheˆnes-Fabia, Centre de recherche FRSQ du Centre hospitalier affilie´ universitaire de Que´bec, Que´bec City, Que´bec Canada, G1J 1Z4. 53 Cancer Research Institute, Seoul National University, Seoul 08826, Korea. 54 Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea. 55 Center for Medical Genetics, Ghent University, Ghent 9000, Belgium. 56 Division of Epidemiology and Biostatistics, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico 87131, USA. 57 Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield S10 2TN, UK. 58 Harvard HT Chan School of Public Health, Boston, Massachusetts 02115, USA. 59 Obstetrics and Gynecology Epidemiology Center, Brigham andWomen’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA. 60 Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2TN, UK. 61 Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 70-115, Poland. 62 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm SE-171 77, Sweden. 63 Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA. 64 INSERM U1052, CNRS UMR5286, Universite´ Lyon, Centre de Recherche en Cance´rologie de Lyon, Lyon 69373, France. 65 Department of Pathology and Laboratory Diagnostics the Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology,Warsaw 44-101, Poland. 66 Department of Pathology, Leiden University Medical Center, Leiden 2333, The Netherlands. 67 Department of Human Genetics, Leiden University Medical Center, Leiden 2333, The Netherlands. 68 Oncogenetics Group, University Hospital Vall d’Hebron, Vall d’Hebron Institute of Oncology (VHIO) and Universitat Auto`noma de Barcelona, Barcelona, 186 Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics and Centre for Integrated Oncology (CIO), Center for Molecular Medicine Cologne (CMMC), University Hospital of Cologne, 50931 Cologne, Germany. 187Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut 06510, USA. 188Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois 60201, USA. 189 Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA. 190Department of Epidemiology, University of Washington, Seattle, Washington 98109, USA. 191National Cancer Institute, Bangkok 10400, Thailand. 192 Research Oncology, Guy’s Hospital, King’s College London, London SE1 9RT, UK. 193Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA. 194 Cancer Control and Population Sciences, Duke Cancer Institute, Durham, North Carolina 27710, USA. 195Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands. 196Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, 50676 Cologne, Germany. 197 Center for Integrated Oncology, University Hospital of Cologne, 50676 Cologne, Germany. 198 Center for Molecular Medicine, University Hospital of Cologne, 50676 Cologne, Germany. 199 Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, 50676 Cologne, Germany. 200 Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan. 201 School of Public Health, China Medical University, Taichung 404, Taiwan. 202Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, Stanford California 94305, USA. 203 Unite´ Mixte de Ge´ne´tique Constitutionnelle des Cancers Fre´quents, Hospices Civils de Lyon – Centre Le´on Be´rard, Lyon 69008, France. 204 INSERM U1052, CNRS UMR5286, Universite´ Lyon 1, Centre de Recherche en Cance´rologie de Lyon, Lyon 69003, France. 205Department of Pathology, University of Melbourne, Parkville, Victoria 3010, Australia. 206Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linko¨ping University, 581 83 Linko¨ping, Sweden. 207 Institut Curie, Department of Tumour Biology, Paris, France, Institut Curie, INSERM U830, 75248 Paris, France. 208Universite´ Paris Descartes, Sorbonne Paris Cite´, 75270 Paris, France. 209 Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany. 210Department of Genetics, Portuguese Oncology Institute, Porto 4200-072, Portugal. 211 Biomedical Sciences Institute (ICBAS), Porto University, Porto 4099-002, Portugal. 212Department of Epidemiology, Mailman School of Public Health, Columbia University, New York 10027, USA. 213Department of Clinical Genetics, Odense University Hospital, 5000 Odense C, Denmark. 214UO Anatomia Patologica, Ospedale di Circolo-Universita` dell’Insubria, 21100 Varese, Italy. 215 Latvian Biomedical Research and Study Centre, Riga LV-1067, Latvia. 216 Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico), 64 - 35128 Padua, Italy. 217Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio 43210, USA. 218Wellcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7BN, UK. 219 Institute of Human Genetics, Pontificia Universidad Javeriana, Cra. 7 #40-62 Bogota, Colombia. 220Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. 221Department of Clinical Genetics, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands. 222Department of Gynecology, Family Cancer Clinic, Erasmus MC Cancer Institute, 3015 CE Rotterdam, The Netherlands. 223Division of Gynecological Oncology, Department of Oncology, University Hospitals Leuven, B-3000 Leuven, Belgium. 224University Hospital Ulm, 89069 Ulm, Germany. 225Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda Maryland 20892, USA. 226 Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals Leuven, B-3000 Leuven, Belgium. 227 Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research ‘Demokritos’, Athens 153 10, Greece. 228 Cancer Research Initiatives Foundation, Sime Darby Medical Centre, 47500 Subang Jaya, Malaysia. 229 University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, 59100 Kuala Lumpur, Malaysia. 230Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114 Taiwan. 231 Shanghai Center for Disease Control and Prevention, Shanghai, China. 232 Cancer Epidemiology Program, Division of Population Sciences, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, USA. 233Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA. 234 Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia. 235 Sir Peter MacCallum Cancer Centre Department of Oncology, University of Melbourne, Parkville, Victoria 3052, Australia. 236 Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London W12 0HS, UK. 237 Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3052, Australia. 238 Department of Gynaecological Oncology, Westmead Institute for Cancer Research, Westmead Hospital Westmead, New South Wales 2145, Australia.

مصطلحات موضوعية: Brjóstakrabbamein, Arfgengi, Eggjastokkar, Krabbamein, NAF12, BRCA1 Protein/genetics, Breast Neoplasms/genetics, Chromosomes, Human, Pair 19/genetics, Genetic Predisposition to Disease, Ovarian Neoplasms/genetics

العلاقة: info:eu-repo/grantAgreement/EC/FP7/ 223175 info:eu-repo/grantAgreement/EC/FP7/223175; http://dx.doi.org/10.1038/ncomms12675Test; Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. 2016, 7:12675 Nat Commun; http://hdl.handle.net/2336/620021Test; Nature communications

الإتاحة: https://doi.org/10.1038/ncomms12675Test
http://hdl.handle.net/2336/620021Test

المؤلفون: Kuchenbaecker, Karoline B, Ramus, Susan J, Tyrer, Jonathan, Lee, Andrew, Shen, Howard C, Beesley, Jonathan, Lawrenson, Kate, McGuffog, Lesley, Healey, Sue, Lee, Janet M, Spindler, Tassja J, Kirk, Judy, Rodriguez, Gustavo C, Piedmonte, Marion, O'Malley, David M, de la Hoya, Miguel, Phelan, Catherine M, Caldes, Trinidad, Aittomäki, Kristiina, Nevanlinna, Heli, Kjaer, Susanne Kruger, Rosen, Barry, Collée, J Margriet, Rookus, Matti A, Oosterwijk, Jan C, Tihomirova, Laima, Tung, Nadine, Hamann, Ute, Isaccs, Claudine, Greene, Mark H, Tischkowitz, Marc, Imyanitov, Evgeny N, Risch, Harvey A, Terry, Mary Beth, Caligo, Maria A, Campbell, Ian G, Hogervorst, Frans B L, Olah, Edith, Diez, Orland, Blanco, Ignacio, Brunet, Joan, Lazaro, Conxi, Mai, Phuong L, McLaughlin, John R, Pujana, Miquel Angel, Montagna, Marco, Jakubowska, Anna, Gronwald, Jacek, Lubinski, Jan, Sukiennicki, Grzegorz, Barkardottir, Rosa B, Plante, Marie, Simard, Jacques, Soucy, Penny, Narod, Steven A, Rennert, Gad, Mulligan, Anna Marie, Hogdall, Estrid, Tchatchou, Sandrine, Pejovic, Tanja, Andrulis, Irene L, Glendon, Gord, Toland, Amanda Ewart, Jensen, Uffe Birk, Kruse, Torben A, Monteiro, Alvaro N, Thomassen, Mads, Bojesen, Anders, Zidan, Jamal, Hasmad, Hanis Nazihah, Friedman, Eitan, Laitman, Yael, Bean, Yukie, Soller, Maria, Liljegren, Annelie, Arver, Brita, Ding, Yuan Chun, Einbeigi, Zakaria, Stenmark-Askmalm, Marie, Olopade, Olufunmilayo I, Nussbaum, Robert L, Azmi, Mat Adenan Noor, Rebbeck, Timothy R, Nathanson, Katherine L, Domchek, Susan M, Li, Qiyuan, Lu, Karen H, Chen, Ann, Karlan, Beth Y, Walsh, Christine, Lester, Jenny, Hein, Alexander, Ekici, Arif B, Teo, Soo-Hwang, Beckmann, Matthias W, Fasching, Peter A, Lambrechts, Diether, Van Nieuwenhuysen, Els, Lin, Hui-Yi, Coetzee, Simon, Vergote, Ignace, Lambrechts, Sandrina, Dicks, Ed, Doherty, Jennifer A, Wicklund, Kristine G, Woo, Yin-Ling, Rossing, Mary Anne, Rudolph, Anja, Chang-Claude, Jenny, Permuth-Wey, Jenny, Wang-Gohrke, Shan, Eilber, Ursula, Hazelett, Dennis, Moysich, Kirsten B, Odunsi, Kunle, Sucheston, Lara, Lele, Shashi, Fridley, Brooke L, Wilkens, Lynne R, Goodman, Marc T, Vijai, Joseph, Thompson, Pamela J, Shvetsov, Yurii B, Runnebaum, Ingo B, Dürst, Matthias, Miron, Alexander, Hillemanns, Peter, Dörk, Thilo, Antonenkova, Natalia, Goode, Ellen L, Bogdanova, Natalia, du Bois, Andreas, Leminen, Arto, Pelttari, Liisa M, Butzow, Ralf, Modugno, Francesmary, Kelley, Joseph L, Edwards, Robert P, Southey, Melissa, Ness, Roberta B, Cunningham, Julie M, Vierkant, Robert A, Sellers, Thomas A, Bruinsma, Fiona, Tognazzo, Silvia, Goldgar, David E, Giles, Graham G, Liang, Dong, Hildebrandt, Michelle A T, Wu, Xifeng, Levine, Douglas A, Bisogna, Maria, Berchuck, Andrew, Tsai, Ya-Yu, Iversen, Edwin S, Schildkraut, Joellen M, Teixeira, Manuel R, Concannon, Patrick, Buys, Saundra S, Weber, Rachel Palmieri, Cramer, Daniel W, Terry, Kathryn L, Poole, Elizabeth M, Tworoger, Shelley S, Chen, Zhihua, Bandera, Elisa V, Orlow, Irene, Olson, Sara H, Pankratz, Vernon S, Krakstad, Camilla, Salvesen, Helga B, Janavicius, Ramunas, Tangen, Ingvild L, Bjorge, Line, van Altena, Anne M, Ziogas, Argyrios, Aben, Katja K H, Kiemeney, Lambertus A, Massuger, Leon F A G, Kellar, Melissa, Wang, Xianshu, Brooks-Wilson, Angela, Kelemen, Linda E, Cook, Linda S, Dorfling, Cecilia M, Le, Nhu D, Anton-Culver, Hoda, Cybulski, Cezary, Yang, Hannah, Lissowska, Jolanta, Brinton, Louise A, Wentzensen, Nicolas, Lindor, Noralane, Hogdall, Claus, Lundvall, Lene, Nedergaard, Lotte, Baker, Helen, Gentry-Maharaj, Aleksandra, van Rensburg, Elizabeth J, Song, Honglin, Eccles, Diana, McNeish, Ian, Paul, James, Carty, Karen, Szabo, Csilla I, Siddiqui, Nadeem, Glasspool, Rosalind, Whittemore, Alice S, Menon, Usha, Rothstein, Joseph H, McGuire, Valerie, Neuhausen, Susan L, Sieh, Weiva, Ji, Bu-Tian, Zheng, Wei, Shu, Xiao-Ou, Kauff, Noah, Gao, Yu-Tang, Hansen, Thomas V O, Harrington, Patricia, Lee, Alice W, Heitz, Florian, Aghajanian, Carol A, Wu, Anna H, Pearce, Celeste L, Coetzee, Gerry, Pike, Malcolm C, Dansonka-Mieszkowska, Agnieszka, Timorek, Agnieszka, Rzepecka, Iwona K, Kupryjanczyk, Jolanta, Jønson, Lars, Schwaab, Ira, Freedman, Matt, Lin, Yvonne G, Noushmehr, Houtan, Easton, Douglas F, Offit, Kenneth, Couch, Fergus J, Gayther, Simon, Pharoah, Paul P, Antoniou, Antonis C, Chenevix-Trench, Georgia, Harter, Philipp, Gerdes, Anne-Marie, Ejlertsen, Bent, Pfeiler, Georg, Barrowdale, Daniel, Dennis, Joe, Benitez, Javier, Osorio, Ana, Garcia, Maria Jose, Komenaka, Ian, Weitzel, Jeffrey N, Matsuo, Keitaro, Ganschow, Pamela, Peterlongo, Paolo, Bernard, Loris, Berger, Andreas, Viel, Alessandra, Bonanni, Bernardo, Peissel, Bernard, Manoukian, Siranoush, Radice, Paolo, Papi, Laura, Hosono, Satoyo, Ottini, Laura, Fostira, Florentia, Konstantopoulou, Irene, Garber, Judy, Singer, Christian F, Frost, Debra, Perkins, Jo, Platte, Radka, Ellis, Steve, Godwin, Andrew K, Orsulic, Sandra, Schmutzler, Rita Katharina, Meindl, Alfons, Engel, Christoph, Sutter, Christian, Sinilnikova, Olga M, Tea, Muy-Kheng, Damiola, Francesca, Mazoyer, Sylvie, Stoppa-Lyonnet, Dominique, Claes, Kathleen, Jensen, Allan, De Leeneer, Kim

