دورية أكاديمية
Radical Coupling Allows a Fast and Tuned Synthesis of Densely Packed Polyrotaxanes Involving γ-Cyclodextrins and Polydimethylsiloxane
| العنوان: | Radical Coupling Allows a Fast and Tuned Synthesis of Densely Packed Polyrotaxanes Involving γ-Cyclodextrins and Polydimethylsiloxane |
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| المؤلفون: | Blin, François, Przybylski, Cédric, Bonnet, Véronique, Clément, Marie-Jeanne, Curmi, Patrick. A., Choppinet, Patricia, Nakajima, Tatsutoshi, Cheradame, Hervé, Jarroux, Nathalie |
| المساهمون: | Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378 (LG2A ), Université de Picardie Jules Verne (UPJV)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Structure et activité des biomolécules normales et pathologiques (SABNP), Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Menicon Co. |
| المصدر: | ISSN: 0024-9297. |
| بيانات النشر: | HAL CCSD American Chemical Society |
| سنة النشر: | 2016 |
| المجموعة: | HAL-CEA (Commissariat à l'énergie atomique et aux énergies alternatives) |
| مصطلحات موضوعية: | Chromatography, Cyclodextrins, Hydrogels, Mass spectrometry, Microchannels, Polydimethylsiloxane, Analytical characterization, Gamma-cyclodextrin, High conversions, Synthesis process, Silicones, Size exclusion chromatography, Supramolecular assemblies, Molecular necklace, Polydimethylsiloxane PDMS, MALDI-TOF mass spectrometry, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; The first radical end-coupling synthesis of polydimethylsiloxane (PDMS)-γ-cyclodextrins (γ-CDs) based polyrotaxane is reported. Conversely to usual chemical way, the radical process leads to fast both controlled size and structure with minimal side reaction while exhibiting very high conversion rate (w/w, 80%). Pure PDMS-γ-CDs molecular necklaces were successfully isolated by preparative size exclusion chromatography and finely characterized both by 1D/2D/STD 1H and 13C NMR and MALDI-TOF mass spectrometry. The observations give clear evidence of the supramolecular assembly synthesis where the filling ratio (γ-CD/monomer unit) of PDMS chains is as high as 40% of γ-CDs. Combination of such radical-based coupling supported by detailed analytical characterizations appears at the forefront of a fast, suitable, and easily amenable scaling-up CDs-based polyrotaxane synthesis process. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-02065253; https://hal.science/hal-02065253Test |
| DOI: | 10.1021/acs.macromol.6b00492 |
| الإتاحة: | https://doi.org/10.1021/acs.macromol.6b00492Test https://hal.science/hal-02065253Test |
| رقم الانضمام: | edsbas.D1CC94CE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acs.macromol.6b00492 |
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