التفاصيل البيبلوغرافية
العنوان: |
Study on Incompatibility of Traditional Chinese Medicine: Evidence from Formula Network, Chemical Space, and Metabolism Room |
المؤلفون: |
Wei Long, Xiao-Dong Zhang, Hong-Ying Wu, Jin Jin, Guang-Yun Yu, Xin He, Hao Wang, Xiu Shen, Ze-Wei Zhou, Pei-Xun Liu, Sai-Jun Fan |
بيانات النشر: |
Evidence-Based Complementary and Alternative Medicine |
سنة النشر: |
2013 |
المجموعة: |
Hindawi Publishing Corporation |
الوصف: |
A traditional Chinese medicine (TCM) formula network including 362 TCM formulas was built by using complex network methodologies. The properties of this network were analyzed including network diameter, average distance, clustering coefficient, and average degree. Meanwhile, we built a TCM chemical space and a TCM metabolism room under the theory of chemical space. The properties of chemical space and metabolism room were calculated and analyzed. The properties of the medicine pairs in “eighteen antagonisms and nineteen mutual inhibitors,” an ancient rule for TCM incompatibility, were studied based on the TCM formula network, chemical space, and metabolism room. The results showed that the properties of these incompatible medicine pairs are different from those of the other TCM based on the analysis of the TCM formula network, chemical space, and metabolism room. The lines of evidence derived from our work demonstrated that the ancient rule of TCM incompatibility, “eighteen antagonisms and nineteen mutual inhibitors,” is probably scientifically based. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
العلاقة: |
https://doi.org/10.1155/2013/352145Test |
DOI: |
10.1155/2013/352145 |
الإتاحة: |
https://doi.org/10.1155/2013/352145Test |
حقوق: |
Copyright © 2013 Wei Long et al. |
رقم الانضمام: |
edsbas.3CD535AB |
قاعدة البيانات: |
BASE |