المساهمون: 1 Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge, England 2 Univ So Calif, Kenneth Norris Jr Comprehens Canc Ctr, Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA 3 Univ Cambridge, Dept Oncol, Strangeways Res Lab, Cambridge, England 4 QIMR Berghofer Med Res Inst, Cancer Div, Brisbane, Qld, Australia 5 Univ So Calif, Dept Obstet & Gynaecol, Los Angeles, CA USA 6 Oregon Hlth & Sci Univ, Dept Obstet & Gynaecol, Portland, OR 97201 USA 7 Knight Canc Inst, Portland, OR USA 8 Ctr Funct Canc Epigenet, Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA 9 Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Genet, BR-14049 Ribeirao Preto, Brazil 10 Ctr Cell Based Therapy, Ribeirao Preto, Brazil 11 Ctr Integrat Syst Biol, Ribeirao Preto, Brazil 12 Univ So Calif, Dept Urol, Los Angeles, CA USA 13 Case Western Reserve Univ, Sch Med, Dept Genom & Genome Sci, Cleveland, OH 44106 USA 14 Univ Melbourne, Dept Pathol, Genet Epidemiol Lab, Parkville, Vic 3052, Australia 15 Columbia Univ, Dept Epidemiol, New York, NY USA 16 Univ Utah, Sch Med, Dept Dermatol, Salt Lake City, UT USA 17 Univ Utah, Sch Med, Huntsman Canc Inst, Dept Med, Salt Lake City, UT USA 18 Vilnius Univ Hosp Santariskiu Clin, Hematol Oncol & Transfus Med Ctr, Dept Mol & Regenerat Med, Vilnius, Lithuania 19 State Res Inst Ctr Innovat Med, Vilnius, Lithuania 20 Univ Pretoria, Dept Genet, ZA-0002 Pretoria, South Africa 21 City Hope Natl Med Ctr, Beckman Res Inst, Dept Populat Sci, Duarte, CA 91010 USA 22 Univ Copenhagen Hosp, Ctr Genet Med, DK-2100 Copenhagen, Denmark 23 Univ Copenhagen Hosp, Dept Clin Genet, DK-2100 Copenhagen, Denmark 24 Univ Copenhagen Hosp, Dept Oncol, DK-2100 Copenhagen, Denmark 25 Spanish Natl Canc Ctr CNIO, Human Canc Genet Program, Human Genet Grp, Madrid, Spain 26 Spanish Natl Canc Ctr CNIO, Human Canc Genet Program, Human Genotyping Unit CEGEN, Madrid, Spain 27 CIBERER, Biomed Network Rare Dis, Madrid, Spain 28 Maricopa Cty Gen Hosp, Clin Canc Genet Community Res Network, Duarte, CA USA 29 Clin Canc Genet, Clin Canc Genet Community Res Network, Duarte, CA USA 30 Cook Cty Hlth & Hosp Syst, Clin Canc Genet Community Res Network, Duarte, CA USA 31 Italian Fdn Canc Research, Fdn Ist FIRC Oncol Molecolare IFOM, Milan, Italy 32 Ist Europeo Oncol, Dept Expt Oncol, Milan, Italy 33 Cogentech Canc Genet Test Lab, Milan, Italy 34 CRO, Aviano Natl Canc Inst, Aviano, Italy 35 Ist Europeo Oncol, Div Canc Prevent & Genet, Milan, Italy 36 Italian Res Hospital, Fdn IRCCS, INT, Dept Prevent & Predict Med,Unit Med Genet, Milan, Italy 37 Fdn IRCCS, INT, Dept Prevent & Predict Med, Unit Mol Bases Genet Risk & Genet Testing, Milan, Italy 38 Univ Florence, Dept Biomed Expt & Clin Sci, Unit Med Genet, Florence, Italy 39 Univ Roma La Sapienza, Dept Mol Med, Rome, Italy 40 Natl Ctr Sci Res Demokritos, INRASTES Inst Nucl & Radiol Sci & Technology, Mol Diag Lab, Athens, Greece 41 Childrens Hosp, Dana Farber Canc Inst, Canc Risk & Prevent Clin, Boston, MA 02115 USA 42 Univ Kansas, Med Ctr, Dept Pathol & Lab Med, Kansas City, KS 66103 USA 43 Univ Hosp Cologne, Fac Med, Center Hereditary Breast & Ovarian Canc, Cologne, Germany 44 Univ Hosp Cologne, Fac Med, CIO, Cologne, Germany 45 Univ Hosp Cologne, CMMC, Cologne, Germany 46 Tech Univ Munich, Klinikum Rechts Isar, Dept Gynecol & Obstet, Div Tumor Genet, D-80290 Munich, Germany 47 Univ Leipzig, Inst Med Informat Stat & Epidemiol, D-04109 Leipzig, Germany 48 Heidelberg Univ, Inst Human Genet, Heidelberg, Germany 49 Univ Lyon, Ctr Rech Cancerol Lyon, CNRS UMR 5286, INSERM U1052, Lyon, France 50 Hosp Civils Lyon, Ctr Leon Berard, Unite Mixte Genet Constitutionnelle Canc Frequent, Lyon, France 51 Inst Curie, Dept Tumor Biol, Paris, France 52 Inst Curie, INSERM, U830, Paris, France 53 Univ Paris 05, Paris, France 54 Univ Ghent, Ctr Med Genet, B-9000 Ghent, Belgium 55 Westmead Hosp, ANZGOG, Sydney, NSW, Australia 56 Westmead Hosp, Familial Canc Serv, Sydney, NSW, Australia 57 NorthShore Univ HealthSystem, Div Gynecol Oncol, Evanston, IL USA 58 Roswell Pk Canc Inst, Stat & Data Ctr, Gynecol Oncol Grp, Buffalo, NY 14263 USA 59 Ohio State Univ, James Canc Ctr, Columbus, OH 43210 USA 60 Hosp Clin San Carlos, IdISSC Inst Invest Sanit Hosp Clin San Carlos, Mol Oncol Lab, Madrid, Spain 61 Univ Helsinki, Cent Hosp, Dept Clin Genet, Helsinki, Finland 62 Univ Helsinki, Dept Obstet & Gynaecol, Helsinki, Finland 63 Univ Helsinki, Cent Hosp, Helsinki, Finland 64 Erasmus Univ, Med Ctr, Family Canc Clin, Dept Clin Genet, Rotterdam, Netherlands 65 Netherlands Canc Inst, Dept Epidemiol, Amsterdam, Netherlands 66 Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands 67 Latvian Biomed Res & Study Ctr, Riga, Latvia 68 Beth Israel Deaconess Med Ctr, Dept Med Oncol, Boston, MA 02215 USA 69 DKFZ, Mol Genet Breast Canc, Heidelberg, Germany 70 Georgetown Univ, Lombardi Comprehens Canc Ctr, Washington, DC USA 71 McGill Univ, Program Canc Genet, Montreal, PQ, Canada 72 NN Petrov Inst Oncol, St Petersburg, Russia 73 Univ Pisa, Dept Lab Med, Sect Genet Oncol, Pisa, Italy 74 Univ Hosp Pisa, Pisa, Italy 75 Peter MacCallum Canc Ctr, VBCRC Canc Genet Lab, Melbourne, Vic, Australia 76 Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands 77 Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary 78 Univ Hosp Vall Hebron, VHIO, Oncogenet Grp, Barcelona, Spain 79 Univ Autonoma Barcelona, E-08193 Barcelona, Spain 80 Catalan Inst Oncol, IDIBELL Bellvitge Biomed Res Inst, Hereditary Canc Program, Genet Counseling Unit, Barcelona, Spain 81 Catalan Inst Oncol, IDIBGI Institut dInvestigacie Biomed Girona, Hereditary Canc Program, Genet Counseling Unit, Girona, Spain 82 Catalan Inst Oncol, IDIBELL, Hereditary Canc Program, Molecular Diagnost Unit, Barcelona, Spain 83 Pomeranian Med Univ, Dept Genet & Pathol, Szczecin, Poland 84 Landspitali Univ Hosp, Dept Pathol, Reykjavik, Iceland 85 Univ Iceland, Fac Med, Biomed Ctr, Reykjavik, Iceland 86 CHUQ, Gynaecol Oncol Serv, Quebec City, PQ, Canada 87 Univ Laval, CHUQ, Res Ctr, Quebec City, PQ, Canada 88 IRCCS, IOV, Immunol & Mol Oncol Unit, Padua, Italy 89 Univ Porto, Inst Biomed Sci ICBAS, P-4100 Oporto, Portugal 90 Portuguese Oncol Inst, Dept Genet, Oporto, Portugal 91 Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA 92 Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA 93 NHGRI, NIH, Bethesda, MD 20892 USA 94 Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10021 USA 95 Med Univ Vienna, Ctr Comprehens Canc, Dept Obstet & Ginecol, Vienna, Austria 96 H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA 97 NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, NIH, Rockville, MD USA 98 Carmel Hosp, Dept Community Med & Epidemiol, Haifa, Israel 99 Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada 100 Univ Hlth Network, Lab Med Program, Toronto, ON, Canada 101 Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON M5G 1X5, Canada 102 Univ Toronto, Dept Mol Genet, Toronto, ON, Canada 103 Ohio State Univ, Dept Mol Virol Immunol & Med Genet, Columbus, OH 43210 USA 104 Aarhus Univ Hosp, Dept Clin Genet, DK-8000 Aarhus, Denmark 105 Odense Univ Hosp, Dept Clin Genet, DK-5000 Odense, Denmark 106 Vejle Hosp, Dept Clin Genet, Vejle, Denmark 107 Rivka Ziv Med Ctr, Inst Oncol, Safed, Israel 108 Sheba Med Ctr, Susanne Levy Gertner Oncogenet Unit, Tel Aviv, Israel 109 Univ Lund Hosp, Dept Clin Genet, S-22185 Lund, Sweden 110 Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden 111 Sahlgrens Univ Hosp, Dept Oncol, Gothenburg, Sweden 112 Linkoping Univ, Dept Clin & Expt Med, Div Clin Genet, Linkoping, Sweden 113 Univ Chicago, Med Ctr, Ctr Clin Canc Genet & Global Hlth, Chicago, IL 60637 USA 114 Univ Calif San Francisco, Dept Med Genet, San Francisco, CA 94143 USA 115 Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Philadelphia, PA 19104 USA 116 Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA 117 Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Womens Canc Program, Los Angeles, CA 90048 USA 118 Univ Erlangen Nurnberg, Erlangen Univ Hosp, Dept Obstet & Gynecol, D-91054 Erlangen, Germany 119 Univ Erlangen Nurnberg, Inst Human Genet, D-91054 Erlangen, Germany 120 Univ Calif Los Angeles, David Geffen Sch Med, Div Hematol & Oncol, Los Angeles, CA 90095 USA 121 Vesalius Res Ctr, VIB, Leuven, Belgium 122 Univ Leuven, Dept Oncol, Lab Translat Genet, Leuven, Belgium 123 Univ Leuven, Dept Oncol, Div Gynecol Oncol, Leuven, Belgium 124 Geisel Sch Med, Dept Community & Family Med, Epidemiol & Biostat Sect, Lebanon, NH USA 125 Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, Seattle, WA 98104 USA 126 Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA 127 German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany 128 Univ Ulm, Dept Obstet & Gynaecol, D-89069 Ulm, Germany 129 Roswell Pk Canc Inst, Dept Canc Prevent & Control, Buffalo, NY 14263 USA 130 Roswell Pk Canc Inst, Dept Gynecol Oncol, Buffalo, NY 14263 USA 131 Univ Hawaii Canc Ctr, Canc Epidemiol Program, Honolulu, HI USA 132 Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA 133 Cedars Sinai Med Ctr, Commun & Populat Hlth Res Inst, Dept Biomed Sci, Los Angeles, CA 90048 USA 134 Univ Jena, Jena Univ Hosp, Dept Gynecol, Jena, Germany 135 Hannover Med Sch, Clin Obstet & Gynaecol, Hannover, Germany 136 Hannover Med Sch, Gynaecol Res Unit, Hannover, Germany 137 Byelorussian Inst Oncol & Med Radiol Aleksandrov, Minsk, Byelarus 138 Univ Helsinki, Cent Hosp, Dept Pathol, Helsinki, Finland 139 Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA 140 Univ Pittsburgh, Sch Med, Dept Obstet Gynecol & Reprod Sci, Pittsburgh, PA USA 141 Univ Pittsburgh, Ovarian Canc Ctr Excellence, Pittsburgh, PA USA 142 Magee Womens Res Inst, Womens Canc Res ProgramInst Canc, Pittsburgh, PA USA 143 Univ Pittsburgh, Inst Canc, Pittsburgh, PA USA 144 Univ Texas Houston, Sch Publ Hlth, Houston, TX USA 145 Dr Horst Schmidt Klin Wiesbaden, Dept Gynecol & Gynecol Oncol, Wiesbaden, Germany 146 Klin Essen Mitte, Dept Gynecol & Gynecol Oncol, Essen, Germany 147 Inst Humangenetik Wiesbaden, Wiesbaden, Germany 148 Kyushu Univ, Fac Med Sci, Dept Prevent Med, Fukuoka 812, Japan 149 Aichi Canc Ctr, Res Inst, Div Epidemiol & Prevent, Nagoya, Aichi 464, Japan 150 Danish Canc Soc, Res Ctr, Dept Virus Lifestyle & Genes, Copenhagen, Denmark 151 Univ Copenhagen, Dept Gynaecol, Copenhagen, Denmark 152 Univ Copenhagen, Herlev Hosp, Dept Pathol, Mol Unit, Copenhagen, Denmark 153 Canc Res Initiat Fdn, Sime Darby Med Ctr, Subang Jaya, Malaysia 154 Univ Malaya, Med Ctr, Dept Obstet & Gynaecol, Kuala Lumpur, Malaysia 155 Univ Malaya, Fac Med, Med Ctr, Canc Res Inst, Kuala Lumpur, Malaysia 156 Univ Kansas, Med Ctr, Biostat & Informat Shared Resource, Kansas City, KS 66103 USA 157 Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Rochester, MN USA 158 Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia 159 Texas So Univ, Coll Pharm & Hlth Sci, Houston, TX 77004 USA 160 Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA 161 Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, New York, NY 10021 USA 162 Duke Univ, Med Ctr, Dept Obstet & Gynecol, Durham, NC 27710 USA 163 Duke Univ, Dept Stat Sci, Durham, NC USA 164 Duke Canc Inst, Canc Control & Populat Sci, Durham, NC USA 165 Duke Univ, Med Ctr, Dept Community & Family Med, Durham, NC 27710 USA 166 Univ Florida, Dept Pathol Immunol & Lab Med, Gainesville, FL USA 167 Univ Florida, Genet Inst, Gainesville, FL USA 168 Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA 169 Harvard Univ, Sch Med, Brigham & Womens Hosp, Obstetr & Gynecol Epidemiol Ctr, Boston, MA 02115 USA 170 Harvard Univ, Sch Med, Brigham & Womens Hosp, Channing Div Network Med, Boston, MA 02115 USA 171 Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA 172 Rutgers Canc Inst New Jersey, Cancer Prevent & Control, New Brunswick, NJ USA 173 Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, Epidemiol Serv, New York, NY 10021 USA 174 Univ Bergen, Dept Clin Med, Ctr Canc Biomarkers, Bergen, Norway 175 Haukeland Hosp, Dept Gynecol & Obstet, N-5021 Bergen, Norway 176 Radboud Univ Nijmegen, Med Ctr, Dept Gynaecol, Nijmegen, Netherlands 177 Ctr Comprehens Canc, Utrecht, Netherlands 178 Radboud Univ Nijmegen, Med Ctr, Dept Hlth Evidence, Nijmegen, Netherlands 179 Radboud Univ Nijmegen, Med Ctr, Dept Urol, Nijmegen, Netherlands 180 British Columbia Canc Agcy, Canadas Michael Smith Genome Sci Ctr, Vancouver, BC V5Z 4E6, Canada 181 Simon Fraser Univ, Dept Biomed Physiol & Kinesiol, Burnaby, BC V5A 1S6, Canada 182 Med Univ S Carolina, Coll Med, Dept Publ Hlth Sci, Charleston, SC 29425 USA 183 Univ New Mexico, Dept Internal Med, Div Epidemiol & Biostat, Albuquerque, NM 87131 USA 184 British Columbia Canc Agcy, Canc Control Res, Vancouver, BC V5Z 4E6, Canada 185 Pomeranian Med Univ, Internat Hereditary Canc Ctr, Dept Genet & Pathol, Clin Opthalmol, Szczecin, Poland 186 NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA 187 Maria Sklodowska Curie Mem Canc Ctr, Inst Oncol, Dept Canc Epidemiol & Prevent, Warsaw, Poland 188 Univ Copenhagen, Dept Pathol, Copenhagen, Denmark 189 Princess Anne Hosp, Wessex Clin Genet Serv, Southampton, Hants, England 190 Univ Glasgow, Wolfson Wohl Canc Res Ctr, Beatson Inst Canc Res, Inst Canc Sci, Glasgow, Lanark, Scotland 191 Beatson West Scotland, Ctr Canc, Canc Res UK Clin, Trials Unit, Glasgow, Lanark, Scotland 192 Glasgow Royal Infirm, Dept Gynecol Oncol, Glasgow G4 0SF, Lanark, Scotland 193 Stanford Univ, Sch Med, Dept Hlth Res & Policy Epidemiol, Stanford, CA 94305 USA 194 Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA 195 Shanghai Canc Inst, Shanghai, Peoples R China 196 Univ Toronto, Fac Med, Dept Obstet & Gynaecol, Toronto, ON, Canada 197 Princess Margaret Hosp, Dept Gynecol Oncol, Toronto, ON M4X 1K9, Canada 198 Yale Sch Publ Hlth, Dept Chron Dis Epidemiol, New Haven, CT USA 199 Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Prosserman Ctr Hlth Res, Toronto, ON M5G 1X5, Canada 200 Univ Toronto, Womens Coll Res Inst, Toronto, ON, Canada 201 H Lee Moffitt Canc Ctr & Res Inst, Dept Biostat, Tampa, FL USA 202 Univ Calif Irvine, Dept Epidemiol, Irvine, CA USA 203 UCL, Elizabeth Garrett Anderson EGA Inst Womens Hlth, London, England 204 Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10021 USA 205 Maria Sklodowska Curie Mem Canc Ctr, Inst Oncol, Dept Pathol, Warsaw, Poland 206 Med Univ Warsaw, Fac Med 2, Dept Obstet Gynecol & Oncol, Warsaw, Poland 207 Brodnowski Hosp, Warsaw, Poland

