المؤلفون: Fernández-Méndez, Rocío, Richards, Hugh K, Seeley, Helen M, Pickard, John D, Joannides, Alexis J, UKSR collaborators, Allcutt, David, Arnold, Fiona, Ashpole, Richard, Ballantyne, Eric, Bleil, Cristina, Brydon, Howard, Bulters, Diederik, Byrne, Marian, Cadoux-Hudson, Tom, Cairns, Claire, Cameron, Kerry, Cartmill, Maria, Chandler, Christopher, Choksey, Munchi S, Collins, Sally-Ann, Colthrust, Kimona, Craven, Claudia, Crimmins, Darach, Critchley, Giles, Crocker, Matthew, Cudlip, Simon, Czosnyka, Marek, Czosnyka, Zofia, D’Antona, Linda, Dewhurst, Emma, Dunn, Laurence, Edwards, Richard, Evans, Fiona, Fernandes, Helen, Fieldsend, Amy, Flint, Graham, Garnett, Matthew, Golash, Aprajay, Goodden, John, Gourley, Lois, Hallet, Jennifer, Hardy, Jan, Hennigan, Dawn, Herbert, Katie, Hinde, Liz, Holliman, Damian, Hutchinson, Peter, Jenkinson, Michael, Kamaly, Ian, Kandasamy, Jothy, Keong, Nicole, Kewin, Sara, King, Andrew, Kolias, Angelos, Kvedaras, Sarah, Lalou, Afroditi, Leach, Paul, MacArthur, Donald, Mallucci, Conor, Martin, John, Mathew, Bruce, McConnell, Roy, McMahon, Catherine, McMullan, John, Moran, Emma, Mukerji, Nitin, Nabbanja, Eva, O'Kane, Roddy, O’Connor, Jody, O’Reilly, Gerry, Papadopoulos, Marios, Pople, Ian, Rajaraman, Chittoor, Ramirez, Roberto, Ramos, Joana, Ross, Sheila, Ross, Nicholas, Santarius, Thomas, Saxena, Amar, Shanmuganathan, Mano, Sinha, Saurabh, Solanki, Guirish, Strachan, Roger, Thompson, Dominic, Thompson, Simon, Thorne, John, Thorne, Lewis, Thurlby, Kim, Tisdall, Martin, Tizzard, Simon, Todd, Lorraine, Toma, Ahmed, Turner, Carole, Ushewokunze, Shungu, Vindlacheruvu, Raghu, Wadley, John, Watkins, Laurence, Whitfield, Peter, Wilson, Mark, Zebian, Bassel

مصطلحات موضوعية: Neurosurgery

الوصف: Objectives To determine current epidemiology and clinical characteristics of cerebrospinal fluid (CSF) shunt surgery, including revisions. Methods A retrospective, multicentre, registry-based study was conducted based on 10 years’ data from the UK Shunt Registry, including primary and revision shunting procedures reported between 2004 and 2013. Incidence rates of primary shunts, descriptive statistics and shunt revision rates were calculated stratified by age group, geographical region and year of operation. Results 41 036 procedures in 26 545 patients were submitted during the study period, including 3002 infants, 4389 children and 18 668 adults. Procedures included 20 947 (51.0%) primary shunt insertions in 20 947 patients, and 20 089 (49.0%) revision procedures. Incidence rates of primary shunt insertions for infants, children and adults were 39.5, 2.4 and 3.5 shunts per 100 000 person-years, respectively. These varied by geographical subregion and year of operation. The most common underlying diagnoses were perinatal intraventricular haemorrhage (35.3%) and malformations (33.9%) in infants, tumours (40.5%) and malformations (16.3%) in children, and tumours (24.6%), post-haemorrhagic hydrocephalus (16.2%) and idiopathic normal pressure hydrocephalus (14.2%) in adults. Ninety-day revision rates were 21.9%, 18.6% and 12.8% among infants, children and adults, respectively, while first-year revision rates were 31.0%, 25.2% and 17.4%. The main reasons for revision were underdrainage and infection, but overdrainage and mechanical failure continue to pose problems. Conclusions Our report informs patients, carers, clinicians, providers and commissioners of healthcare, researchers and industry of the current epidemiology of shunting for CSF disorders, including the potential risks of complications and frequency of revision.

وصف الملف: text/html

العلاقة: http://jnnp.bmj.com/cgi/content/short/90/7/747Test; http://dx.doi.org/10.1136/jnnp-2018-319927Test

الإتاحة: https://doi.org/10.1136/jnnp-2018-319927Test
http://jnnp.bmj.com/cgi/content/short/90/7/747Test

المؤلفون: Craven, Claudia Louise, Chapman, Miles D, D’Antona, Linda, Thompson, Simon D, Lakdawala, Neghat, Zetterberg, Henrik, Watkins, Laurence D, Toma, Ahmed K

مصطلحات موضوعية: PostScript

وصف الملف: text/html

العلاقة: http://jcp.bmj.com/cgi/content/short/72/1/91Test; http://dx.doi.org/10.1136/jclinpath-2018-205296Test

الإتاحة: https://doi.org/10.1136/jclinpath-2018-205296Test
http://jcp.bmj.com/cgi/content/short/72/1/91Test