دورية أكاديمية
Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values
| العنوان: | Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values |
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| المؤلفون: | Pedersen, Brent S., Schwartz, David A., Yang, Ivana V., Kechris, Katerina J. |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2012 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | SEQUENCE ANALYSIS |
| الوصف: | Summary: comb-p is a command-line tool and a python library that manipulates BED files of possibly irregularly spaced P -values and (1) calculates auto-correlation, (2) combines adjacent P -values, (3) performs false discovery adjustment, (4) finds regions of enrichment (i.e. series of adjacent low P -values) and (5) assigns significance to those regions. In addition, tools are provided for visualization and assessment. We provide validation and example uses on bisulfite-seq with P -values from Fisher’s exact test, tiled methylation probes using a linear model and Dam-ID for chromatin binding using moderated t -statistics. Because the library accepts input in a simple, standardized format and is unaffected by the origin of the P -values, it can be used for a wide variety of applications. Availability: comb-p is maintained under the BSD license. The documentation and implementation are available at https://github.com/brentp/combined-pvaluesTest . Contact: bpederse@gmail.com |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://bioinformatics.oxfordjournals.org/cgi/content/short/28/22/2986Test; http://dx.doi.org/10.1093/bioinformatics/bts545Test |
| DOI: | 10.1093/bioinformatics/bts545 |
| الإتاحة: | https://doi.org/10.1093/bioinformatics/bts545Test http://bioinformatics.oxfordjournals.org/cgi/content/short/28/22/2986Test |
| حقوق: | Copyright (C) 2012, Oxford University Press |
| رقم الانضمام: | edsbas.CEC963F4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/bioinformatics/bts545 |
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