مصطلحات موضوعية: Eggjastokkar, Krabbamein, Arfgengi, Adolescent, Adult, Alleles, BRCA1 Protein, BRCA2 Protein, Female, Genes, Reporter, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Heterozygote, Humans, Mutation, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Risk, Young Adult

العلاقة: info:eu-repo/grantAgreement/EC/FP7/22317; info:eu-repo/grantAgreement/EC/FP7/223175; http://dx.doi.orgTest/ 10.1038/ng.3185; http://www.nature.com/ng/journal/v47/n2/pdf/ng.3185.pdfTest; Nat. Genet. 2015, 47 (2):164-71; http://hdl.handle.net/2336/558549Test; Nature genetics

الإتاحة: https://doi.org/10.1038/ng.3185Test
http://hdl.handle.net/2336/558549Test

المؤلفون: Rafnar, Thorunn, Gudbjartsson, Daniel F, Sulem, Patrick, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Besenbacher, Soren, Lundin, Pär, Stacey, Simon N, Gudmundsson, Julius, Magnusson, Olafur T, le Roux, Louise, Orlygsdottir, Gudbjorg, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Gylfason, Arnaldur, Tryggvadottir, Laufey, Jonasson, Jon G, de Juan, Ana, Ortega, Eugenia, Ramon-Cajal, Jose M, García-Prats, Maria D, Mayordomo, Carlos, Panadero, Angeles, Rivera, Fernando, Aben, Katja K H, van Altena, Anne M, Massuger, Leon F A G, Aavikko, Mervi, Kujala, Paula M, Staff, Synnöve, Aaltonen, Lauri A, Olafsdottir, Kristrun, Bjornsson, Johannes, Kong, Augustine, Salvarsdottir, Anna, Saemundsson, Hafsteinn, Olafsson, Karl, Benediktsdottir, Kristrun R, Gulcher, Jeffrey, Masson, Gisli, Kiemeney, Lambertus A, Mayordomo, Jose I, Thorsteinsdottir, Unnur, Stefansson, Kari

المساهمون: deCODE genetics, Reykjavik, Iceland. thorunn.rafnar@decode.is

مصطلحات موضوعية: DNA-Binding Proteins, Female, Humans, Mutation, Ovarian Neoplasms, Polymorphism, Single Nucleotide, RNA Helicases

العلاقة: info:eu-repo/grantAgreement/EC/FP7/ 218071; http://dx.doi.org/10.1038/ng.955Test; Nat. Genet. 2011, 43(11):1104-7; http://hdl.handle.net/2336/228034Test; Nature genetics

الإتاحة: https://doi.org/10.1038/ng.955Test
http://hdl.handle.net/2336/228034Test

