التفاصيل البيبلوغرافية
| العنوان: |
Performance of Covid-19 antigen rapid diagnostic tests for self-testing compared with antigen testing by professionals and molecular tests: A systematic review and meta-analysis [Research Data] |
| المؤلفون: |
Katzenschlager, Stephan, Brümmer, Lukas E., Schmitz, Stephani, Tolle, Hannah, Manten, Katharina, Gaeddert, Mary, Erdmann, Christian, Lindner, Andreas, Tobian, Frank, Grilli, Maurizio, Pollock, Nira R., Mace, Aurélien, Erkosar, Berra, Carmona, Sergio, Ongarello, Stefano, Johnson, Cheryl C., Sacks, Jilian A., Denkinger, Claudia M., Yerlikaya, Seda |
| بيانات النشر: |
heiDATA |
| سنة النشر: |
2022 |
| المجموعة: |
heiDATA Dataverse Network (Universität Heidelberg) |
| مصطلحات موضوعية: |
Medicine, Health and Life Sciences, SARS-CoV-2, Ag-RDT, antigen testing, systematic review, self testing |
| الوصف: |
Objectives Self-testing is an effective tool to bridge the testing gap for a number of infectious diseas-es; however, its performance using SARS-CoV-2 antigen-detection rapid diagnostic tests (Ag-RDTs) has not been systematically reviewed. We evaluated the accuracy of COVID-19 self-testing and/or self-sampling using Ag-RDTs to inform WHO guideline development. Methods: We searched multiple databases for articles evaluating the accuracy of COVID-19 self-testing or self-sampling through November 19th, 2021. Cohen’s kappa was estimated to as-sess concordance between self-testing/self-sampling and solely professional-use Ag-RDT results. Meta-analysis was performed to obtain pooled performance estimates compared to molecular testing. The QUADAS-2 and GRADE tools were used to evaluate quality and cer-tainty of evidence. Results: Of 12,946 publications, 19 were eligible; two reported on self-testing, while 17 studies as-sessed self-sampling only. Risk of bias was low (28.1%). Overall concordance with profes-sional-use Ag-RDTs (n=5) was high (kappa 0.92 [95% confidence interval (CI) 0.89 to 0.95]). Overall pooled sensitivity of Ag-RDT testing using self-testing/self-sampling was 72.0% (95% CI 62.4 to 80.0). Conclusion: COVID-19 self-testing/self-sampling exhibits reasonable performance and high concordance with professional-use Ag-RDTs. This suggest that self-sampling, at a minimum, can be offered as part of COVID-19 testing strategies, despite high heterogeneity among studies and the paucity of data. |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| العلاقة: |
https://doi.org/10.11588/data/P9JEPGTest |
| DOI: |
10.11588/data/P9JEPG |
| الإتاحة: |
https://doi.org/10.11588/data/P9JEPGTest |
| رقم الانضمام: |
edsbas.E7F55EE4 |
| قاعدة البيانات: |
BASE |
