التفاصيل البيبلوغرافية
| العنوان: |
Current Immunotherapeutic Approaches in Pancreatic Cancer |
| المؤلفون: |
Shigeo Koido, Sadamu Homma, Akitaka Takahara, Yoshihisa Namiki, Shintaro Tsukinaga, Jimi Mitobe, Shunichi Odahara, Toyokazu Yukawa, Hiroshi Matsudaira, Keisuke Nagatsuma, Kan Uchiyama, Kenichi Satoh, Masaki Ito, Hideo Komita, Hiroshi Arakawa, Toshifumi Ohkusa, Jianlin Gong, Hisao Tajiri |
| بيانات النشر: |
Clinical and Developmental Immunology |
| سنة النشر: |
2011 |
| المجموعة: |
Hindawi Publishing Corporation |
| الوصف: |
Pancreatic cancer is a highly aggressive and notoriously difficult to treat. As the vast majority of patients are diagnosed at advanced stage of the disease, only a small population is curative by surgical resection. Although gemcitabine-based chemotherapy is typically offered as standard of care, most patients do not survive longer than 6 months. Thus, new therapeutic approaches are needed. Pancreatic cancer cells that develop gemcitabine resistance would still be suitable targets for immunotherapy. Therefore, one promising treatment approach may be immunotherapy that is designed to target pancreatic-cancer-associated antigens. In this paper, we detail recent work in immunotherapy and the advances in concept of combination therapy of immunotherapy and chemotherapy. We offer our perspective on how to increase the clinical efficacy of immunotherapies for pancreatic cancer. |
| نوع الوثيقة: |
review |
| اللغة: |
English |
| العلاقة: |
https://doi.org/10.1155/2011/267539Test |
| DOI: |
10.1155/2011/267539 |
| الإتاحة: |
https://doi.org/10.1155/2011/267539Test |
| حقوق: |
Copyright © 2011 Shigeo Koido et al. |
| رقم الانضمام: |
edsbas.842C19A1 |
| قاعدة البيانات: |
BASE |