المؤلفون: Phelan, Catherine M, Kuchenbaecker, Karoline B, Tyrer, Jonathan P, Kar, Siddhartha P, Lawrenson, Kate, Winham, Stacey J, Dennis, Joe, Pirie, Ailith, Riggan, Marjorie J, Chornokur, Ganna, Earp, Madalene A, Lyra, Paulo C, Lee, Janet M, Coetzee, Simon, Beesley, Jonathan, McGuffog, Lesley, Soucy, Penny, Dicks, Ed, Lee, Andrew, Barrowdale, Daniel, Lecarpentier, Julie, Leslie, Goska, Aalfs, Cora M, Aben, Katja K H, Adams, Marcia, Adlard, Julian, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia, Aravantinos, Gerasimos, Arnold, Norbert, Arun, Banu K, Arver, Brita, Azzollini, Jacopo, Balmaña, Judith, Banerjee, Susana N, Barjhoux, Laure, Barkardottir, Rosa B, Bean, Yukie, Beckmann, Matthias W, Beeghly-Fadiel, Alicia, Benitez, Javier, Bermisheva, Marina, Bernardini, Marcus Q, Birrer, Michael J, Bjorge, Line, Black, Amanda, Blankstein, Kenneth, Blok, Marinus J, Bodelon, Clara, Bogdanova, Natalia, Bojesen, Anders, Bonanni, Bernardo, Borg, Åke, Bradbury, Angela R, Brenton, James D, Brewer, Carole, Brinton, Louise, Broberg, Per, Brooks-Wilson, Angela, Bruinsma, Fiona, Brunet, Joan, Buecher, Bruno, Butzow, Ralf, Buys, Saundra S, Caldes, Trinidad, Caligo, Maria A, Campbell, Ian, Cannioto, Rikki, Carney, Michael E, Cescon, Terence, Chan, Salina B, Chang-Claude, Jenny, Chanock, Stephen, Chen, Xiao Qing, Chiew, Yoke-Eng, Chiquette, Jocelyne, Chung, Wendy K, Claes, Kathleen B M, Conner, Thomas, Cook, Linda S, Cook, Jackie, Cramer, Daniel W, Cunningham, Julie M, D'Aloisio, Aimee A, Daly, Mary B, Damiola, Francesca, Damirovna, Sakaeva Dina, Dansonka-Mieszkowska, Agnieszka, Dao, Fanny, Davidson, Rosemarie, DeFazio, Anna, Delnatte, Capucine, Doheny, Kimberly F, Diez, Orland, Ding, Yuan Chun, Doherty, Jennifer Anne, Domchek, Susan M, Dorfling, Cecilia M, Dörk, Thilo, Dossus, Laure, Duran, Mercedes, Dürst, Matthias, Dworniczak, Bernd, Eccles, Diana, Edwards, Todd, Eeles, Ros, Eilber, Ursula, Ejlertsen, Bent, Ekici, Arif B, Ellis, Steve, Elvira, Mingajeva, Eng, Kevin H, Engel, Christoph, Evans, D Gareth, Fasching, Peter A, Ferguson, Sarah, Ferrer, Sandra Fert, Flanagan, James M, Fogarty, Zachary C, Fortner, Renée T, Fostira, Florentia, Foulkes, William D, Fountzilas, George, Fridley, Brooke L, Friebel, Tara M, Friedman, Eitan, Frost, Debra, Ganz, Patricia A, Garber, Judy, García, María J, Garcia-Barberan, Vanesa, Gehrig, Andrea, Gentry-Maharaj, Aleksandra, Gerdes, Anne-Marie, Giles, Graham G, Glasspool, Rosalind, Glendon, Gord, Godwin, Andrew K, Goldgar, David E, Goranova, Teodora, Gore, Martin, Greene, Mark H, Gronwald, Jacek, Gruber, Stephen, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hamann, Ute, Hansen, Thomas V O, Harrington, Patricia A, Harris, Holly R, Hauke, Jan, Hein, Alexander, Henderson, Alex, Hildebrandt, Michelle A T, Hillemanns, Peter, Hodgson, Shirley, Høgdall, Claus K, Høgdall, Estrid, Hogervorst, Frans B L, Holland, Helene, Hooning, Maartje J, Hosking, Karen, Huang, Ruea-Yea, Hulick, Peter J, Hung, Jillian, Hunter, David J, Huntsman, David G, Huzarski, Tomasz, Imyanitov, Evgeny N, Isaacs, Claudine, Iversen, Edwin S, Izatt, Louise, Izquierdo, Angel, Jakubowska, Anna, James, Paul, Janavicius, Ramunas, Jernetz, Mats, Jensen, Allan, Jensen, Uffe Birk, John, Esther M, Johnatty, Sharon, Jones, Michael E, Kannisto, Päivi, Karlan, Beth Y, Karnezis, Anthony, Kast, Karin, Kennedy, Catherine J, Khusnutdinova, Elza, Kiemeney, Lambertus A, Kiiski, Johanna I, Kim, Sung-Won, Kjaer, Susanne K, Köbel, Martin, Kopperud, Reidun K, Kruse, Torben A, Kupryjanczyk, Jolanta, Kwong, Ava, Laitman, Yael, Lambrechts, Diether, Larrañaga, Nerea, Larson, Melissa C, Lazaro, Conxi, Le, Nhu D, Le Marchand, Loic, Lee, Jong Won, Lele, Shashikant B, Leminen, Arto, Leroux, Dominique, Lester, Jenny, Lesueur, Fabienne, Levine, Douglas A, Liang, Dong, Liebrich, Clemens, Lilyquist, Jenna, Lipworth, Loren, Lissowska, Jolanta, Lu, Karen H, Lubinński, Jan, Luccarini, Craig, Lundvall, Lene, Mai, Phuong L, Mendoza-Fandiño, Gustavo, Manoukian, Siranoush, Massuger, Leon F A G, May, Taymaa, Mazoyer, Sylvie, McAlpine, Jessica N, McGuire, Valerie, McLaughlin, John R, McNeish, Iain, Meijers-Heijboer, Hanne, Meindl, Alfons, Menon, Usha, Mensenkamp, Arjen R, Merritt, Melissa A, Milne, Roger L, Mitchell, Gillian, Modugno, Francesmary, Moes-Sosnowska, Joanna, Moffitt, Melissa, Montagna, Marco, Moysich, Kirsten B, Mulligan, Anna Marie, Musinsky, Jacob, Nathanson, Katherine L, Nedergaard, Lotte, Ness, Roberta B, Neuhausen, Susan L, Nevanlinna, Heli, Niederacher, Dieter, Nussbaum, Robert L, Odunsi, Kunle, Olah, Edith, Olopade, Olufunmilayo I, Olsson, Håkan, Olswold, Curtis, O'Malley, David M, Ong, Kai-Ren, Onland-Moret, N Charlotte, Orr, Nicholas, Orsulic, Sandra, Osorio, Ana, Palli, Domenico, Papi, Laura, Park-Simon, Tjoung-Won, Paul, James, Pearce, Celeste L, Pedersen, Inge Søkilde, Peeters, Petra H M, Peissel, Bernard, Peixoto, Ana, Pejovic, Tanja, Pelttari, Liisa M, Permuth, Jennifer B, Peterlongo, Paolo, Pezzani, Lidia, Pfeiler, Georg, Phillips, Kelly-Anne, Piedmonte, Marion, Pike, Malcolm C, Piskorz, Anna M, Poblete, Samantha R, Pocza, Timea, Poole, Elizabeth M, Poppe, Bruce, Porteous, Mary E, Prieur, Fabienne, Prokofyeva, Darya, Pugh, Elizabeth, Pujana, Miquel Angel, Pujol, Pascal, Radice, Paolo, Rantala, Johanna, Rappaport-Fuerhauser, Christine, Rennert, Gad, Rhiem, Kerstin, Rice, Patricia, Richardson, Andrea, Robson, Mark, Rodriguez, Gustavo C, Rodríguez-Antona, Cristina, Romm, Jane, Rookus, Matti A, Rossing, Mary Anne, Rothstein, Joseph H, Rudolph, Anja, Runnebaum, Ingo B, Salvesen, Helga B, Sandler, Dale P, Schoemaker, Minouk J, Senter, Leigha, Setiawan, V Wendy, Severi, Gianluca, Sharma, Priyanka, Shelford, Tameka, Siddiqui, Nadeem, Side, Lucy E, Sieh, Weiva, Singer, Christian F, Sobol, Hagay, Song, Honglin, Southey, Melissa C, Spurdle, Amanda B, Stadler, Zsofia, Steinemann, Doris, Stoppa-Lyonnet, Dominique, Sucheston-Campbell, Lara E, Sukiennicki, Grzegorz, Sutphen, Rebecca, Sutter, Christian, Swerdlow, Anthony J, Szabo, Csilla I, Szafron, Lukasz, Tan, Yen Y, Taylor, Jack A, Tea, Muy-Kheng, Teixeira, Manuel R, Teo, Soo-Hwang, Terry, Kathryn L, Thompson, Pamela J, Thomsen, Liv Cecilie Vestrheim, Thull, Darcy L, Tihomirova, Laima, Tinker, Anna V, Tischkowitz, Marc, Tognazzo, Silvia, Toland, Amanda Ewart, Tone, Alicia, Trabert, Britton, Travis, Ruth C, Trichopoulou, Antonia, Tung, Nadine, Tworoger, Shelley S, van Altena, Anne M, Van Den Berg, David, van der Hout, Annemarie H, van der Luijt, Rob B, Van Heetvelde, Mattias, Van Nieuwenhuysen, Els, van Rensburg, Elizabeth J, Vanderstichele, Adriaan, Varon-Mateeva, Raymonda, Vega, Ana, Edwards, Digna Velez, Vergote, Ignace, Vierkant, Robert A, Vijai, Joseph, Vratimos, Athanassios, Walker, Lisa, Walsh, Christine, Wand, Dorothea, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Webb, Penelope M, Weinberg, Clarice R, Weitzel, Jeffrey N, Wentzensen, Nicolas, Whittemore, Alice S, Wijnen, Juul T, Wilkens, Lynne R, Wolk, Alicja, Woo, Michelle, Wu, Xifeng, Wu, Anna H, Yang, Hannah, Yannoukakos, Drakoulis, Ziogas, Argyrios, Zorn, Kristin K, Narod, Steven A, Easton, Douglas F, Amos, Christopher I, Schildkraut, Joellen M, Ramus, Susan J, Ottini, Laura, Goodman, Marc T, Park, Sue K, Kelemen, Linda E, Risch, Harvey A, Thomassen, Mads, Offit, Kenneth, Simard, Jacques, Schmutzler, Rita Katharina, Hazelett, Dennis, Monteiro, Alvaro N, Couch, Fergus J, Berchuck, Andrew, Chenevix-Trench, Georgia, Goode, Ellen L, Sellers, Thomas A, Gayther, Simon A, Antoniou, Antonis C, Pharoah, Paul D P

المساهمون: Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA. 2 Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, Florida, USA. 3 Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, UK. 4 Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK. 5 Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK. 6 Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. 7 Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA. 8 Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA. 9 Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA. 10 Center for Bioinformatics and Functional Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. 11 Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. 12 Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. 13 Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada. 14 Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands. 15 Radboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands. 16 Netherlands Comprehensive Cancer Organisation, Utrecht, the Netherlands. 17 Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. 18 Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, UK. 19 Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. 20 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. 21 Genetic Epidemiology Research Institute, UCI Center for Cancer Genetics Research and Prevention, School of Medicine, University of California-Irvine, Irvine, California, USA. 22 Department of Epidemiology, University of California-Irvine, Irvine, California, USA. 23 N.N. Alexandrov National Cancer Centre of Belarus, Minsk, Belarus. 24 'Agii Anargiri' Cancer Hospital, Athens, Greece. 25 Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian Albrechts University Kiel, Kiel, Germany. 26 Department of Breast Medical Oncology and Clinical Cancer Genetics Program, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 27 Department of Oncology and Pathology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden. 28 Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy. 29 Department of Medical Oncology, University Hospital, Vall d'Hebron, Barcelona, Spain. 30 Gynaecology Unit, Royal Marsden Hospital, London, UK. 31 Bâtiment Cheney D, Centre Léon Bérard, Lyon, France. 32 Laboratory of Cell Biology, Department of Pathology, Landspitali, Reykjavik, Iceland. 33 BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 34 Department of Gynecologic Oncology, Oregon Health &Science University, Portland, Oregon, USA. 35 Knight Cancer Institute, Oregon Health &Science University, Portland, Oregon, USA. 36 Department of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany. 37 Division of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA. 38 Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt Medical School, Nashville, Tennessee, USA. 39 Institute for Medicine and Public Health, Vanderbilt School of Medicine, Nashville, Tennessee, USA. 40 Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tennessee, USA. 41 Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain. 42 Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. 43 Institute of Biochemistry and Genetics, Ufa Science Center, Russian Academy of Sciences, Ufa, Russian Federation. 44 Division of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada. 45 Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA. 46 Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway. 47 Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway. 48 Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA. 49 Clinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA. 50 Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands. 51 Radiation Oncology Research Unit, Hannover Medical School, Hannover, Germany. 52 Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. 53 Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia (IEO), Milan, Italy. 54 Department of Oncology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden. 55 Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA. 56 Cancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK. 57 Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, UK. 58 Department of Cancer Epidemiology, University Hospital, Lund, Lund University, Lund, Sweden. 59 Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada. 60 Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia. 61 Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain. 62 Service de Génétique Oncologique, Institut Curie, Paris, France. 63 Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 64 Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA. 65 Molecular Oncology Laboratory, Hospital Clínico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain. 66 Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa, Italy. 67 Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. 68 Department of Pathology, University of Melbourne, Parkville, Victoria, Australia. 69 Cancer Pathology and Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA. 70 Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA. 71 Cancer Risk Program, University of California, San Francisco, San Francisco, California, USA. 72 Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. 73 University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 74 Centre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia. 75 Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia. 76 Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Centre de Recherche FRSQ du Centre Hospitalier Affilié Universitaire de Québec, Quebec City, Quebec, Canada. 77 Departments of Pediatrics and Medicine, Columbia University, New York, New York, USA. 78 Center for Medical Genetics, Ghent University, Ghent, Belgium. 79 Division of Epidemiology, Biostatistics and Preventative Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA. 80 Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK. 81 Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. 82 Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA. 83 Social &Scientific Systems, Inc., Durham, North Carolina, USA. 84 Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA. 85 Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation. 86 Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland. 87 Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA. 88 Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, UK. 89 Unité d'Oncogénétique, ICO-Centre René Gauducheau, Nantes, France. 90 Oncogenetics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain. 91 Clinical and Molecular Genetics Area, Vall d'Hebron University Hospital. Barcelona, Spain. 92 Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA. 93 Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. 94 Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria, South Africa. 95 Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. 96 Nutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France. 97 Institute of Biology and Molecular Genetics, Universidad de Valladolid (IBGM-UVA), Valladolid, Spain. 98 Department of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany. 99 Institute of Human Genetics, Münster, Germany. 100 University of Southampton Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, UK. 101 Oncogenetics Team, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. 102 Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 103 Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany. 104 Department of Biostatistics and Bioinformatics, Roswell Park Institute, Buffalo, New York, USA. 105 Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. 106 Genomic Medicine, Manchester Academic Health Sciences Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK. 107 Division of Hematology and Oncology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, California, USA. 108 Laboratoire de Génétique Chromosomique, Hôtel Dieu Centre Hospitalier, Chambéry, France. 109 Department of Surgery and Cancer, Imperial College London, London, UK. 110 Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens, Greece. 111 Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada. 112 Department of Medical Oncology, Papageorgiou, Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece. 113 Biostatistics and Informatics Shared Resource, University of Kansas Medical Center, Kansas City, Kansas, USA. 114 Harvard T.H. Chan School of Public Health and Dana-Farber Cancer Institute, Boston, Massachusetts, USA. 115 Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel. 116 Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. 117 Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, UCLA Schools of Medicine and Public Health, Los Angeles, California, USA. 118 Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. 119 Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany. 120 Women's Cancer, Institute for Women's Health, University College London, London, UK. 121 Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 122 Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia. 123 Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. 124 Beatson West of Scotland Cancer Centre, Glasgow, UK. 125 Ontario Cancer Genetics Network: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. 126 Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA. 127 Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah, USA. 128 Department of Medicine, Royal Marsden Hospital, London, UK. 129 Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA. 130 Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. 131 Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. 132 Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany. 133 Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA. 134 Division of Nutritional Epidemiology, Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. 135 Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany. 136 Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. 137 Institute of Genetic Medicine, Centre for Life, Newcastle-upon-Tyne Hospitals NHS Trust, Newcastle-upon-Tyne, UK. 138 Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 139 Clinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany. 140 Medical Genetics Unit, St George's University of London, London, UK. 141 Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. 142 Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. 143 Molecular Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark. 144 Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands. 145 Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands. 146 Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York, USA. 147 Center for Medical Genetics, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Evanston, Illinois, USA. 148 Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. 149 Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. 150 British Columbia Cancer Agency, Vancouver, British Columbia, Canada. 151 N.N. Petrov Institute of Oncology, St. Petersburg, Russian Federation. 152 Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. 153 Department of Statistical Science, Duke University, Durham, North Carolina, USA. 154 Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK. 155 Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. 156 Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia. 157 Department of Molecular and Regenerative Medicine, Hematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania. 158 State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania. 159 Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden. 160 Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark. 161 Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, USA. 162 Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK. 163 Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany. 164 Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. 165 Department of Surgery, Breast Care Center, Daerim St. Mary's Hospital, Seoul, Republic of Korea. 166 Department of Pathology, University of Calgary, Calgary, Alberta, Canada. 167 Department of Clinical Genetics, Odense University Hospital, Odense, Denmark. 168 Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong. 169 Department of Surgery, University of Hong Kong, Hong Kong. 170 Cancer Genetics Center and Department of Surgery, Hong Kong Sanatorium and Hospital, Hong Kong. 171 Vesalius Research Center, VIB, Leuven, Belgium. 172 Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium. 173 Public Health Division of Gipuzkoa, Regional Government of the Basque Country, Donostia-San Sebastian, Spain. 174 CIBER of Epidemiology and Public Health, Madrid, Spain. 175 Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain. 176 Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada. 177 Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA. 178 Department of Surgery, Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea. 179 Department of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA. 180 Département de Génétique, Centre Hospitalier Universitaire de Grenoble, Grenoble, France. 181 Institut Curie, PSL Research Unviersity and INSERM U900, Paris, France. 182 Mines Paris Tech, Fontainebleau, France. 183 College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA. 184 Cancer Center Wolfsburg, Clinics of Gynaecology, Wolfsburg, Germany. 185 Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA. 186 Department of Cancer Epidemiology and Prevention, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland. 187 Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 188 Juliane Marie Centre, Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. 189 INSERM U1052, CNRS UMR 5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Centre Léon Bérard, Lyon, France. 190 Ovarian Cancer Research (OVCARE) Program-Gynecologic Tissue Bank, Vancouver General Hospital and BC Cancer Agency, Vancouver, British Columbia, Canada. 191 Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA. 192 Public Health Ontario, Toronto, Ontario, Canada. 193 Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research, Glasgow, UK. 194 Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands. 195 Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany. 196 Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands. 197 Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. 198 Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. 199 Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA. 200 Ovarian Cancer Center of Excellence, Womens Cancer Research Program, Magee-Womens Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA. 201 Department of Obstetrics and Gynecology, Oregon Health &Science University, Portland, Oregon, USA. 202 Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy. 203 Department of Laboratory Medicine and Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada. 204 Clinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. 205 Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. 206 University of Texas School of Public Health, Houston, Texas, USA. 207 Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. 208 Invitae Corporation, San Francisco, California, USA. 209 Department of Medicine, University of California, San Francisco, San Francisco, California, USA. 210 Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. 211 Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois, USA. 212 Department of Oncology, Lund University Hospital, Lund, Sweden. 213 Department of Obstetrics and Gynecology, Ohio State University and the James Cancer Center, Columbus, Ohio, USA. 214 West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK. 215 Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. 216 Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, UK. 217 Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Florence, Italy. 218 Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy. 219 Cancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. 220 Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. 221 Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark. 222 Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. 223 IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. 224 Department of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria. 225 Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia. 226 NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York, USA. 227 Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA. 228 Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. 229 South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK. 230 Service de Génétique Clinique Chromosomique et Moléculaire, Centre Hospitalier Universitaire de St Etienne, St Etienne, France. 231 Translational Research Laboratory, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain. 232 Unité d'Oncogénétique, Centre Hospitalier Universitaire Arnaud de Villeneuve, Montpellier, France. 233 Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy. 234 Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden. 235 Clalit National Israeli Cancer Control Center, Haifa, Israel. 236 Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine, Haifa, Israel. 237 Department of Pathology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. 238 Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. 239 Division of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA. 240 Hereditary Endocrine Cancer Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain. 241 Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands. 242 Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. 243 Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA. 244 Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA. 245 Facultés de Médecin, Université Paris-Sud, Villejuif, France. 246 Institut Gustave Roussy, Villejuif, France. 247 Human Genetics Foundation (HuGeF), Turin, Italy. 248 Facultés de Médecin, Université Paris-Saclay, Paris, France. 249 Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA. 250 Department of Gynaecological Oncology, Glasgow Royal Infirmary, Glasgow, UK. 251 North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK. 252 Département Oncologie Génétique, Institut Paoli-Calmettes, Marseille, France. 253 Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Victoria, Australia. 254 Institute of Human Genetics, Hannover Medical School, Hannover, Germany. 255 Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA. 256 Epidemiology Center, College of Medicine, University of South Florida, Tampa, Florida, USA. 257 Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. 258 Division of Breast Cancer Research, Institute of Cancer Research, London, UK. 259 National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA. 260 Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal. 261 Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia. 262 University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia. 263 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. 264 Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. 265 Magee-Womens Hospital of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. 266 Latvian Biomedical Research and Study Centre, Riga, Latvia. 267 Ovarian Cancer Research (OVCARE) Program-Cheryl Brown Ovarian Cancer Outcomes Unit (CBOCOU), BC Cancer Agency, Vancouver, British Columbia, Canada. 268 Department of Medical Genetics, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, UK. 269 Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA. 270 Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. 271 Hellenic Health Foundation, Athens, Greece. 272 WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece. 273 Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA. 274 Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, the Netherlands. 275 Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. 276 Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands. 277 Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium. 278 Institute of Medical and Human Genetics, Charité Universitätsmedizin, Campus Virchov Klinikum, Berlin, Germany. 279 Fundación Pública Galega de Medicina Xenómica, Servizo Galego de Saúde (SERGAS), Instituto de Investigación Sanitaria (IDIS), Santiago de Compostela, Spain. 280 Grupo de Medicina Xenómica, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universidade de Santiago de Compostela (USC), Santiago de Compostela, Spain. 281 Vanderbilt Genetics Institute and Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. 282 Oxford Regional Genetics Service, Churchill Hospital, Oxford, UK. 283 Institute of Human Genetics, University Hospital, Leipzig, Germany. 284 Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany. 285 Population Health Department, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia. 286 Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA. 287 Clinical Cancer Genetics, City of Hope, Duarte, California, USA. 288 Department of Data Management Science, Stanford University School of Medicine, Stanford, California, USA. 289 Departments of Human Genetics and Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. 290 Women's College Research Institute, University of Toronto, Toronto, Ontario, Canada. 291 Center for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA. 292 Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA. 293 School of Women's and Children's Health, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia. 294 Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia. 295 Department of Molecular Medicine, University La Sapienza, Rome, Italy. 296 Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA. 297 Department of Preventive Medicine, College of Medicine, Seoul National University, Seoul, Republic of Korea. 298 Seoul National University Cancer Research Institute, Seoul, Republic of Korea. 299 Department of Biomedical Science, Graduate School, Seoul National University, Seoul, Republic of Korea. 300 Department of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA. 301 Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA. 302 Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.

مصطلحات موضوعية: Krabbamein, Eggjastokkar, NAF12, Ovarian Neoplasms, Epithelial Cells

العلاقة: https://www.nature.com/ng/journal/v49/n5/pdf/ng.3826.pdfTest; Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 2017, 49 (5):680-691 Nat. Genet.; http://hdl.handle.net/2336/620225Test; Nature genetics

الإتاحة: https://doi.org/10.1038/ng.3826Test
http://hdl.handle.net/2336/620225Test

المؤلفون: Hollestelle, Antoinette, van der Baan, Frederieke H, Berchuck, Andrew, Johnatty, Sharon E, Aben, Katja K, Agnarsson, Bjarni A, Aittomäki, Kristiina, Alducci, Elisa, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, van Altena, Anne M, Van Asperen, C J, van den Berg, David, van den Ouweland, Ans M W, van Doorn, Helena C, Goodman, Marc T, Van Nieuwenhuysen, Els, van Rensburg, Elizabeth J, Vergote, Ignace, Mai, Phuong L, Poppe, Bruce, Bojesen, Anders, Verhoef, Senno, Vierkant, Robert A, Vijai, Joseph, Vitonis, Allison F, von Wachenfeldt, Anna, Walsh, Christine, Gore, Martin, Wang, Qin, Wang-Gohrke, Shan, Pylkäs, Katri, Balleine, Rosemary, Wappenschmidt, Barbara, Weischer, Maren, Bojesen, Stig E, Weitzel, Jeffrey N, Weltens, Caroline, Wentzensen, Nicolas, Whittemore, Alice S, Wilkens, Lynne R, Greene, Mark H, Radice, Paolo, Winqvist, Robert, Fridley, Brooke L, Wu, Anna H, Wu, Xifeng, Yang, Hannah P, Zaffaroni, Daniela, Bolla, Manjeet K, Pilar Zamora, M, Zheng, Wei, Ziogas, Argyrios, Ramus, Susan J, Chenevix-Trench, Georgia, Grip, Mervi, Mannermaa, Arto, Pharoah, Paul D P, Rookus, Matti A, Hooning, Maartje J, Goode, Ellen L, Bonanni, Bernardo, Brand, Judith S, Brauch, Hiltrud, Rebbeck, Timothy R, Brenner, Hermann, Brinton, Louise, Brooks-Wilson, Angela, Margolin, Sara, Gronwald, Jacek, Bruinsma, Fiona, Brunet, Joan, Brüning, Thomas, Budzilowska, Agnieszka, Bunker, Clareann H, Berger, Andreas, Burwinkel, Barbara, Butzow, Ralf, Buys, Saundra S, Caligo, Maria A, Mariette, Frederique, Campbell, Ian, Gschwantler Kaulich, Daphne, Carter, Jonathan, Chang-Claude, Jenny, Chanock, Stephen J, Reed, Malcolm W R, Claes, Kathleen B M, Collée, J Margriet, Cook, Linda S, Couch, Fergus J, Cox, Angela, Marme, Frederik, Cramer, Daniel, Cross, Simon S, Apicella, Carmel, Cunningham, Julie M, Rennert, Gad, Cybulski, Cezary, Czene, Kamila, Damiola, Francesca, Dansonka-Mieszkowska, Agnieszka, Darabi, Hatef, de la Hoya, Miguel, Martens, John W M, deFazio, Anna, Dennis, Joseph, Devilee, Peter, Risch, Harvey A, Guénel, Pascal, Dicks, Ed M, Diez, Orland, Doherty, Jennifer A, Domchek, Susan M, Dorfling, Cecilia M, Dörk, Thilo, Massuger, Leon F A G, Silva, Isabel Dos Santos, du Bois, Andreas, Gentry-Maharaj, Aleksandra, Dumont, Martine, Dunning, Alison M, Guzman, Starr R, Duran, Mercedes, Easton, Douglas F, Eccles, Diana, Edwards, Robert P, Ehrencrona, Hans, Maugard, Christine, Ejlertsen, Bent, Lindblom, Annika, Ekici, Arif B, Ellis, Steve D, Engel, Christoph, Eriksson, Mikael, Haeberle, Lothar, Fasching, Peter A, Feliubadalo, Lidia, Figueroa, Jonine, Flesch-Janys, Dieter, Mazoyer, Sylvie, Robson, Mark, Fletcher, Olivia, Fontaine, Annette, Fortuzzi, Stefano, Fostira, Florentia, Haiman, Christopher A, Hall, Per, Halverson, Sandra L, Hamann, Ute, Hansen, Thomas V O, Harter, Philipp, Rodriguez, Gustavo C, McGuffog, Lesley, Hartikainen, Jaana M, Arndt, Volker, Healey, Sue, Hein, Alexander, Heitz, Florian, Henderson, Brian E, Herzog, Josef, T Hildebrandt, Michelle A, Høgdall, Claus K, Romero, Atocha, Høgdall, Estrid, McGuire, Valerie, Hogervorst, Frans B L, Hopper, John L, Arnold, Norbert, Humphreys, Keith, Huzarski, Tomasz, Imyanitov, Evgeny N, Isaacs, Claudine, Jakubowska, Anna, Rossing, Mary Anne, Janavicius, Ramunas, Jaworska, Katarzyna, Friebel, Tara, Jensen, Allan, Jensen, Uffe Birk, Johnson, Nichola, Arun, Banu K, Jukkola-Vuorinen, Arja, Kabisch, Maria, Karlan, Beth Y, Rothstein, Joseph H, Kataja, Vesa, Kauff, Noah, Kelemen, Linda E, Bandera, Elisa V, Kerin, Michael J, Kiemeney, Lambertus A, Kjaer, Susanne K, Knight, Julia A, Arver, Brita, Knol-Bout, Jacoba P, Rudolph, Anja, Konstantopoulou, Irene, Kosma, Veli-Matti, Krakstad, Camilla, Kristensen, Vessela, McLean, Catriona, Kuchenbaecker, Karoline B, Kupryjanczyk, Jolanta, Laitman, Yael, Lambrechts, Diether, Lambrechts, Sandrina, Runnebaum, Ingo, Ashworth, Alan, Larson, Melissa C, Lasa, Adriana, Laurent-Puig, Pierre, Lazaro, Conxi, McNeish, Iain, Le, Nhu D, Le Marchand, Loic, Leminen, Arto, Lester, Jenny, Berger, Raanan, Levine, Douglas A, Li, Jingmei, Baglietto, Laura, Liang, Dong, Meindl, Alfons, Menegaux, Florence, Menéndez, Primitiva, Menkiszak, Janusz, Menon, Usha, Mensenkamp, Arjen R, Salani, Ritu, Miller, Nicola, Friedman, Eitan, Milne, Roger L, Barrowdale, Daniel, Modugno, Francesmary, Montagna, Marco, Moysich, Kirsten B, Müller, Heiko, Mulligan, Anna Marie, Muranen, Taru A, Salvesen, Helga B, Narod, Steven A, Nathanson, Katherine L, Friel, Grace, Ness, Roberta B, Neuhausen, Susan L, Bean, Yukie T, Nevanlinna, Heli, Neven, Patrick, Nielsen, Finn C, Nielsen, Sune F, Lindor, Noralane, Nordestgaard, Børge G, Nussbaum, Robert L, Odunsi, Kunle, Frost, Debra, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Beckmann, Lars, Olson, Janet E, Olson, Sara H, Gerdes, Anne-Marie, Oosterwijk, Jan C, Orlow, Irene, Orr, Nick, Orsulic, Sandra, Garber, Judy, Osorio, Ana, Ottini, Laura, Paul, James, Pearce, Celeste L, Beckmann, Matthias W, Sawyer, Elinor J, Pedersen, Inge Sokilde, Peissel, Bernard, Pejovic, Tanja, Pelttari, Liisa M, Perkins, Jo, García-Closas, Montserrat, Permuth-Wey, Jenny, Peterlongo, Paolo, Peto, Julian, Phelan, Catherine M, Schildkraut, Joellen M, Phillips, Kelly-Anne, Benitez, Javier, Piedmonte, Marion, Pike, Malcolm C, Platte, Radka, Plisiecka-Halasa, Joanna, Gayther, Simon A, Poole, Elizabeth M, Schmidt, Marjanka K, Schmutzler, Rita K, Schneeweiss, Andreas, Schoemaker, Minouk J, Schrauder, Michael G, Schumacher, Fredrick, Beuselinck, Benoit, Lissowska, Jolanta, Schwaab, Ira, Antoniou, Antonis C, Scuvera, Giulietta, Sellers, Thomas A, Severi, Gianluca, Seynaeve, Caroline M, Shah, Mitul, Shrubsole, Martha, Siddiqui, Nadeem, Sieh, Weiva, Long, Jirong, Simard, Jacques, Bisogna, Maria, Giles, Graham G, Singer, Christian F, Sinilnikova, Olga M, Smeets, Dominiek, Sohn, Christof, Soller, Maria, Song, Honglin, Soucy, Penny, Lu, Karen H, Southey, Melissa C, Stegmaier, Christa, Stoppa-Lyonnet, Dominique, Glasspool, Rosalind, Bjorge, Line, Sucheston, Lara, Swerdlow, Anthony, Tangen, Ingvild L, Tea, Muy-Kheng, Teixeira, Manuel R, Lubinski, Jan, Terry, Kathryn L, Terry, Mary Beth, Thomassen, Mads, Thompson, Pamela J, Glendon, Gord, Tihomirova, Laima, Blomqvist, Carl, Tischkowitz, Marc, Toland, Amanda Ewart, Tollenaar, Rob A E M, Lundvall, Lene, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Tsimiklis, Helen, Tung, Nadine, Godwin, Andrew K, Tworoger, Shelley S, Tyrer, Jonathan P, Bogdanova, Natalia V, Vachon, Celine M, Lurie, Galina, Van 't Veer, Laura J

مصطلحات موضوعية: Brjóstakrabbamein, Arfgengi, Eggjastokkar, Krabbamein, PTT12, Breast Neoplasms, Treatment Outcome, Genetic Association Studies, Proto-Oncogene Proteins p21(ras), Ovarian Neoplasms

العلاقة: info:eu-repo/grantAgreement/EC/FP7/223175; http://dx.doi.orgTest/ 10.1016/j.ygyno.2015.04.034; No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. 2016, 141 (2):386-401 Gynecol. Oncol.; http://hdl.handle.net/2336/611704Test; Gynecologic oncology

الإتاحة: https://doi.org/10.1016/j.ygyno.2015.04.034Test
http://hdl.handle.net/2336/611704Test

المؤلفون: Meeks, Huong D., Song, Honglin, Michailidou, Kyriaki, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Barrowdale, Daniel, Frost, Debra, McGuffog, Lesley, Ellis, Steve, Feng, Bingjian, Liang, Dong, Hulick, Peter J., Beckman, Matthias W., Olopade, Olufunmilayo I., Khan, Sofia, Thompson, Pamela J., Senter, Leigha, Olah, Edith, Doherty, Jennifer A., Mazoyer, Sylvie, Southey, Melissa C., Schildkraut, Joellen, Koppert, Linetta B., Kiemeney, Lambertus A., Massuger, Leon F. A. G., Hildebrant, Michelle A. T., Cook, Linda S., Nevanlinna, Heli, Pejovic, Tanja, Devilee, Peter, Fasching, Peter A., Neven, Patrick, Dörk, Thilo, Li, Jingmei, Borg, Ake, Öfverholm, Anna, Rossing, Mary Anne, Wentzensen, Nicolas, Henriksson, Karin, Cox, Angela, Pelttari, Liisa M., Ness, Roberta, Claes, Kathleen B. M., Cross, Simon S., Teo, Soo Hwang, Garber, Judy, Pasini, Barbara J., Shah, Mitul, Fletcher, Olivia, Kabisch, Maria, Torres, Diana, Jakubowska, Anna, Lubinski, Jan, Maerken, Tom Van, Hopper, John L., Gronwald, Jacek, Sinilnikova, Olga M., Agnarsson, Bjarni A., Modugno, Francesmary, Cramer, Daniel, Kupryjanczyk, Jolanta, Moes-Sosnowska, Joanna, Fostira, Florentia, Konstantopoulou, Irene, Tomlinson, Ian, Johnson, Nichola, Slager, Susan, Aittomäki, Kristiina, Isaacs, Claudine, Jones, Michael, Antoniou, Antonis C., Berchuck, Andrew, Swerdlow, Anthony, Terry, Kathryn L., Pearce, Leigh, Schmidt, Marjanka K., Chenevix-Trench, Georgia, Dunning, Alison M., Pharoah, Paul D. P., Hall, Per, Maugard, Christine, Butzow, Ralf, Easton, Douglas F., Sawyer, Elinor J., Couch, Fergus J., Spurdle, Amanda B., Chang-Claude, Jenny, Goldgar, David E., Poole, Elizabeth M., Riboli, Elio, Goodman, Marc T., Banerjee, Susana, Bojesen, Stig E., Tworoger, Shelley S., Bogdanova, Natalia V., Dorfling, Cecilia M., Flyger, Henrik, Flesch-Janys, Dieter, Gerdes, Anne-Marie, Figueroa, Jonine, Hansen, Thomas V. O., Buys, Saundra S., Jensen, Allen, Yoon, Sook-Yee, Czene, Kamila, Kjaer, Susanne K., Hogdall, Claus, Hogdall, Estrid, Heitz, Florian, Pedersen, Inge Sokilde, Thomassen, Mads, Benitez, Javier, González-Neira, Anna, Greene, Mark H., Osorio, Ana, Matsuo, Keitaro, Hoya, Miguel de la, Menon, Usha, Butterbach, Katja, Foretova, Lenka, Segura, Pedro Perez, Diez, Orland, Lazaro, Conxi, Brunet, Joan, Anton-Culver, Hoda, Eunjung, Lee, John, Esther M., Hosono, Satoyo, Mai, Phuong L., Neuhausen, Susan L., van Rensburg, Elizabeth J., Lindblom, Annika, Ding, Yuan Chun, Castillo, Danielle, Meindl, Alfons, Weitzel, Jeffrey N., Ganz, Patricia A., Nussbaum, Robert L., Chan, Salina B., Lu, Karen H., Karlan, Beth Y., Varon-Mateeva, Raymonda, Lester, Jenny, Loud, Jennifer T., Margolin, Sara, Wu, Anna, Gayther, Simon, Ramus, Susan J., Sieh, Weiva, Hahnen, Eric, Whittermore, Alice S., Hogervorst, Frans B. L., Peterlongo, Paolo, Monteiro, Alvaro N. A., Phelan, Catherine M., Terry, Mary Beth, Piedmonte, Marion, Rantala, Johanna, García-Closas, Montserrat, Offit, Kenneth, Robson, Mark, Levine, Douglas, Moysich, Kirsten B., Radice, Paolo, Woo, Yin Ling, Cannioto, Rikki, Wappenschmidt, Barbara, Olson, Sara H., Daly, Mary B., Nathanson, Katherine L., Kosma, Veli-Matti, Brauch, Hiltrud, Schoemaker, Minouk J., Brüning, Thomas, Viel, Alessandra, Mannermaa, Arto, Gao, Yu-Tang, Lambrechts, Diether, Tesoriero, Andrea, Barile, Monica, Burwinkel, Barbara, Peissel, Bernard, Domchek, Susan M., Manoukian, Siranoush, Godwin, Andrew K., Tung, Nadine, Montagna, Marco, Oliani, Cristina, Peixoto, Ana, Teixeira, Manuel R., Collavoli, Anita, Hallberg, Emily, Olson, Janet E., Hamann, Ute, James, Paul A., Guénel, Pascal, Goode, Ellen L., Blomqvist, Carl, Darabi, Hatef, Hart, Steven N., Shimelis, Hermela, Cunningham, Julie M., Giles, Graham G., Milne, Roger L., Healey, Sue, Tucker, Kathy, Truong, Thérèse, Marme, Frederik, Haiman, Christopher A., Singer, Christian F., Henderson, Brian E., Bruinsma, Fiona, McNeish, Iain, Goldberg, Mark S., Tischkowitz, Marc, Simard, Jacques, Soucy, Penny, Winqvist, Robert, Eccles, Diana M., Le, Nhu, Rudolph, Anja, Rappaport-Feurhauser, Christine, Borresen-Dale, Anne-Lise, Kristensen, Vessela, Salvesen, Helga B., Bjorge, Line, Siddiquil, Nadeem, Campbell, Ian G., Brenner, Hermann, Bandera, Elisa V., Risch, Harvey, Zheng, Wei, Beeghly-Fadiel, Alicia, Friedman, Eitan, Janavicius, Ramunas, Cai, Hui, Pylkäs, Katri, Tollenaar, Robert A. E. M., Ouweland, Ans M. W. van der, Stoppa-Lyonnet, Dominique, Andrulis, Irene L., Glasspool, Rosalind, Knight, Julia A., Broeks, Annegien, Narod, Steven, Laitman, Yael, Kwong, Ava, Tihomirova, Laima, Park, Sue K., Rennert, Gad, Damiola, Francesca, Imyanitov, Evgeny N.

المساهمون: 1 Univ Utah, Huntsman Canc Inst, Canc Control & Populat Sci, Salt Lake City, UT USA 2 Univ Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, Cambridge, England 3 Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England 4 Univ Utah, Sch Med, Huntsman Canc Inst, Dept Dermatol, 2000 Circle Hope Dr, Salt Lake City, UT 84112 USA 5 Univ Utah, Sch Med, Dept Med, Huntsman Canc Inst, Salt Lake City, UT USA 6 Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia 7 Univ Melbourne, Dept Pathol, Melbourne, Vic, Australia 8 Univ Melbourne, Dept Pathol, Genet Epidemiol Lab, Parkville, Vic 3052, Australia 9 KConFab Kathleen Cuningham Consortium Res Familia, Peter MacCallum Canc Ctr, Melbourne, Vic, Australia 10 Peter MacCallum Canc Ctr, Familial Canc Ctr, Melbourne, Vic, Australia 11 Univ Melbourne, Dept Oncol, Melbourne, Vic, Australia 12 Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia 13 Univ Melbourne, Peter MacCallum Canc Ctr, Sir Peter MacCallum Dept Oncol, Parkville, Vic 3052, Australia 14 QIMR Berghofer Med Res Inst, Canc Div, Brisbane, Qld, Australia 15 Peter MacCallum Canc Inst, East Melbourne, Vic, Australia 16 Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Amsterdam, Netherlands 17 Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands 18 Netherlands Canc Inst, Hereditary Breast & Ovarian Canc Res Grp Netherla, Coordinating Ctr, Amsterdam, Netherlands 19 Univ Erlangen Nurnberg, Comprehens Canc Ctr Erlangen EMN, Univ Hosp Erlangen, Dept Gynaecol & Ostetr, D-91054 Erlangen, Germany 20 Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Hematol & Oncol, Los Angeles, CA 90095 USA 21 Inst Canc Res, Div Breast Canc Res, London SW3 6JB, England 22 Inst Canc Res, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England 23 Guys Hosp, Kings Coll London, Div Canc Studies, Res Oncol, London SE1 9RT, England 24 Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England 25 Royal Marsden NHS Fdn Trust, London, England 26 Univ Coll London Elizabeth Garrett Anderson EGA, Inst Womens Hlth, Womens Canc, London, England 27 Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England 28 Univ Oxford, Oxford Biomed Res Ctr, Oxford, England 29 German Canc Res Ctr, Div Mol Genet Epidemiol, Heidelberg, Germany 30 German Canc Res Ctr, Mol Genet Breast Canc, Heidelberg, Germany 31 Heidelberg Univ, Dept Obstet & Gynecol, Heidelberg, Germany 32 Heidelberg Univ, Natl Ctr Tumor Dis, Heidelberg, Germany 33 German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany 34 State Res Inst Ctr Innovat Med, Vilnius, Lithuania 35 Latvian Biomed Res & Study Ctr, Riga, Latvia 36 Beth Israel Deaconess Med Ctr, Dept Med Oncol, Boston, MA 02215 USA 37 Dana Farber Canc Inst, Canc Risk & Prevent Clin, Boston, MA 02115 USA 38 Brigham & Womens Hosp, Obstet & Gynecol Epidemiol Ctr, 75 Francis St, Boston, MA 02115 USA 39 Brigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA 40 Harvard Univ, Sch Med, Boston, MA 02115 USA 41 Harvard Univ, Sch Publ Hlth, Dept Epidemiol, 665 Huntington Ave, Boston, MA 02115 USA 42 Univ Pretoria, Dept Genet, ZA-0002 Pretoria, South Africa 43 Univ Kansas, Med Ctr, Dept Pathol & Lab Med, Kansas City, KS 66103 USA 44 Natl Inst Hlth & Med Res, Ctr Res Epidemiol & Populat Hlth CESP, Environm Epidemiol Canc, INSERM,U1018, Villejuif, France 45 Univ Paris Sud, Villejuif, France 46 UNICANCER Genet Grp, GEMO Study Natl Canc Genet Network, Paris, France 47 Inst Curie, Dept Tumour Biol, Paris, France 48 INSERM, U830, Inst Curie, Paris, France 49 Univ Paris 05, Sorbonne Paris Cite, Paris, France 50 Univ Lyon, Ctr Rech Cancerol Lyon, INSERM,U1052, CNRS UMR 5286, Lyon, France 51 Hosp Civils Pyon, Ctr Leon Berard, Unite Mixte Genet Constitutionelle Canc Frequents, Lyon, France 52 Georgetown Univ, Lombardi Comprehens Canc Ctr, Washington, DC USA 53 Hop Univ Strasbourg, CHRU Nouvel, Lab Diagnost Genet, Hop Civil, Strasbourg, France 54 Hop Univ Strasbourg, CHRU Nouvel, Serv Oncohematol, Hop Civil, Strasbourg, France 55 Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark 56 Copenhagen Univ Hosp, Dept Clin Biochem, Herlev Hosp, Herlev, Denmark 57 Copenhagen Univ Hosp, Herlev Hosp, Dept Breast Surg, Herlev, Denmark 58 Copenhagen Univ Hosp, Rigshosp, Dept Clin Genet, Copenhagen, Denmark 59 Copenhagen Univ Hosp, Rigshosp, Ctr Genom Med, Copenhagen, Denmark 60 Danish Canc Soc, Dept Virus Lifestyle & Genes, Res Ctr, Copenhagen, Denmark 61 Univ Copenhagen, Rigshosp, Dept Gynecol, DK-2100 Copenhagen, Denmark 62 Univ Copenhagen, Herlev Hosp, Dept Pathol, Mol Unit, Copenhagen, Denmark 63 Aalborg Univ Hosp, Dept Biochem, Sect Mol Diagnost, Aalborg, Denmark 64 Odense Univ Hosp, Dept Clin Genet, DK-5000 Odense C, Denmark 65 Spanish Natl Canc Ctr CNIO, Human Canc Genet Program, Human Genet Grp, Madrid, Spain 66 Spanish Natl Canc Ctr CNIO, Human Canc Genet Program, Human Genotyping Unit CEGEN, Madrid, Spain 67 Biomed Network Rare Dis CIBERER, Madrid, Spain 68 IdISSC Inst Invest Sanitaria Hosp Clin San Carlos, Hosp Clin San Carlos, Mol Oncol Lab, Madrid, Spain 69 IdISSC, Hosp Clin San Carlos, Dept Oncol, Madrid, Spain 70 Univ Hosp Vall dHebron, VHIO, Oncogenet Grp, Barcelona, Spain 71 Univ Autonoma Barcelona, E-08193 Barcelona, Spain 72 Catalan Inst Oncol, IDIBELL Bellvitge Biomed Res Inst, Hereditary Canc Program, Mol Diagnost Unit, Barcelona, Spain 73 Catalan Inst Oncol, IDIBGI Inst Invest Biomed Girona, Hereditary Canc Program, Genet Counseling Unit, Girona, Spain 74 Univ Calif Irvine, Sch Med, Dept Epidemiol, Irvine, CA 92717 USA 75 Univ So Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA 76 Canc Prevent Inst Calif, Dept Epidemiol, Fremont, CA USA 77 Beckman Res Inst City Hope, Dept Populat Sci, Duarte, CA USA 78 City Hope Clin Canc Genet Community Res Network, Clin Canc Genet, Duarte, CA USA 79 Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Sch Med, Div Canc Prevent & Control Res, Los Angeles, CA 90024 USA 80 Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Sch Publ Hlth, Div Canc Prevent & Control Res, Los Angeles, CA 90024 USA 81 Univ Calif San Francisco, Dept Med & Genet, San Francisco, CA 94143 USA 82 Univ Calif San Francisco, Helen Diller Family Canc Ctr, Canc Risk Program, San Francisco, CA 94143 USA 83 Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Womens Canc Program, Los Angeles, CA 90048 USA 84 Stanford Univ, Dept Hlth Res & Policy Epidemiol, Stanford, CA USA 85 Univ S Florida, H Lee Moffitt Canc Ctr, Dept Canc Epidemiol, Tampa, FL 33682 USA 86 Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA 87 Roswell Pk Ctr Inst, NRG Oncol Stat & Data Management Ctr, Buffalo, NY USA 88 Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA 89 Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, 1275 York Ave, New York, NY 10021 USA 90 Roswell Pk Canc Inst, Dept Canc Prevent & Control, Buffalo, NY 14263 USA 91 Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, 1275 York Ave, New York, NY 10021 USA 92 Fox Chase Canc Ctr, Dept Clin Genet, 7701 Burholme Ave, Philadelphia, PA 19111 USA 93 Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Basser Ctr, Philadelphia, PA 19104 USA 94 Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA 95 Texas So Univ, Coll Pharm & Hlth Sci, Houston, TX 77004 USA 96 Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA 97 Univ Texas Houston, Sch Publ Hlth, Houston, TX USA 98 Univ Pittsburgh, Sch Med, Dept Obstet Gynecol & Reprod Sci, Pittsburgh, PA USA 99 Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA 100 Magee Womens Res Inst, Womens Canc Res Program, Pittsburgh, PA USA 101 Univ Pittsburgh, Inst Canc, Pittsburgh, PA USA 102 Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA 103 Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Canc Prevent & Control, Los Angeles, CA 90048 USA 104 Cedars Sinai Med Ctr, Dept Biomed Sci, Community & Populat Hlth Res Inst, Los Angeles, CA 90048 USA 105 German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany 106 German Canc Res Ctr, German Canc Consortium DKTK, Heidelberg, Germany 107 Univ Warwick, Warwick Med Sch, Div Hlth Sci, Coventry CV4 7AL, W Midlands, England 108 Tech Univ Munich, Klinikum Rechts Isar, Dept Obstet & Gynaecol, Div Tumor Genet, D-80290 Munich, Germany 109 Univ Hosp Cologne, Ctr Integrated Oncol, Cologne, Germany 110 Univ Hosp Cologne, Ctr Mol Med, Cologne, Germany 111 Univ Hosp Cologne, Ctr Familial Breast & Ovarian Canc, Cologne, Germany 112 Univ Hosp Cologne, Dept Obstet & Gynaecol, Cologne, Germany 113 Dr Margarete Fischer Bosch Inst Clin Pharmacol, Auerbachstr 112, Stuttgart, Germany 114 Univ Tubingen, Tubingen, Germany 115 Ruhr Univ Bochum IPA, German Social Accid Insurance & Inst, Inst Prevent & Occupat Med, Bochum, Germany 116 Univ Helsinki, Dept Oncol, Helsinki, Finland 117 Helsinki Univ Hosp, Helsinki, Finland 118 Univ Helsinki, Dept Obstet & Gynecol, Helsinki, Finland 119 Univ Helsinki, Dept Clin Genet, Helsinki, Finland 120 Univ Helsinki, Dept Pathol, Helsinki, Finland 121 Hannover Med Sch, Gynaecol Res Unit, Hannover, Germany 122 Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden 123 Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden 124 Karolinska Univ Hosp, Dept Clin Genet, Stockholm, Sweden 125 Univ Eastern Finland, Inst Clin Med Pathol & Forens Med, Sch Med, Kuopio, Finland 126 Kuopio Univ Hosp, Dept Clin Pathol, Imaging Ctr, SF-70210 Kuopio, Finland 127 Kuopio Univ Hosp, Ctr Canc, SF-70210 Kuopio, Finland 128 VIB, VRC, Leuven, Belgium 129 Univ Leuven, Dept Oncol, Lab Translat Genet, Leuven, Belgium 130 Univ Hosp Leuven, Dept Oncol, Multidisciplinary Breast Ctr, Leuven, Belgium 131 Univ Ghent, Ctr Med Genet, B-9000 Ghent, Belgium 132 Univ Med Ctr Hamburg Eppendorf, Inst Med Biometr & Epidemiol, Hamburg, Germany 133 Univ Med Ctr Hamburg Eppendorf, Clin Canc Registry, Dept Canc Epidemiol, Hamburg, Germany 134 Kliniken Essen Mitte Evang Huyssens Stiftung Knap, Dept Gynecol & Gynecol Oncol, Essen, Germany 135 Dr Horst Schmidt Kliniken Wiesbaden, Dept Gynecol & Gynecol Oncol, Wiesbaden, Germany 136 Charite, Campus Virchov Klinikum, Inst Human Genet, Berlin, Germany 137 Fdn Ist FIRC Oncol Mol, IFOM, Milan, Italy 138 Fdn IRCCS Ist Nazl Tumori, Dept Prevent & Predict Med, Unit Mol Bases Genet Risk & Genet Testing, Milan, Italy 139 Aviano Natl Canc Inst, CRO, Div Expt Oncol, Aviano, Italy 140 Ist Europeo Oncol, Div Canc Prevent & Genet, Milan, Italy 141 Fdn IRCCS Ist Nazl Tumori, Dept Prevent & Predict Med, Unit Med Genet, Milan, Italy 142 Veneto Inst Oncol IOV IRCCS, Immunol & Mol Oncol Unit, Padua, Italy 143 ULSS5 Ovest Vicentino, UOC Oncol, Veneto, Italy 144 Portugese Oncol Inst, Dept Genet, Oporto, Portugal 145 Univ Porto, Biomed Sci Inst ICBAS, Rua Campo Alegre 823, P-4100 Oporto, Portugal 146 Univ Pisa, Dept Lab Med, Sect Genet Oncol, Pisa, Italy 147 Univ Hosp Pisa, Pisa, Italy 148 Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA 149 Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA 150 Prince Wales Hosp, Sydney, NSW, Australia 151 McGill Univ, Royal Victoria Hosp, Div Clin Epidemiol, Montreal, PQ H3A 1A1, Canada 152 McGill Univ, Dept Med, Montreal, PQ, Canada 153 McGill Univ, Dept Human Genet, Program Canc Genet, Montreal, PQ, Canada 154 McGill Univ, Dept Oncol, Program Canc Genet, Montreal, PQ, Canada 155 Univ Cambridge, Sch Med, Cambridge, England 156 Ctr Hosp Univ Quebec, Res Ctr, Quebec City, PQ, Canada 157 Univ Laval, Quebec City, PQ, Canada 158 Univ Southampton, Fac Med, Southampton SO9 5NH, Hants, England 159 BC Canc Agcy, Canc Control Res, Vancouver, BC, Canada 160 Oslo Univ Hosp, Radiumhosp, Inst Canc Res, Dept Genet, Oslo, Norway 161 Univ Oslo, Fac Med, Inst Clin Med, Oslo, Norway 162 Univ Oslo, Oslo Univ Hosp, Dept Clin Mol Biol, Oslo, Norway 163 Haukeland Hosp, Dept Gynecol & Obstet, N-5021 Bergen, Norway 164 Univ Bergen, Dept Clin Sci, Ctr Canc Biomarkers, Bergen, Norway 165 Rutgers Canc Inst New Jersey, New Brunswick, NJ USA 166 Yale Univ, Sch Publ Hlth, Dept Chron Dis Epidemiol, New Haven, CT USA 167 Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr,Vanderbilt Ingram Canc C, Div Epidemiol,Dept Med, 221 Kirkland Hall, Nashville, TN 37235 USA 168 Univ Oulu, Dept Clin Chem, Lab Canc Genet & Tumor Biol, Oulu, Finland 169 Univ Oulu, Bioctr Oulu, Oulu, Finland 170 Northern Finland Lab Ctr Nordlab, Lab Canc Genet & Tumor Biol, Oulu, Finland 171 Erasmus Univ, Med Ctr, Dept Surg Oncol, Rotterdam, Netherlands 172 Erasmus Univ, Med Ctr, Dept Clin Genet, Family Canc Clin, Rotterdam, Netherlands 173 Mt Sinai Hosp, Lunenfeld Res Inst, Ontario Canc Genet Network, Fred A Litwin Ctr Canc Genet, Toronto, ON M5G 1X5, Canada 174 Univ Toronto, Dept Mol Genet, Toronto, ON, Canada 175 Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Prosserman Ctr Hlth Res, Toronto, ON M5G 1X5, Canada 176 Univ Toronto, Dalla Lana Sch Publ Hlth, Div Epidemiol, Toronto, ON, Canada 177 Univ Toronto, Womens Coll, Res Inst, Toronto, ON, Canada 178 Leiden Univ, Med Ctr, Dept Human Genet, Leiden, Netherlands 179 Leiden Univ, Med Ctr, Dept Pathol, Leiden, Netherlands 180 NCI, Div Canc Epidemiol & Genet, Rockville, MD USA 181 NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, NIH, Rockville, MD USA 182 Inst Canc Res, Div Genet & Epidemiol, London SW3 6JB, England 183 Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden 184 Univ Glasgow, Beatson Inst Canc Res, Wolfson Wohl Canc Res Ctr, Inst Canc Sci, Glasgow, Lanark, Scotland 185 Glasgow Royal Infirm, Dept Gynaecol Oncol, Glasgow G4 0SF, Lanark, Scotland 186 Beatson West Scotland Canc Ctr, Canc Res UK Clin Trials Unit, Glasgow, Lanark, Scotland 187 Hong Kong Sanat & Hosp, Canc Genet Ctr, Hong Kong Hereditary Breast Canc Family Registry, Hong Kong, Hong Kong, Peoples R China 188 Univ Hong Kong, Dept Surg, Hong Kong, Hong Kong, Peoples R China 189 Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea 190 Seoul Natl Univ, Coll Med, Dept Biomed Sci, Seoul, South Korea 191 Seoul Natl Univ, Coll Med, Canc Res Inst, Seoul, South Korea 192 Sime Darby Med Ctr, Canc Res Initiat Fdn, Subang Jaya, Selangor, Malaysia 193 Univ Malaya, Med Ctr, Fac Med, Canc Res Inst, Kuala Lumpur, Malaysia 194 Aichi Canc Ctr Res Inst, Div Mol Med, Nagoya, Aichi, Japan 195 Aichi Canc Ctr Res Inst, Div Epidemiol & Prevent, Nagoya, Aichi, Japan 196 Univ Malaya, Med Ctr, Dept Obstet & Gynecol, Kuala Lumpur, Malaysia 197 Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China 198 Masaryk Mem Canc Inst & Med Fac, Brno, Czech Republic 199 Med Univ Vienna, Dept Obstet & Gynecol, Vienna, Austria 200 Med Univ Vienna, Ctr Comprehens Canc, Vienna, Austria 201 Sheba Med Ctr, Susanne Levy Gertner Oncogenet Unit, Tel Hashomer, Israel 202 Carmel Hosp, Clalit Natl Israeli Canc Control Ctr, Haifa, Israel 203 Carmel Hosp, Dept Community Med & Epidemiol, Haifa, Israel 204 B Rappaport Fac Med, Haifa, Israel 205 NN Petrov Inst Oncol, St Petersburg, Russia 206 NorthShore Univ Hlth Syst, Ctr Med Genet, Evanston, IL USA 207 Univ Chicago, Med Ctr, Ctr Clin Canc Genet & Global Hlth, Chicago, IL 60637 USA 208 Ohio State Univ, Ctr Comprehens Canc, Dept Internal Med, Div Human Genet, Columbus, OH 43210 USA 209 Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary 210 Dartmouth Coll, Geisel Sch Med, Sect Biostat & Epidemiol, Dept Community & Family Med, Hanover, NH 03755 USA 211 Duke Univ, Med Ctr, Dept Community & Family Med, Durham, NC 27710 USA 212 Duke Canc Inst, Canc Control & Populat Sci, Durham, NC USA 213 Radboud Univ Nijmegen, Med Ctr, Radboud Inst Hlth Sci, NL-6525 ED Nijmegen, Netherlands 214 Radboud Univ Nijmegen, Med Ctr, Radboud Inst Mol Life Sci, Dept Gynaecol, NL-6525 ED Nijmegen, Netherlands 215 Univ New Mexico, Dept Internal Med, Div Epidemiol & Biostat, Albuquerque, NM 87131 USA 216 Oregon Hlth & Sci Univ, Dept Obstet & Gynecol, Portland, OR 97201 USA 217 Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA 218 Lund Univ, Dept Oncol, Lund, Sweden 219 Sahlgrens Univ Hosp, Dept Clin Genet, Gothenburg, Sweden 220 Fred Hutchinson Canc Res Ctr, Program Epidemiol, 1124 Columbia St, Seattle, WA 98104 USA 221 NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA 222 Univ Lund Hosp, Ctr Oncol, Reg Tumour Registry, S-22185 Lund, Sweden 223 Univ Sheffield, Sheffield Canc Res Dept Oncol, Sheffield, S Yorkshire, England 224 Univ Sheffield, Dept Neurosci, Acad Unit Pathol, Sheffield, S Yorkshire, England 225 Pontificia Univ Javeriana, Inst Human Genet, Bogota, Colombia 226 Pomeranian Med Univ, Dept Genet & Pathol, Szczecin, Poland 227 Landspitali Univ Hosp, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 228 Univ Iceland, Sch Med, Reykjavik, Iceland 229 Maria Sklodowska Curie Mem Canc Ctr, Dept Pathol & Lab Diagnost, Warsaw, Poland 230 Inst Oncol, Warsaw, Poland 231 Natl Ctr Sci Res Demokritos, Mol Diagnost Lab, Inst Nucl & Radiol Sci & Technol, Energy & Safety, Athens, Greece 232 Duke Univ, Med Ctr, Dept Obstet & Gynecol, Durham, NC 27710 USA

مصطلحات موضوعية: Brjóstakrabbamein, Arfgengi, Eggjastokkar, Krabbamein, Krabbameinsrannsóknir, Blöðruhálskirtilskrabbamein, PTT12, Adult, Aged, BRCA2 Protein/genetics, Breast Neoplasms/genetics, Codon, Terminator, Female, Genetic Predisposition to Disease, Heterozygote, Humans, Logistic Models, Lysine/genetics, Male, Middle Aged, Neoplasm Invasiveness, Odds Ratio, Ovarian Neoplasms/genetics, Ovarian Neoplasms/pathology, Polymorphism, Single Nucleotide, Prostatic Neoplasms/genetics, Risk Assessment, Risk Factors Substances

العلاقة: info:eu-repo/grantAgreement/EC/FP7/223175; http://dx.doi.orgTest/ 10.1093/jnci/djv315; http://jnci.oxfordjournals.org/content/108/2/djv315.full.pdfTest; Journal of the National Cancer Institute 2016, 108 (2):djv315; http://hdl.handle.net/2336/607166Test; Journal of the National Cancer Institute

الإتاحة: https://doi.org/10.1093/jnci/djv315Test
http://hdl.handle.net/2336/607166Test